Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
2 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
3 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
4 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
5 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
6 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
7 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
8 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
9 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
10 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
11 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
12 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
13 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
14 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
15 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
16 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
17 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
18 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
19 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
20 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
21 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
22 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
23 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
24 | Autophagy - other 💬 1 gene, 3 drugs (DrugBank) and 41 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
25 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
26 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
27 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
28 | Cell adhesion molecules 💬 32 genes, 19 drugs (DrugBank) and 37 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
29 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
30 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
31 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
32 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
33 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
34 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
35 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
ACVR2A 2件: ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 1件: 15 💬 |
36 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
37 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
38 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
39 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
40 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
41 | ECM-receptor interaction 💬 6 genes, 9 drugs (DrugBank) and 14 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
42 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
43 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
44 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
45 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
46 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
47 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
ACVR2A 2件: ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 1件: 15 💬 |
48 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
49 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
50 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
51 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
52 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
53 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
54 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
55 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
56 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
57 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
58 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
59 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
60 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
61 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
62 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
63 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
64 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
65 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
66 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
67 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
68 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
69 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
70 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
71 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
72 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
IL1R1 2件: IL1R1, IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
73 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
74 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
75 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
76 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
77 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
78 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
79 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
80 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
81 | Inflammatory mediator regulation of TRP channels 💬 22 genes, 38 drugs (DrugBank) and 55 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
82 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
83 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
84 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
85 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
86 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
87 | Intestinal immune network for IgA production 💬 27 genes, 23 drugs (DrugBank) and 47 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
88 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
89 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
90 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
91 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
92 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
93 | Leukocyte transendothelial migration 💬 12 genes, 11 drugs (DrugBank) and 25 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
94 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
95 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
96 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
97 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
98 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
99 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
100 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
101 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
102 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
103 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
104 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
105 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
106 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
107 | Neutrophil extracellular trap formation 💬 32 genes, 27 drugs (DrugBank) and 56 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
108 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
109 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
110 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
111 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
112 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
113 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
114 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
115 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
116 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
117 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
118 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
119 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
120 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
121 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
122 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
123 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
124 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
125 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
126 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
127 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
128 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
129 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
130 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
131 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
132 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
133 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
134 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
135 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
136 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
137 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
138 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
139 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
140 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
141 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
142 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
143 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
ACVR2A 2件: ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 1件: 15 💬 |
144 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
145 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
146 | Synaptic vesicle cycle 💬 7 genes, 29 drugs (DrugBank) and 37 diseases |
SNAP25 1件: SNAP25 💬 |
D00783 D00783 💬 |
Botulinum toxin type A | 002 13件: 2 , 5 , 6 , 7 , 13, 15, 17, 36, 51, 70, 113, 149, 226 💬 |
147 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
148 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
149 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
150 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
ACVR2A 2件: ACVR2A, ACVR2B 💬 |
D10620 D10620 💬 |
Bimagrumab | 015 1件: 15 💬 |
151 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
152 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL1R1 1件: IL1R1 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
153 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
154 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
155 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
156 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
157 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
158 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
159 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
160 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
161 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
162 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
163 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IL1R2 1件: IL1R2 💬 |
D02934 D02934 💬 |
Anakinra | 002 19件: 2 , 13, 15, 19, 28, 37, 41, 46, 49, 50, 56, 65, 84, 86, 97, 106, 107, 266, 299 💬 |
164 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
165 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
166 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
167 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
168 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
MTOR 1件: MTOR 💬 |
D00753 D00753 💬 |
Sirolimus | 002 40件: 2 , 6 , 13, 15, 17, 19, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 84, 85, 86, 89, 96, 98, 127, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 💬 |
169 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
170 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
LTA 2件: LTA, TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |
171 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
ITGA4 1件: ITGA4 💬 |
D06886 D06886 💬 |
Natalizumab | 013 6件: 13, 15, 25, 46, 63, 96 💬 |
172 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D00742 D00742 💬 |
Etanercept | 015 15件: 15, 28, 35, 38, 39, 46, 50, 53, 56, 60, 85, 228, 271, 285, 298 💬 |