Trofinetide ( DrugBank: Trofinetide )
1 disease
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 156 | Rett syndrome | 4 |
156. Rett syndrome
Clinical trials : 40 / Drugs : 53 - (DrugBank : 19) / Drug target genes : 77 - Drug target pathways : 113
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04988867 (ClinicalTrials.gov) | September 22, 2021 | 23/7/2021 | An Open-Label Study of Trofinetide for the Treatment of Girls Two to Five Years of Age Who Have Rett Syndrome | An Open-Label Study of Trofinetide for the Treatment of Girls Two to Five Years of Age Who Have Rett Syndrome | Rett Syndrome | Drug: Trofinetide | ACADIA Pharmaceuticals Inc. | NULL | Recruiting | 2 Years | 5 Years | Female | 10 | Phase 2/Phase 3 | United States |
| 2 | NCT04776746 (ClinicalTrials.gov) | November 8, 2020 | 29/11/2020 | Open-Label Extension Study of Trofinetide for Rett Syndrome | An Open-Label Extension Study of Continuing Treatment With Trofinetide for Rett Syndrome | Rett Syndrome | Drug: trofinetide | ACADIA Pharmaceuticals Inc. | NULL | Enrolling by invitation | 5 Years | 22 Years | Female | 153 | Phase 3 | United States |
| 3 | NCT04279314 (ClinicalTrials.gov) | January 29, 2020 | 19/2/2020 | Open-Label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome | A 40-Week, Open-label Extension Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome | Rett Syndrome | Drug: Trofinetide | ACADIA Pharmaceuticals Inc. | NULL | Active, not recruiting | 5 Years | 21 Years | Female | 180 | Phase 3 | United States |
| 4 | NCT04181723 (ClinicalTrials.gov) | November 6, 2019 | 26/11/2019 | Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome (LAVENDER™) | A Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study of Trofinetide for the Treatment of Girls and Women With Rett Syndrome | Rett Syndrome | Drug: Trofinetide;Other: Placebo | ACADIA Pharmaceuticals Inc. | NULL | Completed | 5 Years | 20 Years | Female | 187 | Phase 3 | United States |