Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT 1件: KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
2 | Acute myeloid leukemia 💬 15 genes, 25 drugs (DrugBank) and 59 diseases |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
3 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
4 | AMPK signaling pathway 💬 16 genes, 47 drugs (DrugBank) and 86 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
5 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
6 | Axon guidance 💬 21 genes, 19 drugs (DrugBank) and 65 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
7 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
8 | Bile secretion 💬 11 genes, 29 drugs (DrugBank) and 58 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
9 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
10 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
11 | Biosynthesis of cofactors 💬 10 genes, 10 drugs (DrugBank) and 45 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
12 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT 1件: KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
13 | Breast cancer 💬 18 genes, 51 drugs (DrugBank) and 69 diseases |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
14 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
15 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
16 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
17 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
18 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
19 | Calcium signaling pathway 💬 74 genes, 175 drugs (DrugBank) and 126 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
20 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
21 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
22 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
23 | cAMP signaling pathway 💬 63 genes, 157 drugs (DrugBank) and 108 diseases |
EDNRA 1件: EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
24 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
25 | Cell cycle 💬 7 genes, 8 drugs (DrugBank) and 23 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
26 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
27 | Central carbon metabolism in cancer 💬 18 genes, 24 drugs (DrugBank) and 55 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
28 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
29 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
30 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
31 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
32 | cGMP-PKG signaling pathway 💬 45 genes, 108 drugs (DrugBank) and 112 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
33 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
34 | Choline metabolism in cancer 💬 10 genes, 20 drugs (DrugBank) and 51 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
35 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
36 | Chronic myeloid leukemia 💬 14 genes, 15 drugs (DrugBank) and 28 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
37 | Circadian entrainment 💬 21 genes, 30 drugs (DrugBank) and 54 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
38 | Complement and coagulation cascades 💬 15 genes, 24 drugs (DrugBank) and 42 diseases |
F10 1件: F10 💬 |
D09710 D09710 💬 |
Edoxaban | 046 2件: 46, 88 💬 |
39 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
40 | EGFR tyrosine kinase inhibitor resistance 💬 25 genes, 49 drugs (DrugBank) and 81 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
41 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
42 | Endocytosis 💬 20 genes, 27 drugs (DrugBank) and 50 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
43 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
44 | ErbB signaling pathway 💬 12 genes, 21 drugs (DrugBank) and 51 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
45 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
46 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
47 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
48 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
49 | Focal adhesion 💬 26 genes, 37 drugs (DrugBank) and 42 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
50 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
51 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
52 | Gap junction 💬 25 genes, 76 drugs (DrugBank) and 72 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
53 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
54 | Glioma 💬 12 genes, 24 drugs (DrugBank) and 56 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
55 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT 1件: KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
56 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
57 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
58 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
59 | Hepatocellular carcinoma 💬 18 genes, 25 drugs (DrugBank) and 57 diseases |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
60 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
61 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
62 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
63 | JAK-STAT signaling pathway 💬 54 genes, 83 drugs (DrugBank) and 104 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
64 | Long-term depression 💬 12 genes, 15 drugs (DrugBank) and 29 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
65 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
66 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
67 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
68 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
69 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
EDNRB 1件: EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
70 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT 1件: KIT 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
71 | Melanogenesis 💬 5 genes, 11 drugs (DrugBank) and 25 diseases |
KIT 1件: KIT 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
72 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
73 | Melanoma 💬 13 genes, 23 drugs (DrugBank) and 34 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
74 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
75 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
76 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
77 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
78 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
79 | Metabolic pathways 💬 104 genes, 142 drugs (DrugBank) and 128 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
80 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ABL1 2件: ABL1, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
81 | MicroRNAs in cancer 💬 30 genes, 59 drugs (DrugBank) and 77 diseases |
