Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
2 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
3 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
4 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
5 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
6 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
7 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
8 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
9 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
10 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
11 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
12 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
13 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
14 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
15 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
16 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
17 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
18 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
19 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
20 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
21 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
22 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
23 | Autoimmune thyroid disease 💬 41 genes, 14 drugs (DrugBank) and 37 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
24 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
25 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
26 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
27 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
28 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
29 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
IL1A 1件: IL1A 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
30 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
31 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
32 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
33 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
34 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
35 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
JAK2 2件: JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
36 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
37 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
38 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
SERPINC1 1件: SERPINC1 💬 |
D07510 D07510 💬 |
Heparin | 060 11件: 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 💬 |
39 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
40 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
41 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
42 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
43 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
44 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
45 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
46 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
47 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
48 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
49 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
50 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
51 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
52 | Cytosolic DNA-sensing pathway 💬 16 genes, 10 drugs (DrugBank) and 25 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
53 | Cytosolic DNA-sensing pathway 💬 16 genes, 10 drugs (DrugBank) and 25 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
54 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
55 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
56 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
57 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
58 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
59 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
60 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
61 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
62 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
63 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
64 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
65 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
66 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
67 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
68 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
69 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
70 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
71 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
72 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
73 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
74 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
75 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
76 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
77 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
78 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
79 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
80 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
81 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
82 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
83 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
84 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
85 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
86 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
87 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
88 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
89 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
90 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
91 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
92 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
93 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
94 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
95 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
96 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
97 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 1件: JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
98 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
99 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
100 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
101 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
102 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 2件: JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
103 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
104 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
105 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
106 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
107 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
108 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
109 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
110 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
111 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
112 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
113 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
114 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
115 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
116 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
117 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
118 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
119 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
120 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
121 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
122 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
123 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
124 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
125 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
126 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
127 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
128 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
129 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
130 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
131 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
132 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
133 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
134 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
135 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
136 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
137 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
138 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
139 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
140 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
141 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
142 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
143 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
144 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
145 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
146 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
147 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
148 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
149 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
150 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
151 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
152 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
153 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
154 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
155 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
156 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
157 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
158 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
159 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
160 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
161 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
162 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
163 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
164 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
165 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
166 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
167 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
168 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
169 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
170 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
171 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
172 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
173 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
174 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
175 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
176 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
177 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
178 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
179 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
180 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
181 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
182 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
183 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
184 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
185 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
186 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
187 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
188 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
189 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
190 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
191 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
192 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
193 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
194 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
195 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
196 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
197 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
198 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
199 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 17 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
200 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
201 | Renin-angiotensin system 💬 6 genes, 21 drugs (DrugBank) and 32 diseases |
ACE 1件: ACE 💬 |
D00251 D00251 💬 |
Captopril | 006 8件: 6 , 17, 46, 86, 96, 97, 107, 271 💬 |
202 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
203 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
204 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
205 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
206 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
207 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
208 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
209 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
210 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
211 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
212 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
213 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
214 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
215 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
216 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
217 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
218 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
219 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
220 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
221 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
222 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
223 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
224 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
225 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
226 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
227 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
228 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
229 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
230 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
231 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
232 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
233 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
234 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
235 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
236 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
CD86 1件: CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
237 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
238 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
239 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
240 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
241 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
242 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
243 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
244 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
IFNG 1件: IFNG 💬 |
D11120 D11120 💬 |
Emapalumab | 107 1件: 107 💬 |
245 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
IL1A 2件: IL1A, IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |
246 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
247 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
248 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 2件: JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
249 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
CD80 2件: CD80, CD86 💬 |
D03203 D03203 💬 |
Abatacept | 011 26件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 95, 96, 97, 107, 160, 164, 222, 271, 284, 285, 300 💬 |
250 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL6R 1件: IL6R 💬 |
D10161 D10161 💬 |
Sarilumab | 041 5件: 41, 46, 84, 107, 271 💬 |
251 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
252 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
D09315 D09315 💬 |
Canakinumab | 046 10件: 46, 56, 84, 106, 107, 108, 113, 266, 267, 269 💬 |
253 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
IL1B 1件: IL1B 💬 |
D06635 D06635 💬 |
Rilonacept | 051 4件: 51, 106, 107, 266 💬 |