No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PML, RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
2 | Adrenergic signaling in cardiomyocytes 6 genes, 4 drugs (DrugBank) and 20 diseases shown |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
1件: SCN5A |
D00252 |
Carbamazepine |
1件: 231 |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
3 | AMPK signaling pathway 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ADRA1A |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4 | Arachidonic acid metabolism 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
5 | C-type lectin receptor signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
6 | Calcium signaling pathway 6 genes, 2 drugs (DrugBank) and 18 diseases shown |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
7 | cAMP signaling pathway 2 genes, 2 drugs (DrugBank) and 18 diseases shown |
2件: ADRB1, ADRB2 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
8 | cGMP-PKG signaling pathway 10 genes, 3 drugs (DrugBank) and 20 diseases shown |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
1件: OPRD1 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
9 | Chemical carcinogenesis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
10 | Dilated cardiomyopathy (DCM) 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ADRB1 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
11 | Dopaminergic synapse 1 gene, 2 drugs (DrugBank) and 10 diseases shown |
1件: SCN1A |
D00252 |
Carbamazepine |
1件: 231 |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
12 | Endocytosis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
13 | Estrogen signaling pathway 2 genes, 3 drugs (DrugBank) and 13 diseases shown |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
1件: RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
14 | GABAergic synapse 16 genes, 2 drugs (DrugBank) and 10 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
15 | Gap junction 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ADRB1 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
16 | Gastric cancer 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
17 | Herpes simplex virus 1 infection 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
18 | Human cytomegalovirus infection 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
19 | Human papillomavirus infection 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
20 | IL-17 signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
21 | Influenza A 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
22 | Kaposi sarcoma-associated herpesvirus infection 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
23 | Leishmaniasis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
24 | Metabolic pathways 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
25 | MicroRNAs in cancer 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
26 | Morphine addiction 17 genes, 4 drugs (DrugBank) and 13 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
27 | Neuroactive ligand-receptor interaction 28 genes, 6 drugs (DrugBank) and 23 diseases shown |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
3件: OPRD1, OPRK1, OPRM1 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
1件: OPRM1 |
D00320 |
Fentanyl |
5件: 46, 70, 85, 215, 231 |
D01399 |
28 | NF-kappa B signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
29 | Nicotine addiction 16 genes, 2 drugs (DrugBank) and 10 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
30 | Non-small cell lung cancer 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
31 | Ovarian steroidogenesis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
32 | Oxytocin signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
33 | Pathways in cancer 4 genes, 3 drugs (DrugBank) and 20 diseases shown |
3件: PML, RARA, RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
34 | Platelet activation 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS1 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
35 | Regulation of lipolysis in adipocytes 5 genes, 4 drugs (DrugBank) and 25 diseases shown |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
36 | Renin secretion 3 genes, 2 drugs (DrugBank) and 18 diseases shown |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
37 | Retrograde endocannabinoid signaling 17 genes, 4 drugs (DrugBank) and 20 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
38 | Salivary secretion 6 genes, 2 drugs (DrugBank) and 18 diseases shown |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
39 | Serotonergic synapse 10 genes, 5 drugs (DrugBank) and 20 diseases shown |
3件: GABRB1, GABRB2, GABRB3 |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
5件: HTR3A, HTR3B, HTR3C, HTR3D, HTR3E |
D00456 |
Ondansetron |
1件: 231 |
D00678 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
40 | Small cell lung cancer 2 genes, 3 drugs (DrugBank) and 20 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
41 | Sphingolipid signaling pathway 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: OPRD1 |
D03783 |
Oxycodone |
7件: 6, 13, 46, 70, 226, 231, 298 |
D05312 |
D05462 |
42 | Taste transduction 14 genes, 5 drugs (DrugBank) and 15 diseases shown |
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00365 |
Lorazepam |
1件: 231 |
D00550 |
Midazolam |
10件: 2, 3, 6, 13, 46, 70, 96, 97, 231, 298 |
D00696 |
D05028 |
5件: HTR3A, HTR3B, HTR3C, HTR3D, HTR3E |
D00456 |
Ondansetron |
1件: 231 |
D00678 |
3件: SCN2A, SCN3A, SCN9A |
D00252 |
Carbamazepine |
1件: 231 |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
43 | Th17 cell differentiation 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
44 | Thermogenesis 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
45 | TNF signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
46 | Transcriptional misregulation in cancer 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PML, RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
47 | Ubiquitin mediated proteolysis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
48 | Vascular smooth muscle contraction 3 genes, 1 drug (DrugBank) and 9 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
49 | VEGF signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |