No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | ABC transporters 2 genes, 5 drugs (DrugBank) and 2 diseases shown |
1件: ABCC8 |
D00594 |
Repaglinide |
2件: 6, 299 |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
2 | Acute myeloid leukemia 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: RARA |
D04162 |
Fenretinide |
1件: 299 |
3 | Adherens junction 2 genes, 3 drugs (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
4 | Adipocytokine signaling pathway 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
5 | Adrenergic signaling in cardiomyocytes 7 genes, 6 drugs (DrugBank) and 28 diseases shown |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: SCN5A |
D08407 |
Pramocaine |
1件: 299 |
6 | AGE-RAGE signaling pathway in diabetic complications 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
7 | Alcoholism 2 genes, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
1件: ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
8 | Aldosterone synthesis and secretion 6 genes, 3 drugs (DrugBank) and 19 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: PDE2A |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
9 | Aldosterone-regulated sodium reabsorption 8 genes, 4 drugs (DrugBank) and 3 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
3件: SCNN1A, SCNN1B, SCNN1G |
D00649 |
Amiloride |
3件: 13, 225, 299 |
D07447 |
10 | Alzheimer disease 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
11 | Amoebiasis 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
12 | Amphetamine addiction 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
13 | AMPK signaling pathway 7 genes, 12 drugs (DrugBank) and 43 diseases shown |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
14 | Amyotrophic lateral sclerosis (ALS) 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
15 | Apelin signaling pathway 4 genes, 3 drugs (DrugBank) and 31 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
16 | Arachidonic acid metabolism 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: PTGS1, PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
17 | Asthma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: FCER1A |
D05251 |
Omalizumab |
6件: 53, 65, 98, 162, 226, 299 |
18 | Autophagy - animal 3 genes, 2 drugs (DrugBank) and 21 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
19 | Axon guidance 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
20 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
21 | Bile secretion 7 genes, 9 drugs (DrugBank) and 35 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: NR1H4 |
D00734 |
Ursodeoxycholic acid |
12件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 |
22 | Breast cancer 5 genes, 6 drugs (DrugBank) and 14 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
D05209 |
Norgestimate |
1件: 299 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
23 | C-type lectin receptor signaling pathway 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
24 | Calcium signaling pathway 15 genes, 8 drugs (DrugBank) and 47 diseases shown |
4件: ADORA2A, PDE1A, PDE1B, PDE1C |
D02017 |
Theophylline |
2件: 236, 299 |
4件: ADORA2B, PDE1A, PDE1B, PDE1C |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: CHRM2, CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
25 | cAMP signaling pathway 16 genes, 11 drugs (DrugBank) and 18 diseases shown |
9件: ADORA1, ADORA2A, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D02017 |
Theophylline |
2件: 236, 299 |
8件: ADORA1, PDE10A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
1件: CHRM2 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
26 | Carbohydrate digestion and absorption 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
27 | Cardiac muscle contraction 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
28 | Cellular senescence 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
29 | cGMP-PKG signaling pathway 20 genes, 12 drugs (DrugBank) and 54 diseases shown |
4件: ADORA1, PDE2A, PDE3A, PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02731 |
Vardenafil |
3件: 13, 86, 299 |
D03260 |
D08668 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
30 | Chagas disease (American trypanosomiasis) 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
31 | Chemical carcinogenesis 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
32 | Chemokine signaling pathway 3 genes, 2 drugs (DrugBank) and 5 diseases shown |
2件: CXCR1, CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
33 | Cholinergic synapse 2 genes, 1 drug (DrugBank) and 3 diseases shown |
2件: CHRM2, CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
34 | Circadian entrainment 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
35 | Circadian rhythm 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
36 | Collecting duct acid secretion 2 genes, 3 drugs (DrugBank) and 20 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
37 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: SERPINC1 |
D07510 |
Heparin |
11件: 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 |
38 | Cortisol synthesis and secretion 3 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
39 | Cushing syndrome 4 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
3件: PDE11A, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
40 | Cytokine-cytokine receptor interaction 10 genes, 8 drugs (DrugBank) and 42 diseases shown |
1件: CSF2RA |
D05066 |
Molgramostim |
2件: 229, 299 |
2件: CXCR1, CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
41 | Dopaminergic synapse 4 genes, 2 drugs (DrugBank) and 30 diseases shown |
3件: PPP3CA, PPP3CB, PPP3CC |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SCN1A |
D08407 |
Pramocaine |
1件: 299 |
42 | EGFR tyrosine kinase inhibitor resistance 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
43 | Endocrine and other factor-regulated calcium reabsorption 6 genes, 6 drugs (DrugBank) and 18 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: ESR1 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
1件: VDR |
D00122 |
Calcifediol |
2件: 113, 299 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
44 | Endocrine resistance 3 genes, 3 drugs (DrugBank) and 10 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
45 | Endocytosis 4 genes, 3 drugs (DrugBank) and 9 diseases shown |
2件: CXCR1, CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
46 | Epithelial cell signaling in Helicobacter pylori infection 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: CXCR1, CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
47 | Estrogen signaling pathway 4 genes, 5 drugs (DrugBank) and 5 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
D05209 |
Norgestimate |
1件: 299 |
1件: RARA |
D04162 |
Fenretinide |
1件: 299 |
48 | Fc epsilon RI signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: FCER1A |
D05251 |
Omalizumab |
6件: 53, 65, 98, 162, 226, 299 |
49 | Fluid shear stress and atherosclerosis 4 genes, 2 drugs (DrugBank) and 29 diseases shown |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
50 | Focal adhesion 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
51 | FoxO signaling pathway 4 genes, 4 drugs (DrugBank) and 21 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
52 | Gap junction 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
53 | Gastric acid secretion 8 genes, 9 drugs (DrugBank) and 21 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
1件: CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
54 | Gastric cancer 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: RARB |
D04162 |
Fenretinide |
1件: 299 |
55 | Glioma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
56 | Glucagon signaling pathway 8 genes, 3 drugs (DrugBank) and 41 diseases shown |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
57 | Glutamatergic synapse 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
58 | GnRH secretion 2 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
1件: KCNJ11 |
D00594 |
Repaglinide |
2件: 6, 299 |
59 | Growth hormone synthesis, secretion and action 1 gene, 2 drugs (DrugBank) and 20 diseases shown |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
60 | Hematopoietic cell lineage 3 genes, 2 drugs (DrugBank) and 18 diseases shown |
1件: CSF2RA |
D05066 |
Molgramostim |
2件: 229, 299 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
61 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
62 | Herpes simplex virus 1 infection 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
63 | HIF-1 signaling pathway 4 genes, 4 drugs (DrugBank) and 11 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
64 | Human cytomegalovirus infection 9 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
65 | Human immunodeficiency virus 1 infection 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
66 | Human papillomavirus infection 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
67 | Human T-cell leukemia virus 1 infection 8 genes, 4 drugs (DrugBank) and 44 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
68 | Huntington disease 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
69 | Hypertrophic cardiomyopathy (HCM) 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
70 | IL-17 signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
71 | Inflammatory bowel disease (IBD) 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
72 | Inflammatory mediator regulation of TRP channels 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
73 | Influenza A 3 genes, 3 drugs (DrugBank) and 19 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
74 | Insulin resistance 3 genes, 3 drugs (DrugBank) and 17 diseases shown |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
75 | Insulin secretion 7 genes, 3 drugs (DrugBank) and 3 diseases shown |
2件: ABCC8, KCNJ11 |
D00594 |
Repaglinide |
2件: 6, 299 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
76 | Insulin signaling pathway 4 genes, 4 drugs (DrugBank) and 18 diseases shown |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
77 | Intestinal immune network for IgA production 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
78 | JAK-STAT signaling pathway 4 genes, 4 drugs (DrugBank) and 26 diseases shown |
1件: CSF2RA |
D05066 |
Molgramostim |
2件: 229, 299 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
79 | Kaposi sarcoma-associated herpesvirus infection 7 genes, 3 drugs (DrugBank) and 34 diseases shown |
1件: IFNGR1 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
80 | Leishmaniasis 3 genes, 2 drugs (DrugBank) and 11 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
81 | Leukocyte transendothelial migration 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
82 | Long-term depression 4 genes, 2 drugs (DrugBank) and 11 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
83 | Long-term potentiation 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
84 | Longevity regulating pathway 5 genes, 5 drugs (DrugBank) and 26 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
85 | Longevity regulating pathway - multiple species 4 genes, 4 drugs (DrugBank) and 21 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
86 | MAPK signaling pathway 8 genes, 5 drugs (DrugBank) and 42 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
87 | Melanoma 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
88 | Metabolic pathways 27 genes, 15 drugs (DrugBank) and 52 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02731 |
Vardenafil |
3件: 13, 86, 299 |
D03260 |
D08668 |
2件: PTGS1, PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
1件: UGCG |
D05032 |
Miglustat |
3件: 19, 256, 299 |
89 | MicroRNAs in cancer 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
90 | Mineral absorption 6 genes, 5 drugs (DrugBank) and 18 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: CLCN2 |
D04790 |
Lubiprostone |
4件: 6, 13, 290, 299 |
1件: VDR |
D00122 |
Calcifediol |
2件: 113, 299 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
91 | Morphine addiction 17 genes, 2 drugs (DrugBank) and 3 diseases shown |
17件: ADORA1, PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
92 | mTOR signaling pathway 4 genes, 4 drugs (DrugBank) and 21 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
93 | Natural killer cell mediated cytotoxicity 7 genes, 2 drugs (DrugBank) and 33 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
94 | Necroptosis 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
95 | Neuroactive ligand-receptor interaction 10 genes, 17 drugs (DrugBank) and 85 diseases shown |
2件: ADORA1, ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
2件: ADORA1, ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: CHRM2, CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
1件: CNR2 |
D11312 |
Ajulemic acid |
3件: 50, 51, 299 |
1件: GHR |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: NR3C1 |
D00246 |
Budesonide |
10件: 66, 85, 93, 94, 95, 96, 97, 98, 228, 299 |
D00292 |
Dexamethasone |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D07981 |
Fluticasone |
4件: 98, 228, 299, 306 |
D01708 |
Fluticasone propionate |
4件: 98, 228, 299, 306 |
D00088 |
Hydrocortisone |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
D00165 |
Hydrocortisone acetate |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
96 | NF-kappa B signaling pathway 3 genes, 3 drugs (DrugBank) and 23 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
97 | Non-alcoholic fatty liver disease (NAFLD) 3 genes, 3 drugs (DrugBank) and 17 diseases shown |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
98 | Non-small cell lung cancer 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: RARB |
D04162 |
Fenretinide |
1件: 299 |
99 | Olfactory transduction 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: PDE1A, PDE1B, PDE1C, PDE2A |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
100 | Oocyte meiosis 7 genes, 4 drugs (DrugBank) and 33 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
D05209 |
Norgestimate |
1件: 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
101 | Osteoclast differentiation 10 genes, 5 drugs (DrugBank) and 52 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
102 | Ovarian steroidogenesis 3 genes, 4 drugs (DrugBank) and 10 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
103 | Oxidative phosphorylation 2 genes, 3 drugs (DrugBank) and 20 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
