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No.	Drug (Description in trials)	DrugBank	KEGG DRUG	KEGG GENES	KEGG PATHWAY On map, Yellow: Drug target genes	Disease ID
1	[tachipirina cpr 500mg]	-	-	-	-	[1] 13 💬
2	Aricept 5*28 cpr 5 mg	-	-	-	-	[1] 124 💬
3	Clipper 30 cpr 5mg r.m.	-	-	-	-	[1] 97 💬
4	Comtan 200* 60 cpr 200 mg	-	-	-	-	[1]  6  💬
5	Cp	-	-	-	-	[6]  6 , 46, 96, 97, 107, 271 💬
6	Cp 690,550	-	-	-	-	[1] 46 💬
7	Cp 690550 mr	-	-	-	-	[1] 46 💬
8	Cp- 690 550	-	-	-	-	[1] 97 💬
9	Cp-195,543	-	-	-	-	[1] 46 💬
10	Cp-461	-	-	-	-	[1] 96 💬
11	Cp-690, 550 - 10	-	-	-	-	[1] 46 💬
12	Cp-690,500 5 mg	-	-	-	-	[1] 97 💬
13	Cp-690,55-10	-	-	-	-	[1] 46 💬
14	Cp-690,550	-	-	-	-	[4] 46, 96, 97, 271 💬
15	Cp-690,550 (tasocitinib)	Tofacitinib	[1] D09970 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis	[1] 46 💬
16	Cp-690,550 (tofacitinib)	Tofacitinib	[1] D09970 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis	[1] 46 💬
17	Cp-690,550 + methotrexate	Methotrexate	[2] D00142, D02115 💬	[2] DHFR, DHFR2 💬	[5] Antifolate resistance, Biosynthesis of cofactors, Folate biosynthesis, Metabolic pathways, One carbon pool by folate	[1] 46 💬
18	Cp-690,550 10 mg	-	-	-	-	[1] 97 💬
19	Cp-690,550 – 10	-	-	-	-	[1] 46 💬
20	Cp-690,550-10	-	-	-	-	[5] 46, 96, 97, 107, 271 💬
21	Cp-690-550	-	-	-	-	[1] 46 💬
22	Cp690,550	-	-	-	-	[2] 46, 97 💬
23	Cphc (carboxy pyrrolidine hexanoyl pyrrolidone carboxylate)	-	-	-	-	[1] 28 💬
24	Cpk850	-	-	-	-	[1] 90 💬
25	Cpp	-	-	-	-	[1] 76 💬
26	Cpsi-2364	-	-	-	-	[1] 96 💬
27	Cpx	-	-	-	-	[2] 215, 299 💬
28	Curcuma longa extract cpl formaat 00 23,2 x 8,5 mm 723 mg	Turmeric	-	-	-	[1] 299 💬
29	Deltacortene 10 cpr 25mg	-	-	-	-	[1] 97 💬
30	Deltacortene 20 cpr 5mg	-	-	-	-	[1] 97 💬
31	Eparmefolin 30 cpr 0,1/0,5mg	-	-	-	-	[1] 13 💬
32	Genisteine plus 150 mg cpl formaat 1 18,7 x 6,4 mm 438 mg	-	-	-	-	[1] 299 💬
33	Levofolene 4 mg 30 cpr	Levoleucovorin	[1] D04715 💬	-	-	[1] 13 💬
34	Metformin/cp-690,550	Metformin	[2] D00944, D04966 💬	[2] PRKAA1, PRKAA2 💬	[19] AMPK signaling pathway, Adipocytokine signaling pathway, Apelin signaling pathway, Autophagy - animal, Circadian rhythm, Fluid shear stress and atherosclerosis, FoxO signaling pathway, Glucagon signaling pathway, Hypertrophic cardiomyopathy, Insulin resistance, Insulin signaling pathway, Longevity regulating pathway, Longevity regulating pathway - multiple species, Non-alcoholic fatty liver disease, Oxytocin signaling pathway, PI3K-Akt signaling pathway, Thermogenesis, Tight junction, mTOR signaling pathway	[1] 46 💬
35	Nr2b nmda antagonist cp-101,606 (traxoprodil)	Ketamine	[2] D00711, D08098 💬	[5] GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D 💬	[20] Alcoholism, Alzheimer disease, Amphetamine addiction, Amyotrophic lateral sclerosis, Calcium signaling pathway, Circadian entrainment, Cocaine addiction, Dopaminergic synapse, Glutamatergic synapse, Huntington disease, Long-term potentiation, Neuroactive ligand-receptor interaction, Nicotine addiction, Pathways of neurodegeneration - multiple diseases, Prion disease, Rap1 signaling pathway, Ras signaling pathway, Spinocerebellar ataxia, Systemic lupus erythematosus, cAMP signaling pathway	[1]  6  💬
36	Other: comparator: cpet cycle ergometer (gold standard)	Gold	-	-	-	[1] 299 💬
37	Other: salbutamol nebulisation and with cpap	Salbutamol	[1] D02147 💬	[1] ADRB2 💬	[8] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway	[1] 228 💬
38	Other: transthoracic echocardiography at rest, during plr, hg and cpx (including blood gas analysis in both groups). additionally fallot patients will undergo routine blood testings.	-	-	-	-	[1] 215 💬
39	Requip 21 cpr 0,25 mg	-	-	-	-	[1]  6  💬
40	Requip 21 cpr 0,5 mg	-	-	-	-	[1]  6  💬
41	Requip 21 cpr 1 mg	-	-	-	-	[1]  6  💬
42	Requip 21 cpr 2 mg	-	-	-	-	[1]  6  💬
43	Reyataz 150mg 60 cps bl	-	-	-	-	[1] 265 💬
44	Tofacitinib (cp-690,550)	Tofacitinib	[1] D09970 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis	[1] 96 💬
45	Tofacitinib citrate cp-690550	Tofacitinib	[1] D09970 💬	[4] JAK1, JAK2, JAK3, TYK2 💬	[35] AGE-RAGE signaling pathway in diabetic complications, Adipocytokine signaling pathway, Chemokine signaling pathway, Cholinergic synapse, Coronavirus disease - COVID-19, EGFR tyrosine kinase inhibitor resistance, Epstein-Barr virus infection, Growth hormone synthesis, secretion and action, Hepatitis B, Hepatitis C, Herpes simplex virus 1 infection, Human T-cell leukemia virus 1 infection, Human cytomegalovirus infection, Human papillomavirus infection, Influenza A, JAK-STAT signaling pathway, Kaposi sarcoma-associated herpesvirus infection, Leishmaniasis, Measles, NOD-like receptor signaling pathway, Necroptosis, Non-small cell lung cancer, Osteoclast differentiation, PD-L1 expression and PD-1 checkpoint pathway in cancer, PI3K-Akt signaling pathway, Pancreatic cancer, Pathways in cancer, Primary immunodeficiency, Prolactin signaling pathway, Signaling pathways regulating pluripotency of stem cells, Th1 and Th2 cell differentiation, Th17 cell differentiation, Toxoplasmosis, Tuberculosis, Viral carcinogenesis	[1] 46 💬

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