Drug（薬物リスト） DrugBank | All Description Patterns💬 Info on mouse-over

No.	薬物名（臨床試験情報から抽出）	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	指定難病告示番号
1	Acetylsalicylic acid	Acetylsalicylic acid	1件: D00109 💬	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	4件: 13, 46, 51, 210 💬
2	Act-064992	-	-	-	-	5件: 51, 85, 86, 88, 210 💬
3	Administration of an ace-inhibitor or not	-	-	-	-	1件: 210 💬
4	Aesculus hippocastanum / horse chestnut	Horse chestnut	-	-	-	1件: 210 💬
5	Ambrisentan	Ambrisentan	1件: D07077 💬	1件: EDNRA 💬	7件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Pathways in cancer, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	7件: 51, 84, 85, 86, 88, 210, 211 💬
6	Arginine	Arginine	1件: D02982 💬	-	-	9件: 46, 67, 78, 96, 97, 113, 210, 251, 299 💬
7	Aspirin	Acetylsalicylic acid	1件: D00109 💬	2件: PTGS1, PTGS2 💬	23件: Alzheimer disease, Arachidonic acid metabolism, C-type lectin receptor signaling pathway, Chemical carcinogenesis, Human cytomegalovirus infection, Human papillomavirus infection, IL-17 signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Metabolic pathways, MicroRNAs in cancer, NF-kappa B signaling pathway, Ovarian steroidogenesis, Oxytocin signaling pathway, Pathways in cancer, Pathways of neurodegeneration - multiple diseases, Platelet activation, Regulation of lipolysis in adipocytes, Retrograde endocannabinoid signaling, Serotonergic synapse, Small cell lung cancer, TNF signaling pathway, VEGF signaling pathway	11件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 210, 231 💬
8	Autologous tissue-engineered vascular graft	-	-	-	-	1件: 210 💬
9	Bay 59-7939	-	-	-	-	1件: 210 💬
10	Bosentan	Bosentan	2件: D01227, D07538 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬
11	Carvedilol	Carvedilol	2件: D00255, D03415 💬	5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 💬	12件: AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	5件:  6 , 57, 86, 113, 210 💬
12	Colchicine	Colchicine	1件: D00570 💬	9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 💬	10件: Alzheimer disease, Amyotrophic lateral sclerosis, Gap junction, Huntington disease, Parkinson disease, Pathogenic Escherichia coli infection, Pathways of neurodegeneration - multiple diseases, Phagosome, Prion disease, Salmonella infection	7件:  2 , 42, 46, 56, 93, 210, 266 💬
13	Digoxin	Digoxin	1件: D00298 💬	4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 💬	18件: Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Aldosterone-regulated sodium reabsorption, Bile secretion, Carbohydrate digestion and absorption, Cardiac muscle contraction, Endocrine and other factor-regulated calcium reabsorption, Gastric acid secretion, Insulin secretion, Mineral absorption, Pancreatic secretion, Protein digestion and absorption, Proximal tubule bicarbonate reclamation, Salivary secretion, Thyroid hormone signaling pathway, Thyroid hormone synthesis, cAMP signaling pathway, cGMP-PKG signaling pathway	3件:  8 , 46, 210 💬
14	Enalapril	Enalapril	2件: D00621, D07892 💬	1件: ACE 💬	6件: Chagas disease, Coronavirus disease - COVID-19, Diabetic cardiomyopathy, Hypertrophic cardiomyopathy, Renin secretion, Renin-angiotensin system	7件: 19, 46, 66, 113, 210, 222, 223 💬
