Methionine (DrugBank: Methionine)
7 diseasesID | Disease name (Link within this page) | Number of trials |
---|---|---|
34 | Neurofibromatosis | 1 |
75 | Cushing disease | 1 |
84 | Sarcoidosis | 2 |
93 | Primary biliary cholangitis [Primary biliary cirrhosis (~Mar 2017)] | 2 |
229 | Autoimmune pulmonary alveolar proteinosis | 1 |
298 | Hereditary pancreatitis | 1 |
300 | IgG4-related disease | 1 |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | EUCTR2010-019759-23-GB (EUCTR) | 12/01/2011 | 13/12/2010 | Evaluation of [11C]-methionine positron emission computerised tomography (PET CT) in diagnosing neurofibromatosis 1(NF1) - malignant peripheral nerve sheath tumours (MPNST) - Methionine PET | Evaluation of [11C]-methionine positron emission computerised tomography (PET CT) in diagnosing neurofibromatosis 1(NF1) - malignant peripheral nerve sheath tumours (MPNST) - Methionine PET | The diagnosis of malignant peripheral nerve sheath tumours in patients with neurofibromatosis 1 MedDRA version: 12;Level: LLT;Classification code 10029268;Term: Neurofibromatosis 1 associated malignant peripheral nerve sheath tumour | Product Name: [11C]-methionine INN or Proposed INN: 2-amino-4-(methyl[11C]sulfanyl)butanoic acid Other descriptive name: Methionine | Guys' and St. Thomas' NHS Foundation Trust | NULL | Not Recruiting | Female: yes Male: yes | United Kingdom |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT03346954 (ClinicalTrials.gov) | December 11, 2017 | 15/11/2017 | Impact of [11C]-Methionine PET/MRI in the Detection of Pituitary Adenomas Secreting ACTH and Causing Cushing's Disease | Impact of [11C]-Methionine PET/MRI in the Detection of Pituitary Adenomas Secreting ACTH and Causing Cushing's Disease | Cushing's Disease | Other: [11C]-Methionine PET/MRI | Hospices Civils de Lyon | NULL | Completed | 18 Years | N/A | All | 33 | N/A | France |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT02824419 (ClinicalTrials.gov) | May 2016 | 27/5/2016 | Imaging of Active Granulomas With [18F]FDG and Selected Inflammatory PET Tracers in Pulmonary Sarcoidosis | Imaging of Active Granulomas With [18F]FDG and Selected Inflammatory PET Tracers in Pulmonary Sarcoidosis | Pulmonary Sarcoidosis | Drug: Methionine;Drug: DOTANOC | Turku University Hospital | NULL | Recruiting | 18 Years | N/A | Both | 10 | Phase 2;Phase 3 | Finland |
2 | EUCTR2015-001815-11-FI (EUCTR) | 19/04/2016 | 29/12/2015 | PET imaging of pulmonary sarcoidosis | Imaging of active granulomas with [18F]FDG and selected inflammatory PET tracers in pulmonary sarcoidosis | Pulmonary sarcoidosis with active garnulomas in the lungs. The diagnosis is based on the clinical evidence or biopsy. MedDRA version: 18.1;Level: PT;Classification code 10037430;Term: Pulmonary sarcoidosis;System Organ Class: 10038738 - Respiratory, thoracic and mediastinal disorders;Therapeutic area: Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Diagnosis [E01] | Product Name: 18F-fluorodeoxyglucose Product Code: FDG INN or Proposed INN: FLUORINE (18F) FLUDEOXYGLUCOSE Product Name: C11-methionine INN or Proposed INN: L-methionine Other descriptive name: L-METHIONINE ([11C]METHYL) Product Name: 68Ga-DOTANOC INN or Proposed INN: DOTANOC Other descriptive name: DOTANOC | Turku PET Centre | NULL | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | Finland |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT02557360 (ClinicalTrials.gov) | November 2015 | 21/9/2015 | Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis | Effectiveness of S-adenosyl-L-methionine in Patients With Primary Biliary Cirrhosis | Primary Biliary Cirrhosis | Dietary Supplement: S-adenosyl-L-methionine | Pomeranian Medical University Szczecin | Laval University | Completed | N/A | N/A | All | 24 | Phase 4 | Poland |
