DDrare: Database of Drug Development for Rare Diseases

Daraprim (DrugBank: -)

2 diseases

ID	Disease name (Link within this page)	Number of trials
2	Amyotrophic lateral sclerosis	1
4	Primary lateral sclerosis	1

2. Amyotrophic lateral sclerosis [ 508 clinical trials, 530 drugs, (DrugBank: 146 drugs), 170 drug target genes, 221 drug target pathways]

Searched query = "Amyotrophic lateral sclerosis", "ALS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 508 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-004798-99-DE (EUCTR)	27/02/2013	27/12/2012	Safety and Efficacy of SOD1 Inhibition By Pyrimethamine in Familial (ALS)	Safety and Efficacy of SOD1 Inhibition By Pyrimethamine in Familial (ALS) - Pyrimethamine In Familial ALS	Familial amyotrophic lateral sclerosis (FALS) MedDRA version: 14.1;Level: LLT;Classification code 10036704;Term: Primary lateral sclerosis;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Daraprim INN or Proposed INN: PYRIMETHAMINE	Weill Medical College of Cornell University	NULL	Not Recruiting			Female: yes Male: yes	40		United States;Germany;Italy

4. Primary lateral sclerosis [ 6 clinical trials, 16 drugs, (DrugBank: 8 drugs), 19 drug target genes, 32 drug target pathways]

Searched query = "Primary lateral sclerosis", "PLS"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 6 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	EUCTR2011-004798-99-DE (EUCTR)	27/02/2013	27/12/2012	Safety and Efficacy of SOD1 Inhibition By Pyrimethamine in Familial (ALS)	Safety and Efficacy of SOD1 Inhibition By Pyrimethamine in Familial (ALS) - Pyrimethamine In Familial ALS	Familial amyotrophic lateral sclerosis (FALS) MedDRA version: 14.1;Level: LLT;Classification code 10036704;Term: Primary lateral sclerosis;System Organ Class: 100000004852;Therapeutic area: Diseases [C] - Nervous System Diseases [C10]	Trade Name: Daraprim INN or Proposed INN: PYRIMETHAMINE	Weill Medical College of Cornell University	NULL	Not Recruiting			Female: yes Male: yes	40		United States;Germany;Italy