Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
2 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
3 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
4 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
5 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
6 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
7 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
8 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
EPOR 1件: EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 10件: 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
9 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
10 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
EPOR 1件: EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 10件: 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
11 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
12 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
EPOR 1件: EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 10件: 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
13 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
14 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
15 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
16 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
17 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
18 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
19 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
20 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EPOR 1件: EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 10件: 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
21 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
CSF3R 1件: CSF3R 💬 |
D03235 D03235 💬 |
Filgrastim | 002 33件: 2 , 6 , 11, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 47, 49, 51, 57, 60, 62, 65, 85, 96, 113, 164, 256, 283, 284, 285, 296, 331 💬 |
22 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
EPOR 1件: EPOR 💬 |
D03231 D03231 💬 |
Erythropoietin | 002 10件: 2 , 6 , 13, 18, 22, 46, 47, 70, 95, 96 💬 |
23 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
24 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
25 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
26 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
27 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
28 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |