RAAV2tYF-GRK1-hRPGRco ( DrugBank: - )


1 disease
IDDisease name (Link within this page)Number of trials
90Retinitis pigmentosa1

90. Retinitis pigmentosa


Clinical trials : 130 Drugs : 180 - (DrugBank : 41) / Drug target genes : 49 - Drug target pathways : 109
No.TrialIDDate_
enrollment
Date_
registration
Public_titleScientific_titleConditionInterventionPrimary_
sponsor
Secondary_
sponsor
Recruitment_
Status
Inclusion_
agemin
Inclusion_
agemax
Inclusion_
gender
Target_
size
PhaseCountries
1NCT04850118
(ClinicalTrials.gov)
August 20215/4/2021A Clinical Trial Evaluating the Safety and Efficacy of a Single Subretinal Injection of AGTC-501 in Participants With X-linked Retinitis Pigmentosa Caused by RPGR MutationsA Phase 2/3, Randomized, Controlled, Masked, Multi-center Study to Evaluate the Efficacy, Safety and Tolerability of Two Doses of AGTC-501, a Recombinant Adeno-associated Virus Vector Expressing RPGR (rAAV2tYF-GRK1-RPGR), Compared to an Untreated Control Group in Male Subjects With X-linked Retinitis Pigmentosa Confirmed by a Pathogenic Variant in the RPGR GeneX-Linked Retinitis PigmentosaBiological: rAAV2tYF-GRK1-hRPGRcoApplied Genetic Technologies CorpNULLNot yet recruiting8 Years50 YearsMale63Phase 2/Phase 3Israel;Netherlands;United States