Diagnostic Test: Brain MRI ( DrugBank: - )


2 diseases
IDDisease name (Link within this page)Number of trials
25Progressive multifocal leukoencephalopathy1
229Autoimmune pulmonary alveolar proteinosis1

25. Progressive multifocal leukoencephalopathy


Clinical trials : 25 Drugs : 35 - (DrugBank : 21) / Drug target genes : 8 - Drug target pathways : 37
No.TrialIDDate_
enrollment
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registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
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agemin
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agemax
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PhaseCountries
1NCT04453917
(ClinicalTrials.gov)
February 23, 20213/6/2020Dynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal LeukoencephalopathyDynamics of T Cell Expression of Immune Checkpoint Molecules in Progressive Multifocal LeukoencephalopathyProgressive Multifocal LeukoencephalopathyBiological: Collection of blood and urine;Biological: Spinal tap;Diagnostic Test: Brain MRI;Biological: Neurological evaluationUniversity Hospital, ToulouseNULLRecruiting18 YearsN/AAll15N/AFrance

229. Autoimmune pulmonary alveolar proteinosis


Clinical trials : 43 Drugs : 34 - (DrugBank : 8) / Drug target genes : 3 - Drug target pathways : 14
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT03887169
(ClinicalTrials.gov)
September 16, 201912/3/2019Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene.Oral or Enteral Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene.Pulmonary Alveolar Proteinosis;Mutation Ala393Thr of the MARS Gene;mutationSer567Leu of the MARS GeneDrug: Methionine;Drug: Vitamin B12, B9, B6, C supplementation;Diagnostic Test: Methionine/homocysteine Dosage;Diagnostic Test: Thoracic CT scan;Diagnostic Test: Abdominal and liver ultrasound.;Diagnostic Test: Brain MRIAssistance Publique - Hôpitaux de ParisNULLCompletedN/A18 YearsAll3Phase 1/Phase 2France