104 | Oxytocin signaling pathway 11 genes, 4 drugs (DrugBank) and 43 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
105 | Pancreatic secretion 6 genes, 6 drugs (DrugBank) and 3 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
1件: CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
106 | Parathyroid hormone synthesis, secretion and action 6 genes, 6 drugs (DrugBank) and 22 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
1件: VDR |
D00122 |
Calcifediol |
2件: 113, 299 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
107 | Parkinson disease 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
108 | Pathogenic Escherichia coli infection 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
109 | Pathways in cancer 12 genes, 10 drugs (DrugBank) and 39 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
1件: CSF2RA |
D05066 |
Molgramostim |
2件: 229, 299 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
2件: RARA, RARB |
D04162 |
Fenretinide |
1件: 299 |
110 | PD-L1 expression and PD-1 checkpoint pathway in cancer 7 genes, 2 drugs (DrugBank) and 33 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
111 | Phospholipase D signaling pathway 5 genes, 5 drugs (DrugBank) and 23 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
2件: CXCR1, CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
1件: FCER1A |
D05251 |
Omalizumab |
6件: 53, 65, 98, 162, 226, 299 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
112 | PI3K-Akt signaling pathway 6 genes, 6 drugs (DrugBank) and 32 diseases shown |
1件: CHRM2 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: GHR, IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
113 | Platelet activation 4 genes, 2 drugs (DrugBank) and 11 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PTGS1 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
114 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
115 | Progesterone-mediated oocyte maturation 3 genes, 4 drugs (DrugBank) and 10 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
1件: PGR |
D00182 |
Norethisterone |
4件: 13, 46, 49, 299 |
D00953 |
D05209 |
Norgestimate |
1件: 299 |
116 | Prolactin signaling pathway 3 genes, 3 drugs (DrugBank) and 10 diseases shown |
1件: ESR1 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
2件: ESR1, ESR2 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
117 | Prostate cancer 2 genes, 2 drugs (DrugBank) and 21 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
118 | Protein digestion and absorption 5 genes, 3 drugs (DrugBank) and 3 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: DPP4 |
D08996 |
Saxagliptin |
1件: 299 |
D08516 |
Sitagliptin |
3件: 75, 233, 299 |
119 | Proteoglycans in cancer 2 genes, 3 drugs (DrugBank) and 10 diseases shown |
1件: ESR1 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
120 | Proximal tubule bicarbonate reclamation 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
121 | Purine metabolism 20 genes, 5 drugs (DrugBank) and 20 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
16件: PDE10A, PDE11A, PDE1A, PDE1B, PDE1C, PDE2A, PDE3A, PDE3B, PDE4A, PDE4B, PDE4C, PDE4D, PDE7A, PDE7B, PDE8A, PDE8B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02731 |
Vardenafil |
3件: 13, 86, 299 |
D03260 |
D08668 |
122 | Rap1 signaling pathway 4 genes, 4 drugs (DrugBank) and 7 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
1件: ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
123 | Ras signaling pathway 2 genes, 3 drugs (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
124 | Regulation of actin cytoskeleton 3 genes, 2 drugs (DrugBank) and 6 diseases shown |
2件: CHRM2, CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
125 | Regulation of lipolysis in adipocytes 6 genes, 7 drugs (DrugBank) and 18 diseases shown |
2件: ADORA1, PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
2件: PTGS1, PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
126 | Renin secretion 16 genes, 7 drugs (DrugBank) and 48 diseases shown |
6件: ADORA1, PDE1A, PDE1B, PDE1C, PDE3A, PDE3B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
127 | Renin-angiotensin system 1 gene, 1 drug (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
128 | Retrograde endocannabinoid signaling 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
129 | Rheumatoid arthritis 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: TNFSF11 |
D03684 |
Denosumab |
7件: 46, 50, 93, 95, 96, 274, 299 |
130 | Salivary secretion 9 genes, 6 drugs (DrugBank) and 20 diseases shown |
1件: ADRB2 |
D01373 |
Formoterol |
4件: 85, 228, 299, 306 |
D05277 |
D07990 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
D00687 |
Salmeterol |
1件: 299 |
D05792 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
131 | Salmonella infection 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
