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e.g. Sirolimus, Adalimumab

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97 / 17,542 descriptions

No. Drug (Description in trials) DrugBank KEGG DRUG KEGG GENES KEGG PATHWAY
On map, Yellow: Drug target genes		 Disease ID
 1  100 mg elx /50 mg tez /75 mg iva fdc  -  -  -  -  [1] 299 💬 
 2  100 mg elx/50 mg tez /75 mg iva fdc  -  -  -  -  [1] 299 💬 
 3  100 mg elx/50 mg tez/75 mg iva fixed dose combination  -  -  -  -  [1] 299 💬 
 4  100 mg vx-445/50 mg tez /75 mg iva fdc  -  -  -  -  [1] 299 💬 
 5  100-mg elx (vx-445) / 50-mg tez / 75-mg iva fdc  -  -  -  -  [1] 299 💬 
 6  100-mg elx (vx-455) / 50-mg tez / 75-mg iva fdc  -  -  -  -  [1] 299 💬 
 7  100-mg elx / 50-mg tez / 75 -mg iva fdc  -  -  -  -  [1] 299 💬 
 8  100-mg vx-445 / 50-mg tez / 75-mg iva fdc  -  -  -  -  [1] 299 💬 
 9  100-mg vx-445 /50-mg tez/75-mg  -  -  -  -  [1] 299 💬 
 10  100-mg vx-445/50-mg tez/75-mg iva fdc  -  -  -  -  [1] 299 💬 
 11  100mg vx-445/50mg tez /75mg iva fdc  -  -  -  -  [1] 299 💬 
 12  56/104/75-c  -  -  -  -  [1] 50 💬 
 13  75  -  -  -  -  [1]  6  💬 
 14  75 mg ontamalimab  Ontamalimab  -  -  -  [2] 96, 97 💬 
 15  750 mg metformin and 7.5 g l-citrulline daily p.o.  Citrulline  [3] D00944, D04966, D07706 💬  [2] PRKAA1, PRKAA2 💬  [19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway  [1] 113 💬 
 16  750mg mesalazine pellets  Mesalazine  [1] D00377 💬  -  -  [1] 97 💬 
 17  75mg cxa-10  CXA-10  -  -  -  [1] 86 💬 
 18  75mg shp647 (pf-00547659)  -  -  -  -  [1] 97 💬 
 19  Ain457, 75 mg  -  -  -  -  [1] 271 💬 
 20  Atacicept 75 mg  Atacicept  [1] D09704 💬  [2] TNFSF13, TNFSF13B 💬  [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis  [3] 13, 49, 66 💬 
 21  Atacicept 75 milligram (mg)  Atacicept  [1] D09704 💬  [2] TNFSF13, TNFSF13B 💬  [4] Cytokine-cytokine receptor interaction, Intestinal immune network for IgA production, NF-kappa B signaling pathway, Rheumatoid arthritis  [1] 49 💬 
 22  Azli 75 mg three times a day (tid)  -  -  -  -  [1] 299 💬 
 23  Azli 75 mg three times daily (tid)  -  -  -  -  [1] 299 💬 
 24  Azli 75 mg two times a day (bid)/ three times a day (tid)  -  -  -  -  [1] 299 💬 
 25  Azli 75 mg two times a day (bid)/three times a day (tid)  -  -  -  -  [1] 299 💬 
 26  Bms-986004 75 mg iv  -  -  -  -  [1] 63 💬 
 27  Bupivacaine  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [8] 46, 51, 53, 70, 96, 168, 226, 298 💬 
 28  Bupivacaine hydrochloride  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [2] 46, 53 💬 
 29  Bupivacaine hydrochloride 0.5% (marcaine, pfizer)  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 46 💬 
 30  Bupivacaine injection 0.5%  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 168 💬 
 31  Bupivacaine/epinephrine/dexamethasone  Bupivacaine  [14] D00095, D00292, D00975, D00996, D01450, D01510, D01615, D01632, D01948, D02149, D02174, D02591, D02592, D07552 💬  [15] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3, NR3C1, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 96 💬 
 32  Cayston 75 mg pulver und lösungsmittel zur herstellung einer lösung für einen vernebler  -  -  -  -  [1] 299 💬 
 33  Cayston aztreonam 75 mg powder and solvent for nebuliser solution  Aztreonam  [2] D00240, D06558 💬  -  -  [1] 299 💬 
 34  Certican 0,75mg  -  -  -  -  [1] 228 💬 
 35  Certican 0,75mg tabletten  -  -  -  -  [1] 228 💬 
 36  Cohort 2 0.75g  -  -  -  -  [1] 240 💬 
 37  Colistimethate 75 mg inhaled two times daily  Colistimethate  [1] D02049 💬  -  -  [1] 299 💬 
 38  Cvl-751  -  -  -  -  [1]  6  💬 
 39  Depot leuprolide acetate 3.75 mg  Acetate  [2] D00989, D08113 💬  [1] GNRHR 💬  [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction  [1] 51 💬 
 40  Efexor xl 75 mg  -  -  -  -  [1] 46 💬 
