No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Alcoholism 2 genes, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
1件: ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
2 | Aldosterone synthesis and secretion 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PDE2A |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
3 | Apelin signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
4 | Calcium signaling pathway 5 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ADORA2A, PDE1A, PDE1B, PDE1C |
D02017 |
Theophylline |
2件: 236, 299 |
4件: ADORA2B, PDE1A, PDE1B, PDE1C |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
5 | cAMP signaling pathway 9 genes, 1 drug (DrugBank) and 2 diseases shown |
9件: ADORA1, ADORA2A, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D02017 |
Theophylline |
2件: 236, 299 |
8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
6 | cGMP-PKG signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ADORA1, PDE2A, PDE3A, PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
7 | Cortisol synthesis and secretion 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
8 | Cushing syndrome 3 genes, 1 drug (DrugBank) and 2 diseases shown |
3件: PDE11A, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
9 | Cytokine-cytokine receptor interaction 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
10 | Glucagon signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
11 | Growth hormone synthesis, secretion and action 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
12 | Insulin signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
13 | JAK-STAT signaling pathway 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
14 | Metabolic pathways 16 genes, 1 drug (DrugBank) and 2 diseases shown |
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
15 | Morphine addiction 17 genes, 1 drug (DrugBank) and 2 diseases shown |
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
16 | Neuroactive ligand-receptor interaction 4 genes, 2 drugs (DrugBank) and 18 diseases shown |
2件: ADORA1, ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
2件: ADORA1, ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
17 | Olfactory transduction 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: PDE1A, PDE1B, PDE1C, PDE2A |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
18 | Parathyroid hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
19 | Parkinson disease 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
20 | PI3K-Akt signaling pathway 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
21 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
22 | Purine metabolism 16 genes, 1 drug (DrugBank) and 2 diseases shown |
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
23 | Rap1 signaling pathway 2 genes, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
1件: ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
24 | Regulation of lipolysis in adipocytes 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: ADORA1, PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
25 | Renin secretion 6 genes, 1 drug (DrugBank) and 2 diseases shown |
6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
26 | Sphingolipid signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA1 |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
27 | Taste transduction 3 genes, 1 drug (DrugBank) and 2 diseases shown |
3件: PDE1A, PDE1B, PDE1C |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
28 | Vascular smooth muscle contraction 2 genes, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
1件: ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |