CLS ( DrugBank: - )
3 diseases
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 2 | Amyotrophic lateral sclerosis | 1 |
| 46 | Malignant rheumatoid arthritis | 1 |
| 71 | Idiopathic osteonecrosis of the femoral head | 1 |
2. Amyotrophic lateral sclerosis
Clinical trials : 624 / Drugs : 611 - (DrugBank : 160) / Drug target genes : 172 - Drug target pathways : 225
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT04948645 (ClinicalTrials.gov) | September 22, 2021 | 23/6/2021 | A Phase 1 Study to Investigate the Safety and Pharmacokinetics of ABBV-CLS-7262 in Patients With Amyotrophic Lateral Sclerosis | A Randomized, Double-Blind, Placebo-Controlled Study to Assess Safety, Tolerability, and Pharmacokinetics Following Multiple Doses of ABBV-CLS-7262 in Subjects With Amyotrophic Lateral Sclerosis Followed by an Active Treatment Extension | ALS;Amyotrophic Lateral Sclerosis | Drug: ABBV-CLS-7262;Drug: Placebo | Calico Life Sciences LLC | AbbVie | Recruiting | 18 Years | 80 Years | All | 30 | Phase 1 | United States;Canada |
46. Malignant rheumatoid arthritis
Clinical trials : 4,325 / Drugs : 2,671 - (DrugBank : 417) / Drug target genes : 187 - Drug target pathways : 224
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03410940 (ClinicalTrials.gov) | January 7, 2011 | 19/1/2018 | PMCF Study of the CLS Brevius Stem With Kinectiv Technology | Post-Market Clinical Follow-Up (PMCF) Study of the CLS Brevius Stem With Kinectiv Technology | Osteoarthritis;Avascular Necrosis;Rheumatoid Arthritis;Femoral Neck Fractures;Prosthesis Failure | Device: CLS Brevius stem with Kinectiv technology | Zimmer Biomet | NULL | Terminated | 18 Years | N/A | All | 223 | Italy;Poland;Spain |
71. Idiopathic osteonecrosis of the femoral head
Clinical trials : 3 / Drugs : 5 - (DrugBank : 4) / Drug target genes : 4 - Drug target pathways : 11
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT03112785 (ClinicalTrials.gov) | March 17, 2011 | 7/3/2017 | Fitmore Versus CLS Stem in Total Hip Arthroplasty. Bilateral One-stage Operations | Randomized Comparison Between the Fitmore and the CLS Stem in Patients Operated in One-stage Due to Bilateral Symptomatous Hip Disease | Primary Hip Osteoarthritis;Secondary Hip Osteoarthritis Due to Idiopathic Femoral Head Necrosis, Childhood or Inflammatory Disease;Bilateral Hip Disease;Surgical Treatment | Device: Total hip arthroplasty (Fitmore or CLS uncemented femoral stem made by Zimmer-Biomet, Warshaw, USA) | Sahlgrenska University Hospital, Sweden | Zimmer Biomet | Active, not recruiting | 35 Years | 75 Years | All | 44 | N/A | NULL |