ABL1 2件: ABL1, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
82 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
83 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
84 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
85 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
86 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR 1件: PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 5件: 51, 70, 84, 86, 88 💬 |
87 | Neuroactive ligand-receptor interaction 💬 146 genes, 309 drugs (DrugBank) and 144 diseases |
PTGIR 1件: PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 |
88 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
89 | Neurotrophin signaling pathway 💬 19 genes, 21 drugs (DrugBank) and 29 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
90 | Oxytocin signaling pathway 💬 33 genes, 65 drugs (DrugBank) and 99 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
91 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
92 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
93 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ABL1 3件: ABL1, KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
94 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
ABL1 3件: ABL1, KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
95 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
96 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
97 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
98 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
EDNRA 2件: EDNRA, EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
99 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
NQO1 1件: NQO1 💬 |
D00564 D00564 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
100 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
NQO1 1件: NQO1 💬 |
D01280 D01280 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
101 | Pathways in cancer 💬 97 genes, 177 drugs (DrugBank) and 130 diseases |
NQO1 1件: NQO1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
102 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
103 | Phospholipase D signaling pathway 💬 23 genes, 45 drugs (DrugBank) and 75 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
104 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
105 | PI3K-Akt signaling pathway 💬 70 genes, 106 drugs (DrugBank) and 116 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
106 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
107 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR 1件: PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 5件: 51, 70, 84, 86, 88 💬 |
108 | Platelet activation 💬 22 genes, 44 drugs (DrugBank) and 47 diseases |
PTGIR 1件: PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 |
109 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
110 | Prostate cancer 💬 21 genes, 46 drugs (DrugBank) and 78 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
111 | Purine metabolism 💬 30 genes, 31 drugs (DrugBank) and 68 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
112 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
113 | Rap1 signaling pathway 💬 40 genes, 91 drugs (DrugBank) and 82 diseases |
KIT 2件: KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
114 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
ABL1 3件: ABL1, KIT, PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
115 | Ras signaling pathway 💬 32 genes, 45 drugs (DrugBank) and 58 diseases |
ABL1 3件: ABL1, KIT, PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
116 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
PDGFRA 1件: PDGFRA 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
117 | Regulation of actin cytoskeleton 💬 26 genes, 50 drugs (DrugBank) and 53 diseases |
PDGFRA 1件: PDGFRA 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
118 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
119 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
120 | Relaxin signaling pathway 💬 18 genes, 25 drugs (DrugBank) and 38 diseases |
EDNRB 1件: EDNRB 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
121 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
122 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
123 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
124 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
EDNRA 1件: EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
125 | Renin secretion 💬 28 genes, 77 drugs (DrugBank) and 105 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
126 | Salivary secretion 💬 16 genes, 58 drugs (DrugBank) and 55 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
127 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D00887 D00887 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
128 | Terpenoid backbone biosynthesis 💬 4 genes, 13 drugs (DrugBank) and 48 diseases |
HMGCR 1件: HMGCR 💬 |
D07474 D07474 💬 |
Atorvastatin | 013 17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 💬 |
129 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D00564 D00564 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
130 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D01280 D01280 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
131 | Ubiquinone and other terpenoid-quinone biosynthesis 💬 3 genes, 3 drugs (DrugBank) and 14 diseases |
NQO1 2件: NQO1, VKORC1 💬 |
D08682 D08682 💬 |
Warfarin | 006 11件: 6 , 8 , 13, 19, 46, 49, 66, 85, 88, 96, 97 💬 |
132 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D07077 D07077 💬 |
Ambrisentan | 051 7件: 51, 84, 85, 86, 88, 210, 211 💬 |
133 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D01227 D01227 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
134 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D07538 D07538 💬 |
Bosentan | 013 11件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211, 212 💬 |
135 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
EDNRA 1件: EDNRA 💬 |
D10135 D10135 💬 |
Macitentan | 051 5件: 51, 85, 86, 88, 210 💬 |
136 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
GUCY1A1 3件: GUCY1A1, GUCY1A2, GUCY1B1 💬 |
D09572 D09572 💬 |
Riociguat | 051 6件: 51, 84, 86, 88, 225, 299 💬 |
137 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR 1件: PTGIR 💬 |
D09994 D09994 💬 |
Selexipag | 051 5件: 51, 70, 84, 86, 88 💬 |
138 | Vascular smooth muscle contraction 💬 30 genes, 71 drugs (DrugBank) and 65 diseases |
PTGIR 1件: PTGIR 💬 |
D06213 D06213 💬 |
Treprostinil | 051 6件: 51, 84, 85, 86, 88, 210 💬 |
139 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ABL1 1件: ABL1 💬 |
D01441 D01441 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |
140 | Viral myocarditis 💬 29 genes, 18 drugs (DrugBank) and 46 diseases |
ABL1 1件: ABL1 💬 |
D08066 D08066 💬 |
Imatinib | 013 12件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 88, 89, 162 💬 |