Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
2 | Adrenergic signaling in cardiomyocytes 💬 26 genes, 77 drugs (DrugBank) and 68 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
3 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
4 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A 1件: ADRA1A 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
5 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
ADRA1A 1件: ADRA1A 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
6 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
7 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
8 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
9 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
10 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
11 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
12 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
13 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
F10 2件: F10, F9 💬 |
D10821 D10821 💬 |
Emicizumab | 288 1件: 288 💬 |
14 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
F8 1件: F8 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
15 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
F8 1件: F8 💬 |
D02235 D02235 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
16 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 5件: 46, 70, 215, 227, 288 💬 |
17 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
SERPINC1 2件: SERPINC1, SERPIND1 💬 |
D08547 D08547 💬 |
Sulodexide | 013 5件: 13, 51, 223, 271, 288 💬 |
18 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL11RA 1件: IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 2件: 96, 288 💬 |
19 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL11RA 1件: IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 2件: 96, 288 💬 |
20 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
MS4A1 1件: MS4A1 💬 |
D02994 D02994 💬 |
Rituximab | 011 47件: 11, 13, 14, 17, 19, 35, 36, 41, 42, 43, 44, 45, 46, 49, 50, 51, 52, 53, 55, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 229, 256, 271, 274, 283, 284, 285, 288, 296, 300, 331 💬 |
21 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
22 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 5件: 46, 70, 215, 227, 288 💬 |
23 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL11RA 1件: IL11RA 💬 |
D05266 D05266 💬 |
Oprelvekin | 096 2件: 96, 288 💬 |
24 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
25 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
26 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
ADRA1A 6件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
27 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
28 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
AVPR2 1件: AVPR2 💬 |
D02235 D02235 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
29 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 47件: 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
30 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 5件: 46, 70, 215, 227, 288 💬 |
31 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
32 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
33 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
34 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
AVPR2 1件: AVPR2 💬 |
D02235 D02235 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
35 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
36 | Proteasome 💬 2 genes, 5 drugs (DrugBank) and 17 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
37 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
38 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
39 | Spinocerebellar ataxia 💬 16 genes, 23 drugs (DrugBank) and 66 diseases |
PSMB5 1件: PSMB5 💬 |
D03150 D03150 💬 |
Bortezomib | 011 15件: 11, 13, 26, 28, 46, 49, 51, 61, 63, 66, 228, 256, 283, 288, 331 💬 |
40 | Staphylococcus aureus infection 💬 24 genes, 15 drugs (DrugBank) and 32 diseases |
PLG 1件: PLG 💬 |
D01136 D01136 💬 |
Tranexamic acid | 046 5件: 46, 70, 215, 227, 288 💬 |
41 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D00434 D00434 💬 |
Simvastatin | 006 21件: 6 , 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 160, 162, 195, 265, 288, 298, 299, 310 💬 |
42 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D00680 D00680 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
43 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
ADRA1A 3件: ADRA1A, ADRA1B, ADRA1D 💬 |
D08207 D08207 💬 |
Methylergometrine | 118 2件: 118, 288 💬 |
44 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 9 diseases |
AVPR2 1件: AVPR2 💬 |
D00291 D00291 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |
45 | Vasopressin-regulated water reabsorption 💬 1 gene, 5 drugs (DrugBank) and 9 diseases |
AVPR2 1件: AVPR2 💬 |
D02235 D02235 💬 |
Desmopressin | 006 6件: 6 , 64, 72, 75, 225, 288 💬 |