Zoledronic acid, pravastatin ( DrugBank: Pravastatin, Zoledronic acid )
1 disease
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 333 | Hutchinson-Gilford syndrome | 3 |
333. Hutchinson-Gilford syndrome
Clinical trials : 7 / Drugs : 8 - (DrugBank : 3) / Drug target genes : 4 - Drug target pathways : 6
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT00916747 (ClinicalTrials.gov) | August 2009 | 5/6/2009 | Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria | An Open Label Phase II Trial of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Hutchinson-Gilford Progeria Syndrome(HGPS) and Progeroid Laminopathies | Progeria | Drug: Lonafarnib, Zoledronic Acid, and Pravastatin | Boston Children's Hospital | Schering-Plough;Merck Sharp & Dohme Corp.;Eiger BioPharmaceuticals | Active, not recruiting | N/A | N/A | All | 85 | Phase 2 | United States |
| 2 | NCT00879034 (ClinicalTrials.gov) | March 2009 | 8/4/2009 | A Study of Zoledronic Acid, Pravastatin, and Lonafarnib for Patients With Progeria | A Phase II Pilot Study of Zoledronic Acid, Pravastatin, and Lonafarnib (SCH66336) for Patients With Hutchinson-Gilford Progeria Syndrome (HGPS) and Progeroid Laminopathies | Progeria;Hutchinson-Gilford Syndrome | Drug: Lonafarnib;Drug: Zoledronic Acid;Drug: Pravastatin | Boston Children's Hospital | Dana-Farber Cancer Institute;Brigham and Women's Hospital;Schering-Plough | Completed | N/A | N/A | All | 5 | Phase 2 | United States |
| 3 | NCT00731016 (ClinicalTrials.gov) | October 2008 | 1/8/2008 | Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledronic Acid | Treatment of the Hutchinson-Gilford Progeria Syndrome With a Combination of Pravastatin and Zoledronic Acid | Hutchinson-Gilford Progeria Syndrome | Drug: Zoledronic acid, pravastatin | Assistance Publique Hopitaux De Marseille | NULL | Completed | 3 Years | N/A | Both | 15 | Phase 2 | France |