5-probe cocktail ( DrugBank: - )


1 disease
IDDisease name (Link within this page)Number of trials
254Porphyria1

254. Porphyria


Clinical trials : 70 Drugs : 54 - (DrugBank : 19) / Drug target genes : 19 - Drug target pathways : 35
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PhaseCountries
1NCT03505853
(ClinicalTrials.gov)
April 26, 201813/4/2018A Study to Investigate the Interaction Between Givosiran and a 5-probe Drug Cocktail in Patients With Acute Intermittent Porphyria (AIP)A Drug-Drug Interaction Study to Investigate the Effect of Givosiran on the Pharmacokinetics (PK) of Midazolam, Caffeine, Losartan, Omeprazole, and Dextromethorphan in Patients With Acute Intermittent Porphyria (AIP) Who Are Asymptomatic High Excreters (ASHE)Acute Intermittent Porphyria (AIP);Acute Hepatic Porphyria (AHP);Porphyria, Acute Intermittent;Acute PorphyriaDrug: Givosiran;Drug: 5-probe cocktailAlnylam PharmaceuticalsNULLCompleted18 Years65 YearsAll10Phase 1Sweden