132 | Serotonergic synapse 3 genes, 2 drugs (DrugBank) and 8 diseases shown |
2件: PTGS1, PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
1件: SLC6A4 |
D00809 |
Amitriptyline |
3件: 78, 226, 299 |
D07448 |
133 | Shigellosis 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
134 | Signaling pathways regulating pluripotency of stem cells 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
135 | Small cell lung cancer 2 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
1件: RARB |
D04162 |
Fenretinide |
1件: 299 |
136 | Sphingolipid metabolism 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: UGCG |
D05032 |
Miglustat |
3件: 19, 256, 299 |
137 | Sphingolipid signaling pathway 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: ADORA1 |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
1件: FCER1A |
D05251 |
Omalizumab |
6件: 53, 65, 98, 162, 226, 299 |
138 | Synaptic vesicle cycle 2 genes, 1 drug (DrugBank) and 3 diseases shown |
2件: SLC6A2, SLC6A4 |
D00809 |
Amitriptyline |
3件: 78, 226, 299 |
D07448 |
139 | T cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
140 | Taste transduction 10 genes, 4 drugs (DrugBank) and 6 diseases shown |
1件: CHRM3 |
D00525 |
Pilocarpine |
3件: 6, 53, 299 |
D02200 |
D05478 |
3件: PDE1A, PDE1B, PDE1C |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D02017 |
D06103 |
D06104 |
3件: SCN2A, SCN3A, SCN9A |
D08407 |
Pramocaine |
1件: 299 |
3件: SCNN1A, SCNN1B, SCNN1G |
D00649 |
Amiloride |
3件: 13, 225, 299 |
D07447 |
141 | Terpenoid backbone biosynthesis 2 genes, 5 drugs (DrugBank) and 36 diseases shown |
1件: FDPS |
D00939 |
Alendronic acid |
7件: 19, 41, 46, 50, 271, 274, 299 |
D07119 |
D01968 |
Zoledronic acid |
11件: 6, 13, 46, 65, 93, 95, 96, 271, 274, 299, 333 |
D06378 |
D06379 |
D08689 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D01915 |
Rosuvastatin |
8件: 6, 46, 49, 51, 79, 96, 271, 299 |
D08492 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
142 | Th1 and Th2 cell differentiation 7 genes, 2 drugs (DrugBank) and 33 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
143 | Th17 cell differentiation 9 genes, 4 drugs (DrugBank) and 42 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RARA |
D04162 |
Fenretinide |
1件: 299 |
144 | Thermogenesis 3 genes, 2 drugs (DrugBank) and 25 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
145 | Thyroid cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
146 | Thyroid hormone signaling pathway 5 genes, 3 drugs (DrugBank) and 5 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
1件: ESR1 |
D00105 |
Estradiol |
5件: 13, 46, 49, 226, 299 |
D01413 |
D01617 |
D01953 |
D04061 |
D04063 |
D04064 |
D04065 |
D00554 |
Ethinylestradiol |
4件: 13, 46, 49, 299 |
147 | Thyroid hormone synthesis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00297 |
Digitoxin |
1件: 299 |
148 | Tight junction 3 genes, 5 drugs (DrugBank) and 17 diseases shown |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
149 | TNF signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
150 | Toxoplasmosis 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
151 | Transcriptional misregulation in cancer 4 genes, 4 drugs (DrugBank) and 27 diseases shown |
1件: IGF1R |
D03297 |
Mecasermin |
6件: 65, 78, 96, 168, 265, 299 |
D04870 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
1件: RARA |
D04162 |
Fenretinide |
1件: 299 |
152 | Tuberculosis 8 genes, 5 drugs (DrugBank) and 39 diseases shown |
2件: IFNGR1, IFNGR2 |
D00747 |
Interferon gamma-1b |
7件: 65, 85, 90, 228, 299, 301, 326 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: VDR |
D00122 |
Calcifediol |
2件: 113, 299 |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
153 | Type II diabetes mellitus 3 genes, 3 drugs (DrugBank) and 2 diseases shown |
2件: ABCC8, KCNJ11 |
D00594 |
Repaglinide |
2件: 6, 299 |
1件: INSR |
D04539 |
Insulin Detemir |
1件: 299 |
D03250 |
Insulin glargine |
1件: 299 |
154 | Vascular smooth muscle contraction 6 genes, 3 drugs (DrugBank) and 24 diseases shown |
1件: ADORA2A |
D02017 |
Theophylline |
2件: 236, 299 |
1件: ADORA2B |
D00371 |
Theophylline |
2件: 236, 299 |
D01712 |
D06103 |
D06104 |
1件: AGTR1 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
155 | VEGF signaling pathway 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00126 |
Ibuprofen |
6件: 13, 46, 65, 113, 271, 299 |
D01122 |
D04490 |
D06606 |
156 | Vibrio cholerae infection 1 gene, 4 drugs (DrugBank) and 1 disease shown |
1件: CFTR |
D11507 |
Elexacaftor |
1件: 299 |
D09916 |
Ivacaftor |
1件: 299 |
D10134 |
Lumacaftor |
1件: 299 |
D11041 |
Tezacaftor |
1件: 299 |
157 | Viral protein interaction with cytokine and cytokine receptor 3 genes, 2 drugs (DrugBank) and 5 diseases shown |
2件: CXCR1, CXCR2 |
D08984 |
Reparixin |
2件: 298, 299 |
1件: CXCR4 |
D08971 |
Plerixafor |
4件: 51, 65, 285, 299 |
158 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |