No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 5 genes, 4 drugs (DrugBank) and 41 diseases shown |
4件: BRAF, FLT3, KIT, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2 | Adherens junction 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3 | Adipocytokine signaling pathway 3 genes, 2 drugs (DrugBank) and 46 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
4 | Adrenergic signaling in cardiomyocytes 12 genes, 8 drugs (DrugBank) and 30 diseases shown |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: SCN5A |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
5 | AGE-RAGE signaling pathway in diabetic complications 2 genes, 2 drugs (DrugBank) and 15 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
6 | Alcoholism 3 genes, 3 drugs (DrugBank) and 4 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: DRD2 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
D01348 |
Terguride |
2件: 51, 86 |
7 | Aldosterone synthesis and secretion 5 genes, 3 drugs (DrugBank) and 10 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
8 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: NR3C2 |
D00443 |
Spironolactone |
6件: 58, 67, 86, 113, 218, 225 |
9 | Alzheimer disease 9 genes, 3 drugs (DrugBank) and 33 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
10 | Amoebiasis 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
11 | Amphetamine addiction 7 genes, 3 drugs (DrugBank) and 33 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
12 | AMPK signaling pathway 6 genes, 6 drugs (DrugBank) and 59 diseases shown |
1件: ADRA1A |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: HMGCR |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
13 | Amyotrophic lateral sclerosis (ALS) 6 genes, 2 drugs (DrugBank) and 30 diseases shown |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
14 | Apelin signaling pathway 5 genes, 4 drugs (DrugBank) and 48 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
15 | Apoptosis 5 genes, 3 drugs (DrugBank) and 2 diseases shown |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
3件: PARP1, PARP2, PARP3 |
D09730 |
Olaparib |
1件: 86 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
16 | Arachidonic acid metabolism 2 genes, 2 drugs (DrugBank) and 16 diseases shown |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
17 | Arrhythmogenic right ventricular cardiomyopathy (ARVC) 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
18 | Autophagy - animal 4 genes, 3 drugs (DrugBank) and 46 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
19 | Autophagy - other 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
20 | Axon guidance 7 genes, 4 drugs (DrugBank) and 38 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
21 | B cell receptor signaling pathway 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
22 | Base excision repair 3 genes, 1 drug (DrugBank) and 1 disease shown |
3件: PARP1, PARP2, PARP3 |
D09730 |
Olaparib |
1件: 86 |
23 | Bile secretion 1 gene, 1 drug (DrugBank) and 19 diseases shown |
1件: HMGCR |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
24 | Bladder cancer 4 genes, 3 drugs (DrugBank) and 10 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
25 | Breast cancer 8 genes, 8 drugs (DrugBank) and 45 diseases shown |
4件: BRAF, FLT4, KIT, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: ESR1, ESR2 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
26 | C-type lectin receptor signaling pathway 7 genes, 4 drugs (DrugBank) and 39 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
27 | Calcium signaling pathway 29 genes, 21 drugs (DrugBank) and 57 diseases shown |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: AVPR1A |
D01236 |
Conivaptan |
1件: 86 |
D07748 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
4件: CHRM1, CHRM2, CHRM3, CHRM5 |
D02212 |
Ipratropium |
2件: 6, 86 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D07171 |
Sitaxentan |
1件: 86 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: HRH1 |
D00300 |
Diphenhydramine |
5件: 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
1件: HRH2 |
D00318 |
Famotidine |
3件: 6, 46, 86 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: PDGFRB |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: TBXA2R |
D04500 |
Ifetroban |
3件: 51, 86, 113 |
28 | cAMP signaling pathway 12 genes, 14 drugs (DrugBank) and 31 diseases shown |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
2件: ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
2件: CHRM1, CHRM2 |
D02212 |
Ipratropium |
2件: 6, 86 |
1件: DRD2 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
D01348 |
Terguride |
2件: 51, 86 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
D07171 |
Sitaxentan |
1件: 86 |
29 | Carbohydrate digestion and absorption 1 gene, 2 drugs (DrugBank) and 4 diseases shown |
1件: CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
30 | Cardiac muscle contraction 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