2 | NCT00125281 (ClinicalTrials.gov) | July 25, 2005 | 29/7/2005 | SAMe to Treat Biliary Cirrhosis Symptoms | S-Adenosyl Methionine for Symptomatic Treatment of Primary Biliary Cirrhosis | Liver Cirrhosis, Biliary | Drug: S-adenosyl-methionine (SAMe) capsules | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | NULL | Terminated | 21 Years | N/A | All | 50 | Phase 2 | United States |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | NCT03887169 (ClinicalTrials.gov) | September 16, 2019 | 12/3/2019 | Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | Oral or Enteral Administration of Methionine in Patients With Pulmonary Alveolar Proteinosis by Mutation of the MARS Gene. | Pulmonary Alveolar Proteinosis;Mutation Ala393Thr of the MARS Gene;mutationSer567Leu of the MARS Gene | Drug: Methionine;Drug: Vitamin B12, B9, B6, C supplementation;Diagnostic Test: Methionine/homocysteine Dosage;Diagnostic Test: Thoracic CT scan;Diagnostic Test: Abdominal and liver ultrasound.;Diagnostic Test: Brain MRI | Assistance Publique - Hôpitaux de Paris | NULL | Completed | N/A | 18 Years | All | 3 | Phase 1;Phase 2 | France |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | EUCTR2006-000087-83-GB (EUCTR) | 19/12/2008 | 04/12/2007 | EUROPAC2 trial to investigate the efficacy of ANTOX(vers) 1.2 and MGCT (magnesiocard) for the treatment of hereditary pancreatitis and idiopathic chronic pancreatitis. - EUROPAC2 | EUROPAC2 trial to investigate the efficacy of ANTOX(vers) 1.2 and MGCT (magnesiocard) for the treatment of hereditary pancreatitis and idiopathic chronic pancreatitis. - EUROPAC2 | Hereditary Pancreatitis and Idiopathic Chronic Pancreatitis MedDRA version: 13.1;Level: HLT;Classification code 10033646;Term: Acute and chronic pancreatitis;System Organ Class: 10017947 - Gastrointestinal disorders MedDRA version: 13.1;Level: PT;Classification code 10056976;Term: Hereditary pancreatitis;System Organ Class: 10010331 - Congenital, familial and genetic disorders | Trade Name: Magnesiocard 2.5mmol Other descriptive name: MAGNESIUM ASPARTATE HYDROCHLORIDE Product Name: ANTOX (vers) 1.2 Product Code: ANTOX Other descriptive name: TOCOPHEROL INN or Proposed INN: ASCORBIC ACID Other descriptive name: SELENIUM INN or Proposed INN: METHIONINE | University of Liverpool | The Royal Liverpool and Broadgreen University Hospitals NHS Trust | Authorised-recruitment may be ongoing or finished | Female: yes Male: yes | 240 | Phase 3 | United Kingdom |
No. | TrialID | Date_ enrollment | Date_ registration | Public_title | Scientific_title | Condition | Intervention | Primary_ sponsor | Secondary_ sponsor | Recruitment_ Status | Inclusion_ agemin | Inclusion_ agemax | Inclusion_ gender | Target_ size | Phase | Countries |
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1 | JPRN-UMIN000019908 | 2016/01/01 | 01/01/2016 | Preliminary study of [11C]methionine PET/CT in the diagnosis of IgG4 related disease | IgG4 related disease | [11C]methionine PET/CT, [18F]FDG PET/CT | Saitama Medical University International Medical Center | Saitama Medical University Hospital | Complete: follow-up complete | 20years-old | Not applicable | Male and Female | 30 | Not selected | Japan |