Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | ABC transporters 💬 2 genes, 9 drugs (DrugBank) and 6 diseases |
ABCC8 1件: ABCC8 💬 |
D00294 D00294 💬 |
Diazoxide | 013 2件: 13, 193 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
3 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
4 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
5 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
CACNA1C 5件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, SCN5A 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
6 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
7 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
8 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
9 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
CACNA1C 6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
10 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
GRIA1 2件: GRIA1, GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
11 | Arrhythmogenic right ventricular cardiomyopathy 💬 11 genes, 24 drugs (DrugBank) and 28 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
12 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
CA2 1件: CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
13 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
14 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
15 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
16 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
17 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
OXTR 1件: OXTR 💬 |
D07229 D07229 💬 |
Carbetocin | 193 1件: 193 💬 |
18 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 5件: 6 , 127, 193, 206, 226 💬 |
19 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
20 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
21 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
22 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
CACNA1C 8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
23 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 4件: 6 , 17, 193, 233 💬 |
24 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
25 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
26 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
OXTR 1件: OXTR 💬 |
D07229 D07229 💬 |
Carbetocin | 193 1件: 193 💬 |
27 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 5件: 6 , 127, 193, 206, 226 💬 |
28 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
29 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
SSTR2 1件: SSTR2 💬 |
D06495 D06495 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
30 | Carbohydrate digestion and absorption 💬 10 genes, 16 drugs (DrugBank) and 28 diseases |
CACNA1D 1件: CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
31 | Cardiac muscle contraction 💬 12 genes, 16 drugs (DrugBank) and 25 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
32 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
CACNA1D 1件: CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
33 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA2A 1件: ADRA2A 💬 |
D00606 D00606 💬 |
Guanfacine | 193 1件: 193 💬 |
34 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA2A 1件: ADRA2A 💬 |
D08031 D08031 💬 |
Guanfacine | 193 1件: 193 💬 |
35 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
36 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
37 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
38 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
39 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
40 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
CACNA1C 6件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
41 | Cocaine addiction 💬 14 genes, 58 drugs (DrugBank) and 47 diseases |
GRIA2 1件: GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
42 | Collecting duct acid secretion 💬 3 genes, 11 drugs (DrugBank) and 32 diseases |
CA2 1件: CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
43 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
44 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
45 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
CYP11B1 1件: CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
46 | Cortisol synthesis and secretion 💬 14 genes, 30 drugs (DrugBank) and 62 diseases |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
47 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
48 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
49 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
CYP11B1 1件: CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
50 | Cushing syndrome 💬 21 genes, 43 drugs (DrugBank) and 66 diseases |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
51 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
52 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
53 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
54 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
55 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
56 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
CACNA1C 7件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, SCN1A 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
57 | GABAergic synapse 💬 28 genes, 37 drugs (DrugBank) and 54 diseases |
CACNA1C 20件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
58 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
59 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
60 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
61 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
CA2 1件: CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
62 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
63 | Gastric acid secretion 💬 12 genes, 45 drugs (DrugBank) and 49 diseases |
SSTR2 1件: SSTR2 💬 |
D06495 D06495 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
64 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
CACNA1C 11件: CACNA1C, CACNA1D, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
65 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
66 | GnRH secretion 💬 19 genes, 36 drugs (DrugBank) and 53 diseases |
KCNJ11 1件: KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 2件: 13, 193 💬 |
67 | GnRH signaling pathway 💬 15 genes, 33 drugs (DrugBank) and 38 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
68 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
69 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
70 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
71 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
SSTR2 1件: SSTR2 💬 |
D06495 D06495 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
72 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
GRIA1 4件: GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
73 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
74 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 2件: 13, 193 💬 |
75 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
76 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 4件: 6 , 17, 193, 233 💬 |
77 | Insulin secretion 💬 13 genes, 40 drugs (DrugBank) and 43 diseases |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
78 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
79 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
80 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
CACNA1C 3件: CACNA1C, GRIA1, GRIA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
81 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
82 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CA2 2件: CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
83 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
84 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CYP11B1 1件: CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
85 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
CYP19A1 1件: CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 3件: 78, 86, 193 💬 |
86 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
GABRA1 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
87 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA2A 1件: ADRA2A 💬 |
D00606 D00606 💬 |
Guanfacine | 193 1件: 193 💬 |
88 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA2A 1件: ADRA2A 💬 |
D08031 D08031 💬 |
Guanfacine | 193 1件: 193 💬 |
89 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
90 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
91 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
92 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 1件: CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 1件: 193 💬 |
93 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
CNR1 2件: CNR1, CNR2 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
94 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GABRA1 25件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
95 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
96 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GLP1R 1件: GLP1R 💬 |
D04121 D04121 💬 |
Exenatide | 006 4件: 6 , 17, 193, 233 💬 |
97 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GLP1R 1件: GLP1R 💬 |
D06404 D06404 💬 |
Liraglutide | 006 3件: 6 , 75, 193 💬 |
98 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
HRH3 1件: HRH3 💬 |
D10749 D10749 💬 |
Pitolisant | 006 2件: 6 , 193 💬 |
99 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
MC2R 1件: MC2R 💬 |
D00146 D00146 💬 |
Corticotropin | 002 13件: 2 , 13, 14, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 💬 |
100 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OXTR 1件: OXTR 💬 |
D07229 D07229 💬 |
Carbetocin | 193 1件: 193 💬 |
101 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 5件: 6 , 127, 193, 206, 226 💬 |
102 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
SSTR2 1件: SSTR2 💬 |
D00442 D00442 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
103 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
SSTR2 1件: SSTR2 💬 |
D06495 D06495 💬 |
Octreotide | 067 7件: 67, 75, 84, 85, 89, 193, 227 💬 |
104 | Nicotine addiction 💬 30 genes, 32 drugs (DrugBank) and 40 diseases |
GABRA1 20件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
105 | Nitrogen metabolism 💬 14 genes, 5 drugs (DrugBank) and 16 diseases |
CA2 2件: CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
106 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
CYP19A1 1件: CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 3件: 78, 86, 193 💬 |
107 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
108 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
OXTR 1件: OXTR 💬 |
D07229 D07229 💬 |
Carbetocin | 193 1件: 193 💬 |
109 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
OXTR 1件: OXTR 💬 |
D00089 D00089 💬 |
Oxytocin | 006 5件: 6 , 127, 193, 206, 226 💬 |
110 | Pancreatic secretion 💬 10 genes, 34 drugs (DrugBank) and 33 diseases |
CA2 1件: CA2 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
111 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CACNA1C 8件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
112 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
113 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
114 | Proximal tubule bicarbonate reclamation 💬 6 genes, 6 drugs (DrugBank) and 17 diseases |
CA2 2件: CA2, CA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
115 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 1件: CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
116 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
CNR1 1件: CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 1件: 193 💬 |
117 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
118 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
119 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
120 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
121 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
122 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
123 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
124 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CACNA1C 24件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ, GRIA1, GRIA2, GRIA3, GRIA4 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
125 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 1件: CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
126 | Retrograde endocannabinoid signaling 💬 33 genes, 61 drugs (DrugBank) and 62 diseases |
CNR1 1件: CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 1件: 193 💬 |
127 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB1 1件: ADRB1 💬 |
D00601 D00601 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
128 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB1 1件: ADRB1 💬 |
D02358 D02358 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
129 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRB1 1件: ADRB1 💬 |
D05011 D05011 💬 |
Metoprolol | 017 6件: 17, 57, 58, 113, 193, 226 💬 |
130 | Serotonergic synapse 💬 37 genes, 105 drugs (DrugBank) and 73 diseases |
CACNA1C 7件: CACNA1C, CACNA1D, CACNA1F, CACNA1S, GABRB1, GABRB2, GABRB3 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
131 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
GRIA1 3件: GRIA1, GRIA2, GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
132 | Steroid hormone biosynthesis 💬 7 genes, 10 drugs (DrugBank) and 14 diseases |
CYP11B1 1件: CYP11B1 💬 |
D00410 D00410 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
133 | Steroid hormone biosynthesis 💬 7 genes, 10 drugs (DrugBank) and 14 diseases |
CYP11B1 1件: CYP11B1 💬 |
D05019 D05019 💬 |
Metyrapone | 075 2件: 75, 193 💬 |
134 | Steroid hormone biosynthesis 💬 7 genes, 10 drugs (DrugBank) and 14 diseases |
CYP19A1 1件: CYP19A1 💬 |
D00960 D00960 💬 |
Anastrozole | 078 3件: 78, 86, 193 💬 |
135 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
CACNA1C 10件: CACNA1C, GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, SCN2A, SCN3A, SCN9A 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
136 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 1件: CNR1 💬 |
D10915 D10915 💬 |
Cannabidiol | 002 19件: 2 , 6 , 8 , 13, 36, 46, 95, 96, 97, 140, 144, 145, 156, 157, 158, 193, 206, 226, 271 💬 |
137 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
CNR1 1件: CNR1 💬 |
D05731 D05731 💬 |
Rimonabant | 193 1件: 193 💬 |
138 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
CACNA1D 1件: CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
139 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
GRIA3 1件: GRIA3 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
140 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
ABCC8 2件: ABCC8, KCNJ11 💬 |
D00294 D00294 💬 |
Diazoxide | 013 2件: 13, 193 💬 |
141 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
CACNA1C 2件: CACNA1C, CACNA1D 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |
142 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
CACNA1C 4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S 💬 |
D00537 D00537 💬 |
Topiramate | 006 5件: 6 , 140, 144, 156, 193 💬 |