Corticotropin-releasing hormone ( DrugBank: Corticotropin, Corticotropin-releasing hormone )
2 diseases
| ID | Disease name (Link within this page) | Number of trials |
|---|---|---|
| 75 | Cushing disease | 2 |
| 205 | Fragile X syndrome related disease | 1 |
75. Cushing disease
Clinical trials : 203 / Drugs : 191 - (DrugBank : 51) / Drug target genes : 62 - Drug target pathways : 128
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT01459237 (ClinicalTrials.gov) | October 11, 2011 | 21/10/2011 | Effects of Hormone Stimulation on Brain Scans for Cushing s Disease | Prospective Evaluation of the Effect of Corticotropin-Releasing Hormone Stimulation on 18F-Fludeoxyglucose High-Resolution Positron-Emission Tomography in Cushing's Disease | Pituitary Neoplasm | Drug: Acthrel | National Institute of Neurological Disorders and Stroke (NINDS) | NULL | Completed | 8 Years | N/A | All | 30 | Early Phase 1 | United States |
| 2 | NCT00001180 (ClinicalTrials.gov) | March 1982 | 3/11/1999 | Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency | Dose Response Relationship for Single Doses of Corticotropin Releasing Hormone (CRH) in Normal Volunteers and in Patients With Adrenal Insufficiency | Adrenal Gland Hyperfunction;Adrenal Gland Hypofunction;Cushing's Syndrome;Healthy | Drug: Ovine Corticotropin-Releasing Hormone (oCRH) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | NULL | Completed | N/A | N/A | Both | 2250 | N/A | United States |
205. Fragile X syndrome related disease
Clinical trials : 5 / Drugs : 13 - (DrugBank : 7) / Drug target genes : 25 - Drug target pathways : 29
| No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NCT00033293 (ClinicalTrials.gov) | March 15, 2004 | 9/4/2002 | Cyclophosphamide and Prednisone With or Without Immunoglobulin in Treating Abnormal Muscle Movement in Children With Neuroblastoma | A Pilot Study Randomized Trial of Intravenous Gammaglobulin Therapy for Patients With Neuroblastoma Associated Opsoclonus-Myoclonus-Ataxia Syndrome Treated With Chemotherapy and Prednisone | Disseminated Neuroblastoma;Localized Resectable Neuroblastoma;Localized Unresectable Neuroblastoma;Regional Neuroblastoma;Stage 4S Neuroblastoma | Biological: therapeutic immune globulin;Other: clinical observation;Drug: cyclophosphamide;Drug: prednisone;Procedure: magnetic resonance imaging;Other: laboratory biomarker analysis;Drug: Corticotropin-Releasing Hormone | Children's Oncology Group | National Cancer Institute (NCI) | Active, not recruiting | N/A | 8 Years | All | 53 | Phase 3 | United States;Australia;Canada;Netherlands;New Zealand;Puerto Rico;Switzerland |