Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adherens junction 💬 9 genes, 18 drugs (DrugBank) and 24 diseases |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
2 | Bladder cancer 💬 9 genes, 19 drugs (DrugBank) and 23 diseases |
FGFR3 1件: FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
3 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
4 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
5 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
6 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
7 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
FGFR2 2件: FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
8 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
FGFR2 2件: FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
9 | Gastric cancer 💬 20 genes, 29 drugs (DrugBank) and 57 diseases |
FGFR2 1件: FGFR2 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
10 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
11 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
12 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
13 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
14 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
FGFR3 1件: FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
15 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
16 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
17 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
18 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
19 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
GHR 1件: GHR 💬 |
D02691 D02691 💬 |
Somatotropin | 002 20件: 2 , 3 , 13, 19, 46, 74, 75, 76, 78, 96, 113, 187, 191, 193, 195, 236, 265, 274, 276, 299 💬 |
20 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
FGFR1 2件: FGFR1, FGFR2 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
21 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
22 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
23 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
24 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
25 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
FGFR1 3件: FGFR1, FGFR2, FGFR3 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |
26 | Thermogenesis 💬 17 genes, 27 drugs (DrugBank) and 74 diseases |
FGFR1 1件: FGFR1 💬 |
D11589 D11589 💬 |
Infigratinib | 276 1件: 276 💬 |