 41  Efexor xl 75 mg (venlafaxine)  Venlafaxine  [2] D00821, D08670 💬  [2] SLC6A2, SLC6A4 💬  [2] Serotonergic synapse, Synaptic vesicle cycle  [1] 46 💬 
 42  Ercp with bupivacaine infusion  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [1] 298 💬 
 43  Incobotulinumtoxina (75 units)  Botulinum toxin type A  [1] D00783 💬  [1] SNAP25 💬  [2] Insulin secretion, Synaptic vesicle cycle  [1]  6  💬 
 44  Inhaled nitric oxide 75 mcg/kg ibw/hr  Nitric Oxide  [1] D00074 💬  -  -  [2] 85, 86 💬 
 45  Ivacaftor 25 mg/75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 46  Ivacaftor 75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 47  Ivacaftor 75 mg/150 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 48  Jaktinib dihydrochloride monohydrate 50mg bid and mimic tablets of jakitinib hydrochloride 75mg bid and acetylcysteine effervescent tablets  Acetylcysteine  [1] D00221 💬  -  -  [1] 85 💬 
 49  Jaktinib dihydrochloride monohydrate 75mg bid and mimic tablets of jakitinib hydrochloride 50mg bid and acetylcysteine effervescent tablets  Acetylcysteine  [1] D00221 💬  -  -  [1] 85 💬 
 50  Jnj-54781532 75 mg once daily  -  -  -  -  [1] 97 💬 
 51  Jnj-54781532 75 mg twice daily  -  -  -  -  [1] 97 💬 
 52  Lap tap bupivacaine/epinephrine  Bupivacaine  [5] D00095, D00996, D01450, D02149, D07552 💬  [14] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 96 💬 
 53  Leuprorelin acetate 3.75mg injection  Acetate  [2] D00989, D08113 💬  [1] GNRHR 💬  [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction  [1] 76 💬 
 54  Levodopa 75 mg a cap  Levodopa  [1] D00059 💬  [5] DRD1, DRD2, DRD3, DRD4, DRD5 💬  [11] Alcoholism, Amphetamine addiction, Calcium signaling pathway, Cocaine addiction, Dopaminergic synapse, Gap junction, Morphine addiction, Neuroactive ligand-receptor interaction, Parkinson disease, Rap1 signaling pathway, cAMP signaling pathway  [1]  6  💬 
 55  Liposomal bupivacaine  Bupivacaine  [2] D01450, D07552 💬  [5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction  [3] 51, 70, 96 💬 
 56  Liq861 75 µg  -  -  -  -  [1] 86 💬 
 57  Luphere depot 3.75mg(leuprolide acetate 3.75mg)  Acetate  [2] D00989, D08113 💬  [1] GNRHR 💬  [2] GnRH signaling pathway, Neuroactive ligand-receptor interaction  [1] 76 💬 
 58  M2951 75 mg qd  -  -  -  -  [1] 46 💬 
 59  Macitentan 75 mg  Macitentan  [1] D10135 💬  [2] EDNRA, EDNRB 💬  [9] Calcium signaling pathway, Melanogenesis, Neuroactive ligand-receptor interaction, Pathways in cancer, Relaxin signaling pathway, Renin secretion, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 86 💬 
 60  Metohexal® succ ® 23,75 mg retardtabletten  -  -  -  -  [1] 113 💬 
 61  Oral glucose tolerance test (75g 2-hour)  Dextrose, unspecified form  -  -  -  [1] 299 💬 
 62  Other: glucose solution at a dose of 1.75 g/kg (up to a maximum of 75 g) for the ogtt and glucose solution at a dose of 0.5 g/kg (up to a maximum of 35 g) was injected in 2.5-3 min for the igtt  Dextrose, unspecified form  -  -  -  [1] 299 💬 
 63  Over-encapsulated 75 mg irbesartan tablets  Irbesartan  [1] D00523 💬  [1] AGTR1 💬  [16] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Coronavirus disease - COVID-19, Cortisol synthesis and secretion, Cushing syndrome, Diabetic cardiomyopathy, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway  [1] 222 💬 
 64  P2b001 once daily (pramipexole 0.3 mg / rasagiline 0.75 mg),  Pramipexole  [5] D00559, D02562, D05575, D08469, D10829 💬  [4] DRD2, DRD3, DRD4, MAOB 💬  [18] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway  [1]  6  💬 
