Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
2 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
3 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
ALPL 1件: ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 1件: 172 💬 |
4 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
5 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
6 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
ALPL 1件: ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 1件: 172 💬 |
7 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
8 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
9 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
ALPL 1件: ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 1件: 172 💬 |
10 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
11 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
12 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
13 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
14 | Thiamine metabolism 💬 1 gene, 1 drug (DrugBank) and 1 disease |
ALPL 1件: ALPL 💬 |
D10595 D10595 💬 |
Asfotase alfa | 172 1件: 172 💬 |