96. Crohn disease Clinical trials / Disease details

Clinical trials : 2,400 / Drugs : 1,391 - (DrugBank : 267) / Drug target genes : 170 - Drug target pathways : 215

15 trials found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04991324 (ClinicalTrials.gov)	September 2022	27/7/2021	Cholecalciferol Comedication in IBD - the 5C Study	Cholecalciferol Comedication in Chronic Inflammatory Bowel Diseases (Crohn's Disease or Ulcerative Colitis) - the 5C Study	Inflammatory Bowel Diseases	Drug: Vitamin D3	University Hospital, Basel, Switzerland	NULL	Not yet recruiting	18 Years	N/A	All	150	Phase 3	NULL
2	NCT04331639 (ClinicalTrials.gov)	November 1, 2020	23/3/2020	High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Biologic Therapy	Implementation of High Dose Interval Vitamin D Supplementation in Patients With Inflammatory Bowel Disease Receiving Infliximab or Vedolizumab	Inflammatory Bowel Disease;Crohn Disease;Ulcerative Colitis;Vitamin D Deficiency	Dietary Supplement: vitamin D3	Boston Children's Hospital	NULL	Recruiting	5 Years	25 Years	All	50	Phase 2	United States
3	NCT04225819 (ClinicalTrials.gov)	October 1, 2020	3/1/2020	Adjunctive Treatment With Vitamin D3 in Patients With Active IBD	Adjunctive Treatment With Vitamin D3 in Patients With Active IBD (ACTIVATED): A Randomized, Double-blind, Placebo-controlled Trial	IBD;Inflammatory Bowel Diseases;Crohn Disease;Ulcerative Colitis;Vitamin D3 Deficiency	Dietary Supplement: Vitamin D3;Other: Placebo	Massachusetts General Hospital	NULL	Recruiting	18 Years	N/A	All	100	N/A	United States
4	NCT03999580 (ClinicalTrials.gov)	February 7, 2020	24/6/2019	The Vitamin D in Pediatric Crohn's Disease ( ViDiPeC-2 )	A Pragmatic Randomized Controlled Trial on High Dose Vitamin D to Prevent Relapses of Crohn's Disease in Children	Crohn Disease	Drug: vitamin D3	Jantchou Prevost	NULL	Recruiting	4 Years	18 Years	All	316	Phase 3	Canada
5	NCT03162432 (ClinicalTrials.gov)	August 1, 2017	15/5/2017	High Dose Interval Vitamin D Supplementation in Patients With IBD Receiving Remicade	High Dose Interval Vitamin D Supplementation in Patients With IBD Receiving Remicade	IBD;Ulcerative Colitis;Crohn Disease	Drug: Vitamin D3	Boston Children's Hospital	NULL	Completed	7 Years	25 Years	All	50	Phase 3	United States
6	NCT02186275 (ClinicalTrials.gov)	February 2016	4/7/2014	The Vitamin D in Pediatric Crohn's Disease	Randomized Controlled Trial of High Dose Vitamin D in Children With Newly Diagnosed Crohn's Disease for the Prevention of Relapses	Crohn's Disease	Drug: Vitamin D3 : 3000 or 4000 UI/day then 2,000 UI/day;Drug: Vitamin D3 800 UI/day then 800 UI/day	St. Justine's Hospital	Canadian Institutes of Health Research (CIHR)	Completed	9 Years	18 Years	All	25	Phase 3	Canada
7	EUCTR2013-002838-20-BE (EUCTR)	09/12/2014	15/09/2014	The effect of Vitamin D to prevent post-operative relapse of Crohn's Disease	The effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT	Crohn's Disease MedDRA version: 19.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: D-CURA Product Name: D-Cura INN or Proposed INN: Cholecalciferol Other descriptive name: CHOLECALCIFEROL CONCENTRATE (WATER-DISPERSIBLE FORM)	Academic Medical Center	NULL	Not Recruiting			Female: yes Male: yes	142	Phase 3	Belgium;Netherlands
8	NCT04606017 (ClinicalTrials.gov)	January 1, 2014	25/10/2020	Effect of Vitamin D Supplementation on Infliximab Response in Patients With Crohn's Disease	Influence of Vitamin D3 Supplementation on Infliximab Efficacy in Chinese Patients With Crohn's Disease: A Retrospective Cohort Study	Crohn Disease;Vitamin D Deficiency;Vitamin D Supplement	Drug: Caltrate Pill	Second Affiliated Hospital of Wenzhou Medical University	NULL	Completed	18 Years	N/A	All	70		China
9	NCT02615288 (ClinicalTrials.gov)	January 2014	23/11/2015	High Dose Vitamin D3 in Crohn's Disease	Impact of High Dose Vitamin D3 Supplementation in Treatment of Crohn's Disease in Remission: A Randomized Double-blind Controlled Study	Crohn's Disease	Dietary Supplement: Vitamin D3	McMaster University	Canadian Association of Gastroenterology	Completed	18 Years	70 Years	Both	40	N/A	NULL
10	EUCTR2013-002838-20-NL (EUCTR)	12/11/2013	06/09/2013	The effect of Vitamin D to prevent post-operative relapse of Crohn's Disease	The effect of Vitamin D3 to prevent post-operative relapse of Crohn’s Disease: a placebo-controlled randomized trial (DETECT) - DETECT	Crohn's Disease MedDRA version: 18.0;Level: PT;Classification code 10011401;Term: Crohn's disease;System Organ Class: 10017947 - Gastrointestinal disorders;Therapeutic area: Diseases [C] - Digestive System Diseases [C06]	Trade Name: InVita D3 INN or Proposed INN: Colecalciferol Other descriptive name: CHOLECALCIFEROL CONCENTRATE	Academic Medical Center	NULL	Not Recruiting			Female: yes Male: yes	142	Phase 3	Belgium;Netherlands
11	NCT01864616 (ClinicalTrials.gov)	July 2013	22/5/2013	The Impact of Vitamin D on Disease Activity in Crohn's Disease		Crohn Disease	Dietary Supplement: Vitamin D3	University of Saskatchewan	Dania Alrefai;Dr.Jennifer Jones;Dr.Hani Jawa;Dr.Wael El-matary;Saudi Arabian Cultural Bureau	Terminated	16 Years	70 Years	All	9	N/A	Canada;Saudi Arabia
12	NCT02010762 (ClinicalTrials.gov)	February 2013	10/12/2013	The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease	The Effect of Vitamin D3 to Maintain Surgical Remission in Postoperative Crohn's Disease: a Placebo-controlled Randomized Trial	Crohn's Disease	Drug: Vitamin D;Drug: Placebo	Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)	NULL	Completed	18 Years	N/A	All	142	Phase 4	Netherlands
13	NCT01692808 (ClinicalTrials.gov)	October 2012	17/9/2012	Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease	Bioavailability of Vitamin D in Children and Adolescents With Crohn's Disease.	Crohn's Disease	Drug: Vitamin D3 3000 UI daily;Drug: Vitamin D3 4000 UI daily	St. Justine's Hospital	NULL	Completed	10 Years	18 Years	Both	20	Phase 2	Canada
14	NCT01369667 (ClinicalTrials.gov)	April 2012	7/6/2011	Vitamin D Supplementation in Adult Crohn's Disease	Vitamin D and Immunomodulation: Effects in Crohn's Disease	Crohn's Disease	Dietary Supplement: Vitamin D3;Other: Placebo	University of Dublin, Trinity College	Queen Mary University of London	Completed	18 Years	75 Years	Both	117	Phase 4	Ireland
15	NCT01877577 (ClinicalTrials.gov)	April 2012	11/6/2013	Supplementation of Vitamin D3 in Patients With Inflammatory Bowel Diseases and Hypovitaminosis D	Supplementation of Vitamin D3 (Cholecalciferol) in Patients With Inflammatory Bowel Diseases (IBD) and Hypovitaminosis D: A Prospective Randomized Controlled Trial.	Crohn's Disease (CD);Ulcerative Colitis (UC)	Dietary Supplement: Vitamin D3	University of California, San Francisco	NULL	Completed	18 Years	N/A	Both	30	N/A	United States