Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
2 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
3 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
4 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
5 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
6 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
7 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
8 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
9 | Apoptosis - multiple species 💬 3 genes, 3 drugs (DrugBank) and 8 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
10 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
11 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
12 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
13 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
14 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
15 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
16 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
17 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
18 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
19 | Colorectal cancer 💬 14 genes, 19 drugs (DrugBank) and 49 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
20 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
21 | DNA replication 💬 2 genes, 1 drug (DrugBank) and 9 diseases |
POLA1 2件: POLA1, POLA2 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
22 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
23 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
24 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
25 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
26 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
PTH1R 1件: PTH1R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 4件: 65, 70, 235, 326 💬 |
27 | Endocrine and other factor-regulated calcium reabsorption 💬 7 genes, 25 drugs (DrugBank) and 49 diseases |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 8件: 37, 46, 49, 66, 96, 158, 235, 326 💬 |
28 | Endometrial cancer 💬 10 genes, 14 drugs (DrugBank) and 21 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
29 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
30 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
31 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
32 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
33 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
34 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
35 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
36 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
37 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
38 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
39 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
40 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
41 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
42 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
43 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
44 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
45 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
46 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
47 | Huntington disease 💬 23 genes, 29 drugs (DrugBank) and 77 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
48 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
49 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
50 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
51 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
52 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
53 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
IFNGR1 1件: IFNGR1 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
54 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
55 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
56 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
57 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
58 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
59 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
60 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
61 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
62 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
63 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
64 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
65 | Mineral absorption 💬 8 genes, 13 drugs (DrugBank) and 37 diseases |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 8件: 37, 46, 49, 66, 96, 158, 235, 326 💬 |
66 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
67 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
68 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
69 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTH1R 2件: PTH1R, PTH2R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 4件: 65, 70, 235, 326 💬 |
70 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
71 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
72 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
73 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
74 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
75 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
76 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
77 | p53 signaling pathway 💬 3 genes, 3 drugs (DrugBank) and 12 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
78 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
79 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
PTH1R 1件: PTH1R 💬 |
D05364 D05364 💬 |
Parathyroid hormone | 065 4件: 65, 70, 235, 326 💬 |
80 | Parathyroid hormone synthesis, secretion and action 💬 19 genes, 40 drugs (DrugBank) and 58 diseases |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 8件: 37, 46, 49, 66, 96, 158, 235, 326 💬 |
81 | Parkinson disease 💬 21 genes, 64 drugs (DrugBank) and 63 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
82 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
83 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
84 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
85 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
86 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
87 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
88 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
89 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
90 | Platinum drug resistance 💬 9 genes, 12 drugs (DrugBank) and 22 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
91 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
92 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
93 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
94 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
95 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
96 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
97 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
98 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 1件: RRM1 💬 |
D01907 D01907 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
99 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 1件: RRM1 💬 |
D07966 D07966 💬 |
Fludarabine | 013 18件: 13, 19, 28, 36, 46, 49, 51, 60, 61, 62, 65, 85, 96, 164, 283, 284, 285, 326 💬 |
100 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
101 | Small cell lung cancer 💬 11 genes, 35 drugs (DrugBank) and 51 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
102 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
103 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
104 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
105 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
106 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
107 | Thyroid hormone signaling pathway 💬 22 genes, 35 drugs (DrugBank) and 61 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
108 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
109 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
110 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
111 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
IFNGR1 2件: IFNGR1, IFNGR2 💬 |
D00747 D00747 💬 |
Interferon gamma-1b | 018 7件: 18, 65, 85, 228, 299, 301, 326 💬 |
112 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
113 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
VDR 1件: VDR 💬 |
D00129 D00129 💬 |
Calcitriol | 037 8件: 37, 46, 49, 66, 96, 158, 235, 326 💬 |
114 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
115 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
116 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
CASP9 1件: CASP9 💬 |
D11195 D11195 💬 |
Rimiducid | 019 6件: 19, 60, 65, 284, 285, 326 💬 |
117 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |