Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)💬 Info on mouse-over
No. | KEGG PATHWAY On map, Yellow: Drug target, Red: All disease-related |
KEGG GENES | KEGG DRUG | DrugBank | 指定難病告示番号 |
1 | Adipocytokine signaling pathway 💬 15 genes, 30 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
2 | African trypanosomiasis 💬 7 genes, 19 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
3 | AGE-RAGE signaling pathway in diabetic complications 💬 23 genes, 40 drugs (DrugBank) and 84 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
4 | Allograft rejection 💬 30 genes, 22 drugs (DrugBank) and 57 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
5 | Alzheimer disease 💬 54 genes, 110 drugs (DrugBank) and 116 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
6 | Amoebiasis 💬 17 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
7 | Amyotrophic lateral sclerosis 💬 33 genes, 44 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
8 | Antifolate resistance 💬 7 genes, 20 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
9 | Antigen processing and presentation 💬 23 genes, 15 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
10 | Apoptosis 💬 14 genes, 23 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
11 | Asthma 💬 21 genes, 21 drugs (DrugBank) and 55 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
12 | C-type lectin receptor signaling pathway 💬 25 genes, 60 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
13 | Chagas disease 💬 25 genes, 39 drugs (DrugBank) and 76 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
14 | Coronavirus disease - COVID-19 💬 47 genes, 82 drugs (DrugBank) and 93 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
15 | Cytokine-cytokine receptor interaction 💬 74 genes, 100 drugs (DrugBank) and 97 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
16 | Dilated cardiomyopathy 💬 16 genes, 52 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
17 | Epstein-Barr virus infection 💬 61 genes, 52 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
18 | Fc epsilon RI signaling pathway 💬 19 genes, 35 drugs (DrugBank) and 59 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
19 | Fluid shear stress and atherosclerosis 💬 29 genes, 46 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
20 | Graft-versus-host disease 💬 27 genes, 22 drugs (DrugBank) and 61 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
21 | Hematopoietic cell lineage 💬 43 genes, 65 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
22 | Hepatitis B 💬 39 genes, 46 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
23 | Hepatitis C 💬 31 genes, 51 drugs (DrugBank) and 70 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
24 | Herpes simplex virus 1 infection 💬 60 genes, 56 drugs (DrugBank) and 95 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
25 | Human cytomegalovirus infection 💬 58 genes, 94 drugs (DrugBank) and 113 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
26 | Human immunodeficiency virus 1 infection 💬 44 genes, 38 drugs (DrugBank) and 85 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
27 | Human papillomavirus infection 💬 43 genes, 83 drugs (DrugBank) and 102 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
28 | Human T-cell leukemia virus 1 infection 💬 52 genes, 50 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
29 | Hypertrophic cardiomyopathy 💬 19 genes, 49 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
30 | IL-17 signaling pathway 💬 18 genes, 56 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
31 | Inflammatory bowel disease 💬 35 genes, 40 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
32 | Influenza A 💬 54 genes, 55 drugs (DrugBank) and 81 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
33 | Insulin resistance 💬 16 genes, 29 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
34 | Legionellosis 💬 7 genes, 19 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
35 | Leishmaniasis 💬 35 genes, 58 drugs (DrugBank) and 88 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
36 | Malaria 💬 14 genes, 25 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
37 | MAPK signaling pathway 💬 57 genes, 76 drugs (DrugBank) and 106 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
38 | mTOR signaling pathway 💬 13 genes, 28 drugs (DrugBank) and 86 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
39 | Natural killer cell mediated cytotoxicity 💬 41 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
40 | Necroptosis 💬 28 genes, 37 drugs (DrugBank) and 68 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
41 | NF-kappa B signaling pathway 💬 17 genes, 59 drugs (DrugBank) and 82 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
42 | NOD-like receptor signaling pathway 💬 29 genes, 38 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
43 | Non-alcoholic fatty liver disease 💬 17 genes, 37 drugs (DrugBank) and 80 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
44 | Osteoclast differentiation 💬 34 genes, 58 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
45 | Pathogenic Escherichia coli infection 💬 25 genes, 35 drugs (DrugBank) and 71 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
46 | Pathways of neurodegeneration - multiple diseases 💬 56 genes, 111 drugs (DrugBank) and 117 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
47 | Pertussis 💬 16 genes, 32 drugs (DrugBank) and 65 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
48 | Prion disease 💬 40 genes, 59 drugs (DrugBank) and 103 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
49 | Proteoglycans in cancer 💬 28 genes, 60 drugs (DrugBank) and 92 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
50 | Rheumatoid arthritis 💬 37 genes, 49 drugs (DrugBank) and 73 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
51 | RIG-I-like receptor signaling pathway 💬 21 genes, 17 drugs (DrugBank) and 53 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
52 | Salmonella infection 💬 25 genes, 32 drugs (DrugBank) and 62 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
53 | Shigellosis 💬 21 genes, 36 drugs (DrugBank) and 83 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
54 | Sphingolipid signaling pathway 💬 28 genes, 45 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
55 | Systemic lupus erythematosus 💬 27 genes, 34 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
56 | T cell receptor signaling pathway 💬 30 genes, 39 drugs (DrugBank) and 77 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
57 | TGF-beta signaling pathway 💬 11 genes, 20 drugs (DrugBank) and 54 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
58 | TNF signaling pathway 💬 18 genes, 51 drugs (DrugBank) and 79 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
59 | Toll-like receptor signaling pathway 💬 34 genes, 39 drugs (DrugBank) and 64 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
60 | Toxoplasmosis 💬 38 genes, 36 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
61 | Tuberculosis 💬 60 genes, 61 drugs (DrugBank) and 89 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
62 | Type I diabetes mellitus 💬 31 genes, 23 drugs (DrugBank) and 69 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
63 | Type II diabetes mellitus 💬 14 genes, 38 drugs (DrugBank) and 90 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
64 | Viral protein interaction with cytokine and cytokine receptor 💬 17 genes, 27 drugs (DrugBank) and 58 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |
65 | Yersinia infection 💬 20 genes, 32 drugs (DrugBank) and 66 diseases |
TNF 1件: TNF 💬 |
D02597 D02597 💬 |
Adalimumab | 019 16件: 19, 37, 40, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 💬 |