Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
2 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
3 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
4 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
5 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
6 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
7 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
8 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
9 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
10 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A 1件: PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
11 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
12 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
13 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
14 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A 1件: PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
15 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
16 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
17 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
18 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
19 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
20 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
21 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
22 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
23 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
24 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
25 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone hemisuccinate | 013 7件: 13, 49, 50, 51, 53, 97, 211 💬 |
26 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D00462 D00462 💬 |
Oxandrolone | 211 2件: 211, 285 💬 |
27 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D00462 D00462 💬 |
Oxandrolone | 211 2件: 211, 285 💬 |
28 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
29 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
30 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
31 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D00462 D00462 💬 |
Oxandrolone | 211 2件: 211, 285 💬 |
32 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A 1件: PDE5A 💬 |
D02229 D02229 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
33 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE5A 1件: PDE5A 💬 |
D08514 D08514 💬 |
Sildenafil | 006 17件: 6 , 46, 50, 51, 85, 86, 90, 113, 210, 211, 212, 225, 226, 278, 294, 299, 301 💬 |
34 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
35 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
36 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
37 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
38 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
39 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
40 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
41 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |