3. Spinal muscular atrophy
179 clinical trials,   102 drugs   (DrugBank: 26 drugs),   52 drug target genes,   78 drug target pathways

Searched query = "Spinal muscular atrophy", "Myelopathic muscular atrophy", "SMA I", "Werdnig-Hoffman disease", "SMA II", "Dubowitz disease", "SMA III", "Kugelberg-Welander disease", "SMA IV"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

Search in Page e.g. "Phase 3", "Not recruiting", "Japan"
2 trials found
No.TrialIDDate_
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Public_titleScientific_titleConditionInterventionPrimary_
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agemin
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agemax
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PhaseCountries
1NCT00533221
(ClinicalTrials.gov)
October 200712/9/2007Pilot Study of Growth Hormon to Treat SMA Typ II and IIICan Treatment With Human Growth Hormone Increase Strength in Spinal Muscular Atrophy Type II and III?Muscular Atrophy, SpinalDrug: somatotropin;Drug: PlaceboUniversity Hospital FreiburgNovo Nordisk A/SCompleted6 Years35 YearsBoth20Phase 2Germany
2EUCTR2005-002822-78-DE
(EUCTR)
09/01/200621/11/2005Can treatment with human growth hormone increase strength in spinal muscular atrophy type II and III? - SMA-GHCan treatment with human growth hormone increase strength in spinal muscular atrophy type II and III? - SMA-GH Spinal muscular atrophy (SMA) is an autosomal recessive disease. Due to the genetic defect, a molecule called spinal motor neuron” (SMN) protein is lacking, resulting in muscle weakness. In SMAs muscle weakness is found most often at the level of proximal muscles. The disease is life-threatening and chronically debilitating.Trade Name: Norditropin SimpleXx
Product Name: Norditropin SimpleXx 15 mg/1.5 ml
Product Code: GH
INN or Proposed INN: Somatropin
Other descriptive name: Norditropin SimpleXx
Klinik Neuropädiatrie und MuskelkrankheitenNULLNot RecruitingFemale: yes
Male: yes
20Germany