TPN171H ( DrugBank: - )

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1 disease

ID	Disease name (Link within this page)	Number of trials
86	Pulmonary arterial hypertension	2

86. Pulmonary arterial hypertension

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Clinical trials : 1,181 /  Drugs : 701 - (DrugBank : 126) / Drug target genes : 105 - Drug target pathways : 192

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT05208814 (ClinicalTrials.gov)	February 28, 2022	29/12/2021	a Study to Evaluate the Pharmacokinetics and Safety of TPN171H Tablets in Patients With Renal Insufficiency and Healthy Subjects	a Parallel, Open, Single-dose Administration Phase I Study to Evaluate the Pharmacokinetics and Safety of TPN171H Tablets in Patients With Renal Insufficiency and Healthy Subjects	Pulmonary Arterial Hypertension;Erectile Dysfunction	Drug: TPN171H single dose	Vigonvita Life Sciences	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	Not yet recruiting	18 Years	70 Years	All	56	Phase 1	NULL
2	NCT04483115 (ClinicalTrials.gov)	November 16, 2020	15/7/2020	Acute Haemodynamic Study of TPN171H in Patients With Pulmonary Arterial Hypertension	Multi-center, Randomized,Placebo and Positive Controlled Clinical Study of TPN171H Tablets on Acute Haemodynamics in Patients With Pulmonary Arterial Hypertension	Pulmonary Arterial Hypertension	Drug: TPN171H;Drug: Placebo;Drug: Tadalafil	Vigonvita Life Sciences	Shanghai Institute of Materia Medica, Chinese Academy of Sciences	Recruiting	18 Years	75 Years	All	60	Phase 2	China