Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
2 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
3 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
4 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
5 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
6 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
7 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
8 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
9 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
10 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
11 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
12 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
13 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
14 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
15 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
16 | Amphetamine addiction 💬 24 genes, 48 drugs (DrugBank) and 87 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
17 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
18 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
19 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
20 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
21 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
22 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
23 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
24 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
25 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
26 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
27 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
28 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
29 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
30 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
31 | B cell receptor signaling pathway 💬 16 genes, 19 drugs (DrugBank) and 63 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
32 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
33 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
34 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
DHODH 1件: DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 💬 |
35 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
36 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
37 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
38 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
39 | Cellular senescence 💬 29 genes, 35 drugs (DrugBank) and 90 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
40 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
OPRD1 1件: OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
41 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
OPRD1 1件: OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
42 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
43 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
44 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
45 | Chemokine signaling pathway 💬 20 genes, 23 drugs (DrugBank) and 41 diseases |
JAK2 2件: JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
46 | Cholinergic synapse 💬 31 genes, 48 drugs (DrugBank) and 58 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
47 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
48 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
49 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
50 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
51 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
52 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
53 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
54 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
55 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
56 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
57 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
58 | DNA replication 💬 2 genes, 1 drug (DrugBank) and 9 diseases |
POLA1 2件: POLA1, POLA2 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
59 | Dopaminergic synapse 💬 30 genes, 93 drugs (DrugBank) and 97 diseases |
PPP3CA 3件: PPP3CA, PPP3CB, PPP3CC 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
60 | Drug metabolism - other enzymes 💬 8 genes, 13 drugs (DrugBank) and 46 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
61 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
62 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
63 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
64 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
65 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
66 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
67 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
68 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 1件: OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
69 | Estrogen signaling pathway 💬 19 genes, 66 drugs (DrugBank) and 61 diseases |
OPRM1 1件: OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
70 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
71 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
72 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
73 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
74 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
75 | Folate biosynthesis 💬 6 genes, 4 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
76 | Glucagon signaling pathway 💬 13 genes, 18 drugs (DrugBank) and 78 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
77 | Glutamatergic synapse 💬 22 genes, 26 drugs (DrugBank) and 79 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
78 | Glutathione metabolism 💬 4 genes, 6 drugs (DrugBank) and 24 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
79 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
80 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
81 | Growth hormone synthesis, secretion and action 💬 23 genes, 38 drugs (DrugBank) and 81 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
82 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
83 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
84 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
85 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
86 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
87 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
88 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
89 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
90 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
91 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
92 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
93 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
94 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
95 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
96 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
97 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
98 | HIF-1 signaling pathway 💬 20 genes, 40 drugs (DrugBank) and 73 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
99 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
100 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 1件: JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
101 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
102 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
103 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
104 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
105 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
106 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
107 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
108 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
109 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
110 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
111 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
112 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
113 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
JAK1 2件: JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
114 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
115 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
116 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
117 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
118 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
119 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
120 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
121 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
122 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
123 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
124 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
125 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
126 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
127 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
128 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
129 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
130 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
131 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
132 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
133 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
134 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
135 | Kaposi sarcoma-associated herpesvirus infection 💬 52 genes, 75 drugs (DrugBank) and 105 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
136 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
137 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
138 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
139 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
140 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
141 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
142 | Long-term potentiation 💬 17 genes, 30 drugs (DrugBank) and 82 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
143 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
144 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
145 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
146 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
147 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
148 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
149 | Measles 💬 36 genes, 37 drugs (DrugBank) and 49 diseases |
JAK1 3件: JAK1, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
150 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
151 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
152 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
DHODH 1件: DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 💬 |
153 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
154 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 1件: OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
155 | Morphine addiction 💬 40 genes, 59 drugs (DrugBank) and 71 diseases |
OPRM1 1件: OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
156 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
157 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
158 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
159 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
160 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
161 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
162 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
163 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