31 | Cell cycle 1 gene, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
32 | Cellular senescence 8 genes, 5 drugs (DrugBank) and 52 diseases shown |
1件: CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
33 | Central carbon metabolism in cancer 8 genes, 5 drugs (DrugBank) and 41 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
5件: FLT3, KIT, PDGFRB, RAF1, RET |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
34 | cGMP-PKG signaling pathway 26 genes, 18 drugs (DrugBank) and 56 diseases shown |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D07171 |
Sitaxentan |
1件: 86 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
D10027 |
Udenafil |
1件: 86 |
D02731 |
Vardenafil |
3件: 13, 86, 299 |
D03260 |
D08668 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
35 | Chagas disease (American trypanosomiasis) 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: ACE |
D00251 |
Captopril |
2件: 17, 86 |
36 | Chemical carcinogenesis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
37 | Chemokine signaling pathway 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
38 | Choline metabolism in cancer 5 genes, 5 drugs (DrugBank) and 41 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
39 | Cholinergic synapse 9 genes, 3 drugs (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
D02212 |
Ipratropium |
2件: 6, 86 |
40 | Chronic myeloid leukemia 3 genes, 3 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
41 | Circadian entrainment 5 genes, 3 drugs (DrugBank) and 9 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
42 | Circadian rhythm 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
43 | Cocaine addiction 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: DRD2 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
D01348 |
Terguride |
2件: 51, 86 |
44 | Collecting duct acid secretion 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
45 | Colorectal cancer 4 genes, 3 drugs (DrugBank) and 36 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
46 | Cortisol synthesis and secretion 5 genes, 3 drugs (DrugBank) and 10 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
47 | Cushing syndrome 7 genes, 5 drugs (DrugBank) and 14 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: BRAF |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
48 | Cytokine-cytokine receptor interaction 5 genes, 4 drugs (DrugBank) and 26 diseases shown |
1件: ACVR2A |
D09670 |
Sotatercept |
2件: 86, 284 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
49 | Dilated cardiomyopathy (DCM) 5 genes, 5 drugs (DrugBank) and 15 diseases shown |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
50 | Dopaminergic synapse 9 genes, 6 drugs (DrugBank) and 38 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: DRD2 |
D01348 |
Terguride |
2件: 51, 86 |
3件: DRD2, DRD3, DRD4 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
3件: PPP3CA, PPP3CB, PPP3CC |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: SCN1A |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
51 | Drug metabolism - other enzymes 2 genes, 2 drugs (DrugBank) and 12 diseases shown |
1件: HPRT1 |
D00161 |
Mercaptopurine |
5件: 86, 94, 96, 97, 164 |
D04931 |
1件: RRM2 |
D00341 |
Hydroxyurea |
8件: 3, 13, 19, 20, 65, 85, 86, 284 |
52 | EGFR tyrosine kinase inhibitor resistance 9 genes, 7 drugs (DrugBank) and 52 diseases shown |
4件: BRAF, KDR, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
53 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 3 drugs (DrugBank) and 8 diseases shown |
1件: ESR1 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
54 | Endocrine resistance 6 genes, 6 drugs (DrugBank) and 40 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: ESR1, ESR2 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
55 | Endocytosis 2 genes, 3 drugs (DrugBank) and 14 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
56 | Endometrial cancer 3 genes, 2 drugs (DrugBank) and 5 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
57 | Epithelial cell signaling in Helicobacter pylori infection 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
58 | ErbB signaling pathway 5 genes, 5 drugs (DrugBank) and 41 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
59 | Estrogen signaling pathway 5 genes, 6 drugs (DrugBank) and 15 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: ESR1, ESR2 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: OPRM1 |
D00842 |
Morphine |
4件: 36, 46, 70, 86 |
D02271 |
D08233 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
60 | Fc epsilon RI signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
61 | Fc gamma R-mediated phagocytosis 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
62 | Fluid shear stress and atherosclerosis 9 genes, 7 drugs (DrugBank) and 38 diseases shown |
1件: ACVR2A |
D09670 |
Sotatercept |
2件: 86, 284 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: KDR |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
63 | Focal adhesion 8 genes, 5 drugs (DrugBank) and 16 diseases shown |
5件: BRAF, FLT4, KDR, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
64 | FoxO signaling pathway 5 genes, 3 drugs (DrugBank) and 21 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
65 | GABAergic synapse 4 genes, 2 drugs (DrugBank) and 4 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
66 | Gap junction 9 genes, 10 drugs (DrugBank) and 26 diseases shown |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: DRD2 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
D01348 |
Terguride |
2件: 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
67 | Gastric acid secretion 4 genes, 3 drugs (DrugBank) and 6 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
1件: CHRM3 |
D02212 |
Ipratropium |
2件: 6, 86 |
1件: HRH2 |
D00318 |
Famotidine |
3件: 6, 46, 86 |
68 | Gastric cancer 4 genes, 3 drugs (DrugBank) and 36 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
69 | Glioma 6 genes, 5 drugs (DrugBank) and 41 diseases shown |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
70 | Glucagon signaling pathway 7 genes, 2 drugs (DrugBank) and 40 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
71 | Glutamatergic synapse 7 genes, 3 drugs (DrugBank) and 33 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
72 | Glutathione metabolism 2 genes, 2 drugs (DrugBank) and 8 diseases shown |
1件: ANPEP |
D00087 |
Ubenimex |
1件: 86 |
1件: RRM2 |
D00341 |
Hydroxyurea |
8件: 3, 13, 19, 20, 65, 85, 86, 284 |
73 | GnRH secretion 6 genes, 6 drugs (DrugBank) and 12 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: ESR2 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
74 | GnRH signaling pathway 6 genes, 4 drugs (DrugBank) and 8 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
75 | Growth hormone synthesis, secretion and action 6 genes, 4 drugs (DrugBank) and 39 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
76 | Hematopoietic cell lineage 7 genes, 7 drugs (DrugBank) and 60 diseases shown |
1件: ANPEP |
D00087 |
Ubenimex |
1件: 86 |
2件: FLT3, KIT |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
77 | Hepatitis B 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
78 | Hepatitis C 3 genes, 2 drugs (DrugBank) and 5 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
79 | Hepatocellular carcinoma 5 genes, 4 drugs (DrugBank) and 36 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
80 | Herpes simplex virus 1 infection 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
81 | HIF-1 signaling pathway 4 genes, 4 drugs (DrugBank) and 48 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
82 | Human cytomegalovirus infection 13 genes, 11 drugs (DrugBank) and 72 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
83 | Human immunodeficiency virus 1 infection 7 genes, 3 drugs (DrugBank) and 49 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
84 | Human papillomavirus infection 6 genes, 7 drugs (DrugBank) and 46 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
85 | Human T-cell leukemia virus 1 infection 7 genes, 2 drugs (DrugBank) and 39 diseases shown |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
86 | Huntington disease 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
87 | Hypertrophic cardiomyopathy (HCM) 7 genes, 4 drugs (DrugBank) and 21 diseases shown |
1件: ACE |
D00251 |
Captopril |
2件: 17, 86 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
88 | IL-17 signaling pathway 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
89 | Inflammatory mediator regulation of TRP channels 3 genes, 3 drugs (DrugBank) and 23 diseases shown |
1件: HRH1 |
D00300 |
Diphenhydramine |
5件: 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TRPV1 |
D00250 |
Capsaicin |
6件: 2, 6, 19, 86, 113, 226 |
90 | Influenza A 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
91 | Insulin resistance 3 genes, 2 drugs (DrugBank) and 46 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
92 | Insulin secretion 5 genes, 3 drugs (DrugBank) and 5 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: CHRM3 |
D02212 |
Ipratropium |
2件: 6, 86 |
93 | Insulin signaling pathway 5 genes, 3 drugs (DrugBank) and 46 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
94 | JAK-STAT signaling pathway 7 genes, 7 drugs (DrugBank) and 51 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
95 | Kaposi sarcoma-associated herpesvirus infection 9 genes, 6 drugs (DrugBank) and 57 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
96 | Leishmaniasis 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
97 | Long-term depression 5 genes, 2 drugs (DrugBank) and 7 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
98 | Long-term potentiation 8 genes, 4 drugs (DrugBank) and 34 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: CACNA1C |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
