MRNA-3705 ( DrugBank: - )


1 disease
IDDisease name (Link within this page)Number of trials
246Methylmalonic acidemia1

246. Methylmalonic acidemia


Clinical trials : 19 Drugs : 26 - (DrugBank : 3) / Drug target genes : 17 - Drug target pathways : 23
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04899310
(ClinicalTrials.gov)
August 6, 202119/5/2021A Study to Assess Safety, Pharmacokinetics, and Pharmacodynamics of mRNA-3705 in Participants With Isolated Methylmalonic AcidemiaA Global, Phase 1/2, Open-Label, Dose Optimization Study to Evaluate the Safety, Tolerability, Pharmacodynamics, and Pharmacokinetics of mRNA-3705 in Participants With Isolated Methylmalonic Acidemia Due to Methylmalonyl-CoA Mutase DeficiencyMethylmalonic AcidemiaBiological: mRNA-3705ModernaTX, Inc.NULLRecruiting1 YearN/AAll33Phase 1/Phase 2Canada;United Kingdom