No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Alzheimer disease 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
2 | Amphetamine addiction 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
3 | Amyotrophic lateral sclerosis (ALS) 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
4 | Axon guidance 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
5 | B cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
6 | Breast cancer 2 genes, 1 drug (DrugBank) and 4 diseases shown |
2件: ESR1, PGR |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
7 | C-type lectin receptor signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
8 | Calcium signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
9 | Cellular senescence 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
10 | cGMP-PKG signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
11 | Complement and coagulation cascades 2 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: F8 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
1件: VWF |
D11160 |
Caplacizumab |
1件: 64 |
12 | Dopaminergic synapse 3 genes, 1 drug (DrugBank) and 44 diseases shown |
3件: PPP3CA, PPP3CB, PPP3CC |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
13 | ECM-receptor interaction 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: VWF |
D11160 |
Caplacizumab |
1件: 64 |
14 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: ESR1 |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
15 | Endocrine resistance 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: ESR1 |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
16 | Estrogen signaling pathway 2 genes, 1 drug (DrugBank) and 4 diseases shown |
2件: ESR1, PGR |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
17 | Focal adhesion 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: VWF |
D11160 |
Caplacizumab |
1件: 64 |
18 | Glucagon signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
19 | Glutamatergic synapse 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
20 | Hematopoietic cell lineage 1 gene, 1 drug (DrugBank) and 42 diseases shown |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
21 | Human cytomegalovirus infection 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
22 | Human immunodeficiency virus 1 infection 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
23 | Human papillomavirus infection 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: VWF |
D11160 |
Caplacizumab |
1件: 64 |
24 | Human T-cell leukemia virus 1 infection 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
25 | Kaposi sarcoma-associated herpesvirus infection 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
26 | Long-term potentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
27 | MAPK signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
28 | Natural killer cell mediated cytotoxicity 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
29 | Neuroactive ligand-receptor interaction 2 genes, 4 drugs (DrugBank) and 58 diseases shown |
1件: AVPR2 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
1件: NR3C1 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
30 | Oocyte meiosis 7 genes, 2 drugs (DrugBank) and 44 diseases shown |
2件: AR, PGR |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
31 | Osteoclast differentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
32 | Oxytocin signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
33 | Pathways in cancer 2 genes, 1 drug (DrugBank) and 4 diseases shown |
2件: AR, ESR1 |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
34 | PD-L1 expression and PD-1 checkpoint pathway in cancer 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
35 | Phospholipase D signaling pathway 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AVPR2 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
36 | PI3K-Akt signaling pathway 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: VWF |
D11160 |
Caplacizumab |
1件: 64 |
37 | Platelet activation 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: VWF |
D11160 |
Caplacizumab |
1件: 64 |
38 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: PGR |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
39 | Prolactin signaling pathway 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: ESR1 |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
40 | Prostate cancer 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: AR |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
41 | Proteoglycans in cancer 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: ESR1 |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
42 | Renin secretion 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
43 | T cell receptor signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
44 | Th1 and Th2 cell differentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
45 | Th17 cell differentiation 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
46 | Thyroid hormone signaling pathway 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: ESR1 |
D00289 |
Danazol |
4件: 60, 64, 65, 285 |
47 | Tuberculosis 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
48 | Vasopressin-regulated water reabsorption 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AVPR2 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
49 | VEGF signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
50 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 44 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |