Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
2 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
3 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
4 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
LEPR 1件: LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 1件: 265 💬 |
5 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
6 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
7 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
8 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
9 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
10 | Alcoholism 💬 28 genes, 69 drugs (DrugBank) and 52 diseases |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
11 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
PDE2A 1件: PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
12 | Aldosterone synthesis and secretion 💬 18 genes, 34 drugs (DrugBank) and 64 diseases |
PDE2A 1件: PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
13 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
14 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
15 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
16 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
17 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
18 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
19 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
20 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
LEPR 1件: LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 1件: 265 💬 |
21 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
22 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
23 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
24 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
25 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
26 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
27 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
28 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
29 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
30 | Apelin signaling pathway 💬 12 genes, 26 drugs (DrugBank) and 66 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
31 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
32 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
33 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
34 | Autophagy - animal 💬 13 genes, 15 drugs (DrugBank) and 57 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
35 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
36 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
37 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
38 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
39 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
40 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
NR1H4 1件: NR1H4 💬 |
D10699 D10699 💬 |
Cholic Acid | 020 4件: 20, 234, 265, 310 💬 |
41 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
NR1H4 1件: NR1H4 💬 |
D09360 D09360 💬 |
Obeticholic acid | 093 3件: 93, 265, 296 💬 |
42 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
43 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
44 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADORA2A 2件: ADORA2A, PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
45 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADORA2A 2件: ADORA2A, PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
46 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
47 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
ADORA1 8件: ADORA1, ADORA2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
48 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
49 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
50 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADORA1 5件: ADORA1, PDE2A, PDE3A, PDE3B, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
51 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
52 | Cholesterol metabolism 💬 5 genes, 7 drugs (DrugBank) and 4 diseases |
APOC3 1件: APOC3 💬 |
D11648 D11648 💬 |
Volanesorsen | 265 1件: 265 💬 |
53 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
54 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 21 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
55 | Circadian rhythm 💬 2 genes, 1 drug (DrugBank) and 21 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
56 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
57 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
58 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR 1件: GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
59 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
60 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
LEPR 1件: LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 1件: 265 💬 |
61 | Diabetic cardiomyopathy 💬 21 genes, 38 drugs (DrugBank) and 72 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
62 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
63 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
64 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
65 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
66 | Endocrine resistance 💬 19 genes, 37 drugs (DrugBank) and 59 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
67 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
68 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
69 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
70 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
71 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
72 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
73 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
74 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
75 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
76 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
77 | FoxO signaling pathway 💬 24 genes, 34 drugs (DrugBank) and 53 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
78 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
79 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
80 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
81 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
82 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
83 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
84 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
85 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
86 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR 1件: GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
87 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
88 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHRHR 1件: GHRHR 💬 |
D06655 D06655 💬 |
Tesamorelin | 078 2件: 78, 265 💬 |
89 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
90 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
91 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
92 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
93 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
94 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
95 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
96 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
97 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
98 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
99 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
100 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
101 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
102 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
103 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
104 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
105 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
106 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
107 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
108 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
109 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
110 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
111 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
112 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
113 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
114 | Insulin signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 59 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
115 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
116 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR 1件: GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
117 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
118 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
119 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
LEPR 1件: LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 1件: 265 💬 |
120 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
121 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
122 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
123 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
124 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
125 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
126 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
127 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
128 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
129 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
130 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
131 | Longevity regulating pathway 💬 10 genes, 16 drugs (DrugBank) and 61 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
132 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
133 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
134 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
135 | Longevity regulating pathway - multiple species 💬 10 genes, 13 drugs (DrugBank) and 56 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
136 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
137 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
138 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
139 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
140 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
141 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
142 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
143 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
144 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
145 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
146 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
147 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
148 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
149 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
ADORA1 9件: ADORA1, PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
150 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
151 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
152 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
153 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
154 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
155 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADORA1 2件: ADORA1, ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
156 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADORA1 2件: ADORA1, ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
157 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR 1件: GHR 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
158 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR 1件: GHR 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
159 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
160 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHRHR 1件: GHRHR 💬 |
D06655 D06655 💬 |
Tesamorelin | 078 2件: 78, 265 💬 |
161 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
LEPR 1件: LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 1件: 265 💬 |
162 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
MC4R 1件: MC4R 💬 |
D11927 D11927 💬 |
Setmelanotide | 202 2件: 202, 265 💬 |
163 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
164 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
LEPR 1件: LEPR 💬 |
D05014 D05014 💬 |
Metreleptin | 265 1件: 265 💬 |
165 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
166 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
167 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
168 | Olfactory transduction 💬 4 genes, 3 drugs (DrugBank) and 12 diseases |
PDE1B 2件: PDE1B, PDE2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
169 | Olfactory transduction 💬 4 genes, 3 drugs (DrugBank) and 12 diseases |
PDE1B 2件: PDE1B, PDE2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
170 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
171 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
172 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
173 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
174 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
175 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
AR 1件: AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
176 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
177 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
178 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
179 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
180 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
181 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
182 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
183 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
184 | Ovarian steroidogenesis 💬 6 genes, 34 drugs (DrugBank) and 47 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
185 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
186 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
187 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
188 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
189 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PDE4A 4件: PDE4A, PDE4B, PDE4C, PDE4D 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
190 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
191 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
192 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
193 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
194 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
195 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
196 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
197 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
AR 1件: AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
198 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
199 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
200 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
201 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
202 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
203 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
204 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
205 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
206 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
207 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR 2件: GHR, IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
208 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR 2件: GHR, IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
209 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
210 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
211 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
212 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
APOC3 1件: APOC3 💬 |
D11648 D11648 💬 |
Volanesorsen | 265 1件: 265 💬 |
213 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARA 1件: PPARA 💬 |
D00565 D00565 💬 |
Fenofibrate | 008 5件: 8 , 79, 93, 94, 265 💬 |
214 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
215 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
216 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
217 | PPAR signaling pathway 💬 10 genes, 12 drugs (DrugBank) and 30 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
218 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
219 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
220 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B 1件: PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
221 | Progesterone-mediated oocyte maturation 💬 14 genes, 32 drugs (DrugBank) and 37 diseases |
PDE3B 1件: PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
222 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
JAK2 1件: JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
223 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D00075 D00075 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
224 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D00957 D00957 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
225 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D00958 D00958 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
226 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D00959 D00959 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
227 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D06085 D06085 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
228 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
AR 1件: AR 💬 |
D06087 D06087 💬 |
Testosterone | 001 8件: 1 , 2 , 3 , 13, 60, 78, 113, 265 💬 |
229 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
230 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
231 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
232 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
233 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
234 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
PDE1B 9件: PDE1B, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE5A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
235 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
236 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
237 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
238 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
239 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
240 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
241 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADORA1 2件: ADORA1, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
242 | Regulation of lipolysis in adipocytes 💬 13 genes, 65 drugs (DrugBank) and 61 diseases |
ADORA1 2件: ADORA1, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
243 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
244 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
ADORA1 4件: ADORA1, PDE1B, PDE3A, PDE3B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
245 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
246 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
247 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
248 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ADORA1 1件: ADORA1 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
249 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
ADORA1 1件: ADORA1 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
250 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
PDE1B 1件: PDE1B 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
251 | Taste transduction 💬 30 genes, 78 drugs (DrugBank) and 65 diseases |
PDE1B 1件: PDE1B 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
252 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
253 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
254 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D00893 D00893 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
255 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D08410 D08410 💬 |
Pravastatin | 013 9件: 13, 46, 49, 67, 79, 96, 164, 265, 333 💬 |
256 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
257 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
258 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
259 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
260 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
261 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
262 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
263 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
264 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
265 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
266 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
267 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
268 | Thyroid cancer 💬 8 genes, 12 drugs (DrugBank) and 25 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
269 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D00944 D00944 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
270 | Tight junction 💬 10 genes, 26 drugs (DrugBank) and 40 diseases |
PRKAA1 2件: PRKAA1, PRKAA2 💬 |
D04966 D04966 💬 |
Metformin | 002 21件: 2 , 6 , 13, 46, 49, 60, 67, 75, 77, 81, 86, 113, 127, 158, 206, 225, 233, 265, 285, 299, 301 💬 |
271 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
272 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IGF1R 1件: IGF1R 💬 |
D03297 D03297 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
273 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
IGF1R 1件: IGF1R 💬 |
D04870 D04870 💬 |
Mecasermin | 065 6件: 65, 78, 96, 168, 265, 299 💬 |
274 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG 1件: PPARG 💬 |
D00945 D00945 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
275 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG 1件: PPARG 💬 |
D08378 D08378 💬 |
Pioglitazone | 002 17件: 2 , 6 , 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 💬 |
276 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG 1件: PPARG 💬 |
D00596 D00596 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
277 | Transcriptional misregulation in cancer 💬 24 genes, 43 drugs (DrugBank) and 71 diseases |
PPARG 1件: PPARG 💬 |
D08491 D08491 💬 |
Rosiglitazone | 046 5件: 46, 75, 97, 222, 265 💬 |
278 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |
279 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADORA2A 1件: ADORA2A 💬 |
D00528 D00528 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
280 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADORA2A 1件: ADORA2A 💬 |
D01453 D01453 💬 |
Caffeine | 002 9件: 2 , 6 , 13, 21, 46, 78, 96, 97, 265 💬 |
281 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 1件: JAK1 💬 |
D10308 D10308 💬 |
Baricitinib | 041 9件: 41, 46, 49, 50, 93, 107, 265, 268, 325 💬 |