Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over

32 / 286 pathways

No. KEGG PATHWAY
On map, Yellow: Drug target, Red: All disease-related
KEGG GENES KEGG DRUG DrugBank 指定難病告示番号
1 ABC transporters 💬
1件: ABCC8 💬 D00418 💬 Minoxidil 1件: 179 💬
2 Adrenergic signaling in cardiomyocytes 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
3 Adrenergic signaling in cardiomyocytes 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
4 AGE-RAGE signaling pathway in diabetic complications 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
5 AGE-RAGE signaling pathway in diabetic complications 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
6 Alcoholism 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
7 Alcoholism 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
8 Alcoholism 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
9 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
10 Aldosterone synthesis and secretion 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
11 Amphetamine addiction 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
12 Amphetamine addiction 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
13 Apelin signaling pathway 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
14 Apelin signaling pathway 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
15 Calcium signaling pathway 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
16 Calcium signaling pathway 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
17 Calcium signaling pathway 💬
1件: HTR2A 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
18 cAMP signaling pathway 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
19 cGMP-PKG signaling pathway 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
20 cGMP-PKG signaling pathway 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
21 Cocaine addiction 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
22 Cocaine addiction 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
23 Cocaine addiction 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
24 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
25 Coronavirus disease - COVID-19 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
26 Cortisol synthesis and secretion 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
27 Cortisol synthesis and secretion 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
28 Cushing syndrome 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
29 Cushing syndrome 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
30 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
31 Diabetic cardiomyopathy 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
32 Dopaminergic synapse 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
33 Dopaminergic synapse 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
34 Dopaminergic synapse 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
35 Gap junction 💬
2件: DRD2, HTR2A 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
36 GnRH secretion 💬
1件: KCNJ11 💬 D00418 💬 Minoxidil 1件: 179 💬
37 Inflammatory mediator regulation of TRP channels 💬
1件: HTR2A 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
38 Insulin secretion 💬
2件: ABCC8, KCNJ11 💬 D00418 💬 Minoxidil 1件: 179 💬
39 Neuroactive ligand-receptor interaction 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
40 Neuroactive ligand-receptor interaction 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
41 Neuroactive ligand-receptor interaction 💬
2件: DRD2, HTR2A 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
42 Parkinson disease 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
43 Parkinson disease 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
44 Parkinson disease 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
45 Pathways in cancer 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
46 Pathways in cancer 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
47 Pathways of neurodegeneration - multiple diseases 💬
1件: SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
48 Pathways of neurodegeneration - multiple diseases 💬
1件: SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
49 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
50 Phospholipase D signaling pathway 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
51 Rap1 signaling pathway 💬
1件: DRD2 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
52 Renin secretion 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
53 Renin secretion 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
54 Renin-angiotensin system 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
55 Renin-angiotensin system 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
56 Serotonergic synapse 💬
1件: HTR2A 💬 D00426 💬 Risperidone 5件:  8 , 156, 179, 187, 206 💬
57 Serotonergic synapse 💬
1件: SLC6A4 💬 D00326 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬
58 Serotonergic synapse 💬
1件: SLC6A4 💬 D00823 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬
59 Synaptic vesicle cycle 💬
2件: SLC6A2, SLC6A3 💬 D01296 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
60 Synaptic vesicle cycle 💬
2件: SLC6A2, SLC6A3 💬 D04999 💬 Methylphenidate 7件:  6 , 13, 34, 84, 113, 179, 206 💬
61 Synaptic vesicle cycle 💬
1件: SLC6A4 💬 D00326 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬
62 Synaptic vesicle cycle 💬
1件: SLC6A4 💬 D00823 💬 Fluoxetine 6件: 13, 17, 78, 86, 179, 206 💬
63 Type II diabetes mellitus 💬
2件: ABCC8, KCNJ11 💬 D00418 💬 Minoxidil 1件: 179 💬
64 Vascular smooth muscle contraction 💬
1件: AGTR1 💬 D00357 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬
65 Vascular smooth muscle contraction 💬
1件: AGTR1 💬 D08146 💬 Losartan 18件: 17, 19, 36, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 💬