RhNGF 180 µg/ml eye drops solution ( DrugBank: rhNGF )

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1 disease

ID	Disease name (Link within this page)	Number of trials
90	Retinitis pigmentosa	2

90. Retinitis pigmentosa

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Clinical trials : 130 /  Drugs : 180 - (DrugBank : 41) / Drug target genes : 49 - Drug target pathways : 109

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02609165 (ClinicalTrials.gov)	May 2015	12/10/2015	Nerve Growth Factor Eye Drops Treatment in Patients With Retinitis Pigmentosa and Cystoid Macular Edema	Nerve Growth Factor Eye Drops as a Novel Treatment for Vision Loss in Patients With Retinitis Pigmentosa: From Preclinical to Clinical Phase II Trial	Retinitis Pigmentosa;Cystoid Macular Edema	Drug: rhNGF 180 µg/ml eye drops solution;Drug: vehicle eye drops	Ospedale San Raffaele	Dompé Farmaceutici S.p.A	Completed	18 Years	N/A	All	45	Phase 2	Italy
2	NCT02110225 (ClinicalTrials.gov)	January 2014	8/4/2014	A Dose Ranging Study to Evaluate the Safety and Potential Efficacy of rhNGF in Patients With Retinitis Pigmentosa (RP)	A 24 Week Phase Ib/II, Multicenter, Randomized, Controlled, Parallel Group, Dose Ranging Study With a 24 Week Follow-up to Evaluate Safety and Potential Efficacy of 2 Doses (60, 180 µg/ml) of rhNGF Solution vs Vehicle in Patients With RP.	Retinitis Pigmentosa	Drug: rhNGF 60 µg/ml eye drops solution;Drug: rhNGF 180 µg/ml eye drops solution;Drug: Placebo	Dompé Farmaceutici S.p.A	NULL	Completed	18 Years	N/A	All	50	Phase 1/Phase 2	Italy