Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト)
A B C D E F G H I J K L M N O P Q R S T U V W X Y Z other
No. | KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * | KEGG DRUG * | DrugBank | 指定難病告示番号 * |
1 | Calcium signaling pathway |
2件: EDNRA, EDNRB | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
2 | cAMP signaling pathway |
1件: EDNRA | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
3 | cGMP-PKG signaling pathway |
2件: EDNRA, EDNRB | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
1件: PDE5A | D02229 | Sildenafil | 16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 | ||
D08514 | |||||
4 | Melanogenesis |
1件: EDNRB | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
5 | Metabolic pathways |
1件: PDE5A | D02229 | Sildenafil | 16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 | |||||
6 | Neuroactive ligand-receptor interaction |
2件: EDNRA, EDNRB | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
7 | Pathways in cancer |
2件: EDNRA, EDNRB | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
8 | Purine metabolism |
1件: PDE5A | D02229 | Sildenafil | 16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 | |||||
9 | Relaxin signaling pathway |
1件: EDNRB | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
10 | Renin secretion |
1件: EDNRA | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 | |||
11 | Vascular smooth muscle contraction |
1件: EDNRA | D01227 | Bosentan | 10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 | |||||
D10135 | Macitentan | 5件: 51, 85, 86, 88, 210 |