DDrare: Database of Drug Development for Rare Diseases

Rilonacept (il-1 trap) (DrugBank: Rilonacept)

4 diseases

ID	Disease name (Link within this page)	Number of trials
51	Scleroderma	0
106	Cryopyrin-associated periodic syndrome	0
107	Juvenile idiopathic arthritis [Systemic juvenile idiopathic arthritis (~Mar 2018)]	1
266	Familial mediterranean fever	0

51. Scleroderma [ 466 clinical trials, 536 drugs, (DrugBank: 142 drugs), 110 drug target genes, 210 drug target pathways]

Searched query = "Scleroderma", "Systemic sclerosis", "SSc", "dcSSc", "lcSSc"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 466 trial found

106. Cryopyrin-associated periodic syndrome [ 39 clinical trials, 23 drugs, (DrugBank: 4 drugs), 4 drug target genes, 46 drug target pathways]

Searched query = "Cryopyrin-associated periodic syndrome", "Cryopyrin associated periodic fever syndrome", "Familial cold autoinflammatory syndrome", "FCAS", "Mucke-Wells syndrome", "MWS", "Chronic infantile neurologic cutaneous, and articular syndrome", "CINCA syndrome", "Neonatal onset multisystem inflammatory disease", "NOMID"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 39 trial found

107. Juvenile idiopathic arthritis [Systemic juvenile idiopathic arthritis (~Mar 2018)] [ 151 clinical trials, 75 drugs, (DrugBank: 13 drugs), 16 drug target genes, 90 drug target pathways]

Searched query = "Juvenile idiopathic arthritis [Systemic juvenile idiopathic arthritis (~Mar 2018)]", "Systemic-onset juvenile idiopathic arthritis", "JIA", "SJIA"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 151 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT01803321 (ClinicalTrials.gov)	November 2005	28/2/2013	Study to Evaluate the Safety and Tolerability of Two Doses of Rilonacept in Pediatric Subjects With Active Systemic Juvenile Idiopathic Arthritis (SJIA)	A Pilot, Multi-center, Randomized, Double-Blind, Placebo-Controlled, Ascending Dose, Safety, Tolerability and Preliminary Efficacy Study of Two Dose Levels of IL-1 Trap Administered Subcutaneously in Pediatric Subjects With Active Systemic Juvenile Idiopathic Arthritis (SJIA)	Systemic Juvenile Idiopathic Arthritis	Drug: rilonacept (IL-1 Trap);Other: Placebo	Regeneron Pharmaceuticals	NULL	Completed	4 Years	20 Years	Both	24	Phase 1	United States

266. Familial mediterranean fever [ 27 clinical trials, 23 drugs, (DrugBank: 6 drugs), 14 drug target genes, 57 drug target pathways]

Searched query = "Familial mediterranean fever"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 27 trial found