99 | Longevity regulating pathway 4 genes, 3 drugs (DrugBank) and 50 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
100 | Longevity regulating pathway - multiple species 3 genes, 2 drugs (DrugBank) and 46 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
101 | MAPK signaling pathway 21 genes, 10 drugs (DrugBank) and 53 diseases shown |
7件: BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
102 | Melanogenesis 3 genes, 5 drugs (DrugBank) and 19 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: KIT, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
103 | Melanoma 5 genes, 4 drugs (DrugBank) and 14 diseases shown |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
104 | Metabolic pathways 13 genes, 13 drugs (DrugBank) and 49 diseases shown |
1件: ANPEP |
D00087 |
Ubenimex |
1件: 86 |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
1件: CYP19A1 |
D00960 |
Anastrozole |
3件: 78, 86, 193 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: HMGCR |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: HPRT1 |
D00161 |
Mercaptopurine |
5件: 86, 94, 96, 97, 164 |
D04931 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
D10027 |
Udenafil |
1件: 86 |
D02731 |
Vardenafil |
3件: 13, 86, 299 |
D03260 |
D08668 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RRM2 |
D00341 |
Hydroxyurea |
8件: 3, 13, 19, 20, 65, 85, 86, 284 |
105 | MicroRNAs in cancer 8 genes, 8 drugs (DrugBank) and 48 diseases shown |
2件: ABL1, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: ABL1, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
106 | Morphine addiction 1 gene, 1 drug (DrugBank) and 4 diseases shown |
1件: OPRM1 |
D00842 |
Morphine |
4件: 36, 46, 70, 86 |
D02271 |
D08233 |
107 | mTOR signaling pathway 5 genes, 3 drugs (DrugBank) and 46 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
108 | Natural killer cell mediated cytotoxicity 7 genes, 2 drugs (DrugBank) and 31 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
109 | Necroptosis 3 genes, 1 drug (DrugBank) and 1 disease shown |
3件: PARP1, PARP2, PARP3 |
D09730 |
Olaparib |
1件: 86 |
110 | Neuroactive ligand-receptor interaction 31 genes, 26 drugs (DrugBank) and 70 diseases shown |
9件: ADRA1A, ADRA1B, ADRA1D, ADRA2A, ADRA2B, ADRA2C, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
2件: AVPR1A, AVPR2 |
D01236 |
Conivaptan |
1件: 86 |
D07748 |
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
D02212 |
Ipratropium |
2件: 6, 86 |
3件: DRD2, DRD3, DRD4 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
2件: DRD2, PRL |
D01348 |
Terguride |
2件: 51, 86 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D07171 |
Sitaxentan |
1件: 86 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: HRH1 |
D00300 |
Diphenhydramine |
5件: 49, 51, 70, 86, 256 |
D00669 |
D02419 |
D03285 |
D03360 |
D03854 |
1件: HRH2 |
D00318 |
Famotidine |
3件: 6, 46, 86 |
1件: NR3C1 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
1件: OPRM1 |
D00842 |
Morphine |
4件: 36, 46, 70, 86 |
D02271 |
D08233 |
1件: PTGIR |
D02720 |
Beraprost |
1件: 86 |
D00106 |
Epoprostenol |
1件: 86 |
D01337 |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D10725 |
Ralinepag |
1件: 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
1件: TBXA2R |
D04500 |
Ifetroban |
3件: 51, 86, 113 |
1件: TRPV1 |
D00250 |
Capsaicin |
6件: 2, 6, 19, 86, 113, 226 |
111 | Neurotrophin signaling pathway 4 genes, 4 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
112 | NF-kappa B signaling pathway 3 genes, 4 drugs (DrugBank) and 29 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: PARP1 |
D09730 |
Olaparib |
1件: 86 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
113 | Non-alcoholic fatty liver disease (NAFLD) 4 genes, 3 drugs (DrugBank) and 30 diseases shown |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
114 | Non-small cell lung cancer 3 genes, 2 drugs (DrugBank) and 5 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
115 | Oocyte meiosis 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
1件: AR |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
116 | Osteoclast differentiation 7 genes, 3 drugs (DrugBank) and 47 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
117 | Ovarian steroidogenesis 2 genes, 3 drugs (DrugBank) and 18 diseases shown |
1件: CYP19A1 |
D00960 |
Anastrozole |
3件: 78, 86, 193 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
118 | Oxidative phosphorylation 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: ATP4A, ATP4B |
D01984 |
Esomeprazole |
6件: 6, 46, 86, 98, 298, 299 |
D04056 |
D07917 |
D09339 |
119 | Oxytocin signaling pathway 17 genes, 9 drugs (DrugBank) and 54 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
120 | p53 signaling pathway 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: RRM2 |
D00341 |
Hydroxyurea |
8件: 3, 13, 19, 20, 65, 85, 86, 284 |
121 | Pancreatic cancer 5 genes, 4 drugs (DrugBank) and 38 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