 65  P2b001 once daily (pramipexole 0.6 mg / rasagiline 0.75 mg),  Pramipexole  [5] D00559, D02562, D05575, D08469, D10829 💬  [4] DRD2, DRD3, DRD4, MAOB 💬  [18] Alcoholism, Amphetamine addiction, Arginine and proline metabolism, Cocaine addiction, Dopaminergic synapse, Drug metabolism - cytochrome P450, Gap junction, Glycine, serine and threonine metabolism, Histidine metabolism, Metabolic pathways, Neuroactive ligand-receptor interaction, Parkinson disease, Phenylalanine metabolism, Rap1 signaling pathway, Serotonergic synapse, Tryptophan metabolism, Tyrosine metabolism, cAMP signaling pathway  [1]  6  💬 
 66  P38 inhibitor (4) 75mg  -  -  -  -  [1] 46 💬 
 67  Pregabalin 75mg  Pregabalin  [1] D02716 💬  [4] CACNA2D1, CACNA2D2, CACNA2D3, CACNA2D4 💬  [7] Adrenergic signaling in cardiomyocytes, Arrhythmogenic right ventricular cardiomyopathy, Cardiac muscle contraction, Dilated cardiomyopathy, Hypertrophic cardiomyopathy, MAPK signaling pathway, Oxytocin signaling pathway  [1] 70 💬 
 68  Ranexa*60cpr 750mg r.p.  -  -  -  -  [1] 58 💬 
 69  Ranolazine 750 mg pr tablets  Ranolazine  [2] D05700, D05701 💬  -  -  [1] 58 💬 
 70  Ranolazine pr (prolonged-release) 500 mg 1 tablet bis in die and 750 mg 1 tablet bis in die  Ranolazine  [2] D05700, D05701 💬  -  -  [1] 58 💬 
 71  Revolade 75 mg  -  -  -  -  [1] 60 💬 
 72  Rhudex 25 mg (31.75 mg rhudex choline salt) granules  Choline  [1] D07690 💬  -  -  [1] 93 💬 
 73  Ro 487-7533  -  -  -  -  [1] 46 💬 
 74  Ro 487-7533/f01  -  -  -  -  [2] 46, 271 💬 
 75  Ro 487-7533/f10  -  -  -  -  [1] 46 💬 
 76  Ro 487-7533/f10-02  -  -  -  -  [1] 46 💬 
 77  Ro 487-7533/f10-04  -  -  -  -  [4] 41, 46, 51, 107 💬 
 78  Ro 491-7523/f18  -  -  -  -  [1] 206 💬 
 79  Ro 491-7523/f19  -  -  -  -  [1] 206 💬 
 80  Ro487-7533  -  -  -  -  [1] 46 💬 
 81  Ro487-7533/f01-f05  -  -  -  -  [1] 46 💬 
 82  Ro487-7533/f10-04  -  -  -  -  [2] 46, 51 💬 
 83  Secukinumab (75 mg)  Secukinumab  [1] D09967 💬  [1] IL17A 💬  [5] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation  [1] 271 💬 
 84  Secukinumab 75 mg/0.5 ml solution for injection  Secukinumab  [1] D09967 💬  [1] IL17A 💬  [5] Cytokine-cytokine receptor interaction, IL-17 signaling pathway, Inflammatory bowel disease, Rheumatoid arthritis, Th17 cell differentiation  [1] 271 💬 
 85  Suspension containing 7500 embryonated viable trichuris suis ova/15ml  -  -  -  -  [1] 97 💬 
 86  Suspension containing 7500 embryonated, viable trichuris suis ova (tso)/15ml  -  -  -  -  [1] 96 💬 
 87  Suspension of 7500 embryonated, viable tso/15ml  -  -  -  -  [1] 96 💬 
 88  Tak-755 orbax930 or shp655  -  -  -  -  [1] 64 💬 
 89  Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere  -  -  -  -  [1] 13 💬 
 90  Trulicity 0,75 mg injekcný roztok naplnený v injekcnom pere.  -  -  -  -  [1] 13 💬 
 91  Tso 7500  -  -  -  -  [1] 96 💬 
 92  Us tap bupivacaine/epinephrine  Bupivacaine  [5] D00095, D00996, D01450, D02149, D07552 💬  [14] ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3, SCN1A, SCN2A, SCN3A, SCN5A, SCN9A 💬  [15] AMPK signaling pathway, Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy, Dopaminergic synapse, Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, Taste transduction, Thermogenesis, Vascular smooth muscle contraction, cAMP signaling pathway, cGMP-PKG signaling pathway  [1] 96 💬 
 93  Vamorolone 0.75 mg/day/day  Vamorolone  [1] D11000 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 113 💬 
 94  Vamorolone 0.75 mg/kg/day  Vamorolone  [1] D11000 💬  [1] NR3C1 💬  [1] Neuroactive ligand-receptor interaction  [1] 113 💬 
 95  Veltuzumab solution 75mg/ml  Veltuzumab  [1] D09031 💬  [1] MS4A1 💬  [1] Hematopoietic cell lineage  [1] 46 💬 
 96  Vx-661/ivacaftor 50 mg/ 75 mg  Ivacaftor  [1] D09916 💬  [1] CFTR 💬  [8] ABC transporters, AMPK signaling pathway, Bile secretion, Gastric acid secretion, Pancreatic secretion, Tight junction, Vibrio cholerae infection, cAMP signaling pathway  [1] 299 💬 
 97  Xyosted 75 milligram (mg) in 0.5 ml auto-injector  -  -  -  -  [1] 13 💬 

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