LUM001 (Maralixibat) ( DrugBank: Maralixibat )


1 disease
IDDisease name (Link within this page)Number of trials
297Alagille syndrome2

297. Alagille syndrome


Clinical trials : 43 Drugs : 19 - (DrugBank : 9) / Drug target genes : 2 - Drug target pathways : 2
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PhaseCountries
1NCT02117713
(ClinicalTrials.gov)
March 16, 201516/4/2014An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille SyndromeA Multicenter Extension Study to Evaluate the Long-Term Safety and Durability of the Therapeutic Effect of LUM001, an Apical Sodium-Dependent Bile Acid Transporter Inhibitor (ASBTi), in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille SyndromeAlagille SyndromeDrug: LUM001 (Maralixibat)Mirum Pharmaceuticals, Inc.Lumena Pharmaceuticals, Inc.;Childhood Liver Disease Research and Education NetworkCompleted1 Year18 YearsAll34Phase 2United States;Canada
2NCT02047318
(ClinicalTrials.gov)
December 20, 201323/1/2014An Extension Study to Evaluate the Long-Term Safety and Durability of Effect of LUM001 in the Treatment of Cholestatic Liver Disease in Subjects With Alagille Syndrome (ALGS)A Multicentre Extension Study to Evaluate the Long-Term Safety and Durability of the Therapeutic Effect of LUM001 Also Known as Maralixibat (MRX), an Apical Sodium-Dependent Bile Acid Transporter Inhibitor (ASBTi), in the Treatment of Cholestatic Liver Disease in Pediatric Subjects With Alagille SyndromeAlagille SyndromeDrug: LUM001 (Maralixibat)Mirum Pharmaceuticals, Inc.NULLCompleted12 Months18 YearsAll19Phase 2United Kingdom