DDrare: Database of Drug Development for Rare Diseases

Propranolol (DrugBank: Propranolol)

5 diseases

ID	Disease name (Link within this page)	Number of trials
6	Parkinson disease	0
158	Tuberous sclerosis	1
167	Marfan syndrome	1
227	Osler disease	1
278	Huge lymphatic malformation with cervicofacial lesion	1

6. Parkinson disease [ 2,123 clinical trials, 2,046 drugs, (DrugBank: 324 drugs), 183 drug target genes, 198 drug target pathways]

Searched query = "Parkinson disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: . Trials are sorted by Date_enrollment from most recent to oldest in the table.

0 / 2,123 trial found

158. Tuberous sclerosis [ 100 clinical trials, 62 drugs, (DrugBank: 16 drugs), 35 drug target genes, 115 drug target pathways]

Searched query = "Tuberous sclerosis", "Tuberous sclerosis complex"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 100 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT02104011 (ClinicalTrials.gov)	May 22, 2015	1/4/2014	Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers	Treatment of Renal Angiomyolipomas in Tuberous Sclerosis by Beta-blockers: Pilot Trial	Renal Angiomyolipomas;Tuberous Sclerosis	Drug: Propranolol	University Hospital, Bordeaux	NULL	Completed	18 Years	N/A	All	2	Phase 2	France

167. Marfan syndrome [ 19 clinical trials, 38 drugs, (DrugBank: 10 drugs), 10 drug target genes, 49 drug target pathways]

Searched query = "Marfan syndrome"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 19 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT00651235 (ClinicalTrials.gov)	February 2007	3/3/2008	A Randomized, Open-label, LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome	A Randomized, Open-label, Active Control Trial to Evaluate the Effect of LOSARTAN Therapy on the Progression of Aortic Root Dilation in Patients With Marfan Syndrome	Marfan Syndrome	Drug: Losartan and Atenolol or Propranolol;Drug: Atenolol or Propranolol	National Taiwan University Hospital	NULL	Recruiting	1 Year	N/A	Both	44	Phase 2	Taiwan

227. Osler disease [ 49 clinical trials, 69 drugs, (DrugBank: 21 drugs), 23 drug target genes, 132 drug target pathways]

Searched query = "Osler disease", "Hereditary hemorrhagic telangiectasia", "Osler-Weber-Rendu disease"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 49 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	NCT04113187 (ClinicalTrials.gov)	June 23, 2020	27/9/2019	Propranolol for Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients	Study of the Efficacy of Propranolol for the Management of Epistaxis in Hereditary Hemorrhagic Telangiectasia Patients	Hereditary Hemorrhagic Telangiectasia;Osler Weber Rendu Disease	Drug: Propranolol treatment;Drug: Placebo	University Hospital, Bordeaux	AMRO-HHT-France - Association Maladie de Rendu-Osler	Recruiting	18 Years	N/A	All	38	Phase 3	France

278. Huge lymphatic malformation with cervicofacial lesion [ 19 clinical trials, 23 drugs, (DrugBank: 7 drugs), 5 drug target genes, 62 drug target pathways]

Searched query = "Huge lymphatic malformation with cervicofacial lesion", "Huge lymphatic malformation", "Lymphatic malformation"
The queries were searched in Public_title, Scientific_title, and Condition. Export date: 03/15/2021. Trials are sorted by Date_enrollment from most recent to oldest in the table.

1 / 19 trial found

No.	TrialID	Date_ enrollment	Date_ registration	Public_title	Scientific_title	Condition	Intervention	Primary_ sponsor	Secondary_ sponsor	Recruitment_ Status	Inclusion_ agemin	Inclusion_ agemax	Inclusion_ gender	Target_ size	Phase	Countries
1	JPRN-UMIN000008498	2012/07/25	24/07/2012	Propranolol for a treatment of lymphatic malformation		lymphatic malformation	propranolol therapy	University of Tokyo	NULL	Complete: follow-up complete	Not applicable	65years-old	Male and Female	20	Phase 2	Japan