15	Eplerenone	Eplerenone	1件: D01115 💬	1件: NR3C2 💬	1件: Aldosterone-regulated sodium reabsorption	4件: 75, 113, 210, 215 💬
16	Horse chestnut	Horse chestnut	-	-	-	1件: 210 💬
17	Jnj-39039039	-	-	-	-	1件: 210 💬
18	Liothyronine	Liothyronine	2件: D01011, D08128 💬	2件: THRA, THRB 💬	2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway	3件: 13, 210, 212 💬
19	Liothyronine i 131	Liothyronine	2件: D01011, D08128 💬	2件: THRA, THRB 💬	2件: Neuroactive ligand-receptor interaction, Thyroid hormone signaling pathway	2件: 210, 212 💬
20	Macitentan	Macitentan	1件: D10135 💬	2件: EDNRA, EDNRB 💬	9件: Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway	5件: 51, 85, 86, 88, 210 💬
21	Milk	Cow milk	-	-	-	2件: 98, 210 💬
22	Mpc	-	-	-	-	2件: 210, 211 💬
23	Mysildecard	-	-	-	-	1件: 210 💬
24	Mysildecard 20 mg	-	-	-	-	1件: 210 💬
25	Mz101	-	-	-	-	1件: 210 💬
26	Nitric oxide	Nitric Oxide	1件: D00074 💬	-	-	8件: 46, 85, 86, 98, 210, 251, 294, 299 💬
27	Normal saline	-	-	-	-	16件:  6 , 17, 22, 36, 46, 49, 60, 70, 94, 96, 210, 211, 226, 276, 296, 299 💬
28	Odsh at 0.125 mg/kg/h	-	-	-	-	1件: 210 💬
29	Odsh at 0.250 mg/kg/h	-	-	-	-	1件: 210 💬
30	Odsh at 0.375 mg/kg/h	-	-	-	-	1件: 210 💬
31	Opsumit	-	-	-	-	3件: 86, 88, 210 💬
32	Opsumit®	-	-	-	-	3件: 86, 88, 210 💬
33	Other: human milk derived fortifier	Cow milk	-	-	-	1件: 210 💬
34	Other: human/bovine milk	Cow milk	-	-	-	1件: 210 💬
35	Rexlemestrocel-l	-	-	-	-	2件: 210, 211 💬
36	Rivaroxaban	Rivaroxaban	1件: D07086 💬	1件: F10 💬	1件: Complement and coagulation cascades	5件: 46, 49, 75, 91, 210 💬
37	Scrm001_tevg	-	-	-	-	1件: 210 💬
38	Sildenafil	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	17件:  6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬
39	Sildenafil by injection	Sildenafil	2件: D02229, D08514 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 210 💬
40	Spironolactone	Spironolactone	1件: D00443 💬	1件: NR3C2 💬	1件: Aldosterone-regulated sodium reabsorption	7件: 58, 67, 86, 113, 210, 218, 225 💬
41	Spironolactone (drug)	Spironolactone	1件: D00443 💬	1件: NR3C2 💬	1件: Aldosterone-regulated sodium reabsorption	1件: 210 💬
42	Sugar pill	-	-	-	-	8件:  5 ,  6 , 49, 67, 70, 86, 206, 210 💬
43	Tadalafil	Tadalafil	1件: D02008 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	7件:  6 , 51, 75, 84, 86, 113, 210 💬
44	Tadalafil citrate	Tadalafil	1件: D02008 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	1件: 210 💬
45	Tracleer	-	-	-	-	8件: 13, 51, 84, 85, 86, 88, 210, 211 💬
46	Treprostinil	Treprostinil	1件: D06213 💬	1件: PTGIR 💬	3件: Neuroactive ligand-receptor interaction, Platelet activation, Vascular smooth muscle contraction	6件: 51, 84, 85, 86, 88, 210 💬
47	Udenafil	Udenafil	1件: D10027 💬	1件: PDE5A 💬	3件: Metabolic pathways, Purine metabolism, cGMP-PKG signaling pathway	2件: 86, 210 💬
48	Vasopressin	Vasopressin	1件: D00101 💬	3件: AVPR1A, AVPR1B, AVPR2 💬	5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption	1件: 210 💬
49	Vasopressin, arginine	Arginine	2件: D00101, D02982 💬	3件: AVPR1A, AVPR1B, AVPR2 💬	5件: Calcium signaling pathway, Neuroactive ligand-receptor interaction, Phospholipase D signaling pathway, Vascular smooth muscle contraction, Vasopressin-regulated water reabsorption	1件: 210 💬
50	Vitamin c	Ascorbic acid	1件: D00018 💬	-	-	6件: 10, 192, 206, 210, 211, 212 💬
51	Xarelto	-	-	-	-	2件: 49, 210 💬

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