164 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
165 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00407 D00407 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
166 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00751 D00751 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
167 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00979 D00979 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
168 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05000 D05000 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
169 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05001 D05001 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
170 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D05002 D05002 💬 |
Methylprednisolone | 002 44件: 2 , 6 , 11, 13, 14, 18, 19, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 127, 145, 162, 164, 211, 220, 222, 224, 271, 283, 284, 285, 296 💬 |
171 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00472 D00472 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
172 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00980 D00980 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
173 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00981 D00981 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
174 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00982 D00982 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
175 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D01239 D01239 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
176 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D01998 D01998 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
177 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D02156 D02156 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
178 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D03301 D03301 💬 |
Prednisolone | 011 40件: 11, 13, 14, 25, 26, 35, 38, 39, 40, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 💬 |
179 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D00473 D00473 💬 |
Prednisone | 002 47件: 2 , 6 , 11, 13, 14, 19, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 93, 95, 96, 97, 113, 127, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 💬 |
180 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
NR3C1 1件: NR3C1 💬 |
D08416 D08416 💬 |
Prednisone acetate | 035 6件: 35, 40, 41, 49, 162, 224 💬 |
181 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRD1 3件: OPRD1, OPRK1, OPRM1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
182 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
OPRD1 3件: OPRD1, OPRK1, OPRM1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
183 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
184 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
185 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
186 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
187 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
188 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
189 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
190 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
191 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
192 | Non-small cell lung cancer 💬 18 genes, 27 drugs (DrugBank) and 42 diseases |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
193 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D00142 D00142 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
194 | One carbon pool by folate 💬 3 genes, 3 drugs (DrugBank) and 36 diseases |
DHFR 2件: DHFR, DHFR2 💬 |
D02115 D02115 💬 |
Methotrexate | 011 35件: 11, 13, 19, 34, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 107, 162, 164, 172, 256, 271, 284, 285, 326, 331 💬 |
195 | Oocyte meiosis 💬 14 genes, 38 drugs (DrugBank) and 75 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
196 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
197 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
198 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
199 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
200 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
201 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
202 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
203 | Pancreatic cancer 💬 16 genes, 29 drugs (DrugBank) and 64 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
204 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
205 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
206 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
207 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
208 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
209 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
210 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
211 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
212 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
213 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
214 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
215 | PD-L1 expression and PD-1 checkpoint pathway in cancer 💬 31 genes, 42 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
216 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
217 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
218 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
219 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
220 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
221 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
222 | Primary immunodeficiency 💬 10 genes, 17 drugs (DrugBank) and 22 diseases |
JAK3 1件: JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
223 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
224 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
225 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
226 | Prolactin signaling pathway 💬 18 genes, 33 drugs (DrugBank) and 48 diseases |
JAK2 1件: JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
227 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
228 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
229 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
230 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
DHODH 1件: DHODH 💬 |
D00749 D00749 💬 |
Leflunomide | 011 10件: 11, 40, 46, 49, 53, 66, 162, 224, 271, 300 💬 |
231 | Pyrimidine metabolism 💬 4 genes, 8 drugs (DrugBank) and 32 diseases |
RRM1 1件: RRM1 💬 |
D03546 D03546 💬 |
Clofarabine | 019 9件: 19, 20, 40, 46, 49, 60, 96, 234, 326 💬 |
232 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
233 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
234 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
235 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
236 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
237 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
238 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
239 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
240 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
241 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
242 | Signaling pathways regulating pluripotency of stem cells 💬 20 genes, 24 drugs (DrugBank) and 43 diseases |
JAK1 3件: JAK1, JAK2, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
243 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
OPRD1 1件: OPRD1 💬 |
D02095 D02095 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
244 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
OPRD1 1件: OPRD1 💬 |
D05113 D05113 💬 |
Naltrexone | 006 13件: 6 , 10, 13, 40, 41, 42, 43, 44, 45, 46, 96, 97, 226 💬 |
245 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
246 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
247 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
248 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
249 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
250 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
251 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
252 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
253 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
254 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
255 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
256 | Th1 and Th2 cell differentiation 💬 44 genes, 33 drugs (DrugBank) and 69 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
257 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
258 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
259 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
JAK1 4件: JAK1, JAK2, JAK3, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
260 | Th17 cell differentiation 💬 53 genes, 60 drugs (DrugBank) and 96 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
261 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
262 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
263 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
264 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
265 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
266 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
JAK1 3件: JAK1, JAK2, TYK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
267 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
268 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
269 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
270 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
JAK1 2件: JAK1, JAK2 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
271 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
272 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
273 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
274 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
275 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
276 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
277 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
278 | VEGF signaling pathway 💬 20 genes, 48 drugs (DrugBank) and 84 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
279 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 1件: JAK1 💬 |
D10994 D10994 💬 |
Upadacitinib | 040 7件: 40, 41, 46, 49, 96, 97, 271 💬 |
280 | Viral carcinogenesis 💬 27 genes, 19 drugs (DrugBank) and 36 diseases |
JAK1 2件: JAK1, JAK3 💬 |
D09970 D09970 💬 |
Tofacitinib | 011 12件: 11, 40, 46, 49, 50, 51, 53, 84, 96, 97, 107, 271 💬 |
281 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
IL6R 1件: IL6R 💬 |
D02596 D02596 💬 |
Tocilizumab | 002 18件: 2 , 13, 40, 41, 42, 43, 46, 50, 51, 53, 54, 55, 56, 86, 107, 266, 271, 331 💬 |
282 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
283 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |
284 | Wnt signaling pathway 💬 8 genes, 7 drugs (DrugBank) and 56 diseases |
PPP3CA 5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 💬 |
D00184 D00184 💬 |
Cyclosporine | 011 43件: 11, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 93, 95, 97, 113, 162, 164, 222, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 💬 |
285 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
286 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02598 D02598 💬 |
Infliximab | 035 25件: 35, 37, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 55, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 💬 |