L-Arginine ( DrugBank: Arginine, L-arginine )

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3 diseases

ID	Disease name (Link within this page)	Number of trials
46	Malignant rheumatoid arthritis	1
113	Muscular dystrophy	2
299	Cystic fibrosis	1

46. Malignant rheumatoid arthritis

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Clinical trials : 4,325 /  Drugs : 2,671 - (DrugBank : 417) / Drug target genes : 187 - Drug target pathways : 224

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04535427 (ClinicalTrials.gov)	January 1, 2021	22/8/2020	Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis	Role of L-Arginine Supplementation in the Treatment of Rheumatoid Arthritis	Rheumatoid Arthritis	Drug: L-arginine;Drug: Placebo	RenJi Hospital	NULL	Not yet recruiting	18 Years	45 Years	All	144	Phase 2	China

113. Muscular dystrophy

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Clinical trials : 622 /  Drugs : 485 - (DrugBank : 99) / Drug target genes : 59 - Drug target pathways : 168

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02516085 (ClinicalTrials.gov)	January 2012	3/8/2015	Improved Muscle Function in Duchenne Muscular Dystrophy Through L-Arginine and Metformin		Duchenne Muscular Dystrophy	Drug: Metformin;Drug: L-Arginine	University Hospital, Basel, Switzerland	NULL	Completed	7 Years	10 Years	Both	5	Phase 1	NULL
2	NCT01388764 (ClinicalTrials.gov)	January 2012	5/7/2011	Safety, Tolerability and Effects of L-Arginine in Boys With Dystrophinopathy on Corticosteroids	Pilot Study: To Assess the Safety, Tolerability and Effects of L-Arginine on Muscles in Boys With Dystrophinopathy on Corticosteroids	Dystrophinopathy;Duchenne Muscular Dystrophy;Becker's Muscular Dystrophy	Drug: L-arginine	Massachusetts General Hospital	NULL	Completed	7 Years	11 Years	Male	7	Phase 1	United States

299. Cystic fibrosis

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Clinical trials : 1,696 /  Drugs : 1,644 - (DrugBank : 272) / Drug target genes : 96 - Drug target pathways : 170

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00405665 (ClinicalTrials.gov)	November 2006	28/11/2006	The Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis	Pilot Study of the Short Term Safety and Efficacy of Inhaled L-arginine in Patients With Cystic Fibrosis	Cystic Fibrosis	Drug: L-arginine	The Hospital for Sick Children	NULL	Completed	14 Years	N/A	Both	20	Phase 2	Canada