Simponi® ( DrugBank: - )

3 diseases

ID	Disease name (Link within this page)	Number of trials
46	Malignant rheumatoid arthritis	1
97	Ulcerative colitis	3
271	Ankylosing spondylitis	2

46. Malignant rheumatoid arthritis

Clinical trials : 4,325 / Drugs : 2,671 - (DrugBank : 417) / Drug target genes : 187 - Drug target pathways : 224

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01313858 (ClinicalTrials.gov)	April 2010	10/3/2011	A Study to Investigate the Use of Golimumab (Simponi®) in Participants With Rheumatoid Arthritis, Ps ...	Non-Interventional Study Investigating the Use of Golimumab (Simponi®) in Patients With Rheumatoid A ...	Arthritis, Rheumatoid;Arthritis, Psoriatic;Spondylitis, Ankylosing	Drug: Simponi®;Drug: Methotrexate	Merck Sharp & Dohme Corp.	NULL	Completed	18 Years	N/A	All	1613	N/A	Germany

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97. Ulcerative colitis

Clinical trials : 2,527 / Drugs : 1,465 - (DrugBank : 259) / Drug target genes : 144 - Drug target pathways : 202

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2018-001510-15-DE (EUCTR)	02/05/2019	19/11/2018	A Proof-of-concept Study of the Efficacy and Safety of Combination Therapy With Guselkumab and Golim ...	A Phase 2a Randomized, Double-blind, Active-controlled, Parallel-group, Multicenter, Proof-of-concep ...	Ulcerative Colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative col ...	Product Name: Guselkumab Product Code: CNTO1959 INN or Proposed INN: Guselkumab Trade Name: TREMFYA® Pro ...	Janssen-Cilag International NV	NULL	Not Recruiting	Female: yes Male: yes	210	Phase 2	United States;Mexico;Argentina;Poland;Brazil;Ukraine;Australia;Russian Federation;Germany
2	EUCTR2018-001510-15-PL (EUCTR)	01/03/2019	04/02/2019	A Proof-of-concept Study of the Efficacy and Safety of Combination Therapy With Guselkumab and Golim ...	A Phase 2a Randomized, Double-blind, Active-controlled, Parallel-group, Multicenter, Proof-of-concep ...	Ulcerative Colitis MedDRA version: 20.1;Level: LLT;Classification code 10045365;Term: Ulcerative col ...	Product Name: Guselkumab Product Code: CNTO1959 INN or Proposed INN: Guselkumab Trade Name: TREMFYA® Pro ...	Janssen-Cilag International NV	NULL	Not Recruiting	Female: yes Male: yes	210	Phase 2	United States;Mexico;Argentina;Brazil;Poland;Ukraine;Australia;Russian Federation;Germany
3	EUCTR2014-000656-29-BE (EUCTR)	13/06/2014	05/03/2014	Study to evaluate delivery preference of Simponi (golimumab) by Ulcerative Colitis patients: deliver ...	Preference for a prefilled syringe or Smartject™ device for delivering SIMPONI (golimumab) in patien ...	Ulcerative Colitis MedDRA version: 17.1;Level: LLT;Classification code 10045365;Term: Ulcerative col ...	Trade Name: Simponi®(Golimumab) Product Name: Simponi (Golimumab) Product Code: MK-8259 INN or Proposed ...	MSD Belgium BVBA/SPRL	NULL	Authorised-recruitment may be ongoing or finished	Female: yes Male: yes			Belgium

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271. Ankylosing spondylitis

Clinical trials : 563 / Drugs : 372 - (DrugBank : 72) / Drug target genes : 41 - Drug target pathways : 145

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No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT03557853 (ClinicalTrials.gov)	June 2016	5/6/2018	Clinical and Radiological Manifestations of Coxitis in Patients With Ankylosing Spondylitis Treated ...	A Prospective Observational Study to Evaluate Clinical and Radiological Manifestations of Coxitis in ...	Ankylosing Spondylitis;Coxitis	Drug: Golimumab Injection	MSD Pharmaceuticals LLC	NULL	Unknown status	18 Years	N/A	All	39		Russian Federation
2	NCT01313858 (ClinicalTrials.gov)	April 2010	10/3/2011	A Study to Investigate the Use of Golimumab (Simponi®) in Participants With Rheumatoid Arthritis, Ps ...	Non-Interventional Study Investigating the Use of Golimumab (Simponi®) in Patients With Rheumatoid A ...	Arthritis, Rheumatoid;Arthritis, Psoriatic;Spondylitis, Ankylosing	Drug: Simponi®;Drug: Methotrexate	Merck Sharp & Dohme Corp.	NULL	Completed	18 Years	N/A	All	1613	N/A	Germany

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