122 | Pancreatic secretion 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: CHRM3 |
D02212 |
Ipratropium |
2件: 6, 86 |
123 | Parathyroid hormone synthesis, secretion and action 3 genes, 2 drugs (DrugBank) and 5 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
124 | Parkinson disease 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: DRD2 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
D01348 |
Terguride |
2件: 51, 86 |
125 | Pathogenic Escherichia coli infection 2 genes, 3 drugs (DrugBank) and 27 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
126 | Pathways in cancer 22 genes, 19 drugs (DrugBank) and 72 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
3件: AR, ESR1, ESR2 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D07171 |
Sitaxentan |
1件: 86 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: ESR1, ESR2 |
D01161 |
Fulvestrant |
1件: 86 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
127 | PD-L1 expression and PD-1 checkpoint pathway in cancer 8 genes, 4 drugs (DrugBank) and 49 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
128 | Phospholipase D signaling pathway 9 genes, 7 drugs (DrugBank) and 43 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
2件: AVPR1A, AVPR2 |
D01236 |
Conivaptan |
1件: 86 |
D07748 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
3件: KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
129 | PI3K-Akt signaling pathway 16 genes, 10 drugs (DrugBank) and 61 diseases shown |
2件: CHRM1, CHRM2 |
D02212 |
Ipratropium |
2件: 6, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
130 | Platelet activation 7 genes, 11 drugs (DrugBank) and 21 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: P2RY12 |
D00769 |
Clopidogrel |
2件: 49, 86 |
D07729 |
D10823 |
D10824 |
1件: PTGIR |
D02720 |
Beraprost |
1件: 86 |
D00106 |
Epoprostenol |
1件: 86 |
D01337 |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D10725 |
Ralinepag |
1件: 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
1件: PTGS1 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: TBXA2R |
D04500 |
Ifetroban |
3件: 51, 86, 113 |
131 | Platinum drug resistance 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
132 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
133 | Progesterone-mediated oocyte maturation 2 genes, 1 drug (DrugBank) and 2 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
134 | Prolactin signaling pathway 4 genes, 5 drugs (DrugBank) and 10 diseases shown |
2件: ESR1, ESR2 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: PRL |
D01348 |
Terguride |
2件: 51, 86 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
135 | Prostate cancer 8 genes, 7 drugs (DrugBank) and 54 diseases shown |
1件: AR |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
136 | Protein processing in endoplasmic reticulum 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
137 | Proteoglycans in cancer 7 genes, 7 drugs (DrugBank) and 41 diseases shown |
3件: BRAF, KDR, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: ESR1 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
138 | Purine metabolism 6 genes, 7 drugs (DrugBank) and 28 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: HPRT1 |
D00161 |
Mercaptopurine |
5件: 86, 94, 96, 97, 164 |
D04931 |
1件: PDE5A |
D02229 |
Sildenafil |
16件: 6, 46, 50, 51, 85, 86, 96, 113, 210, 211, 212, 225, 226, 278, 294, 299 |
D08514 |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
D10027 |
Udenafil |
1件: 86 |
D02731 |
Vardenafil |
3件: 13, 86, 299 |
D03260 |
D08668 |
1件: RRM2 |
D00341 |
Hydroxyurea |
8件: 3, 13, 19, 20, 65, 85, 86, 284 |
139 | Pyrimidine metabolism 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: RRM2 |
D00341 |
Hydroxyurea |
8件: 3, 13, 19, 20, 65, 85, 86, 284 |
140 | Rap1 signaling pathway 10 genes, 7 drugs (DrugBank) and 16 diseases shown |
6件: BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: DRD2 |
D01462 |
Lisuride |
2件: 6, 86 |
D08132 |
D01348 |
Terguride |
2件: 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
141 | Ras signaling pathway 10 genes, 5 drugs (DrugBank) and 16 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
142 | Regulation of actin cytoskeleton 10 genes, 5 drugs (DrugBank) and 14 diseases shown |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
5件: CHRM1, CHRM2, CHRM3, CHRM4, CHRM5 |
D02212 |
Ipratropium |
2件: 6, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
143 | Regulation of lipolysis in adipocytes 5 genes, 6 drugs (DrugBank) and 27 diseases shown |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
2件: ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
144 | Relaxin signaling pathway 4 genes, 5 drugs (DrugBank) and 16 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
145 | Renal cell carcinoma 3 genes, 2 drugs (DrugBank) and 9 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
146 | Renin secretion 18 genes, 14 drugs (DrugBank) and 51 diseases shown |
1件: ACE |
D00251 |
Captopril |
2件: 17, 86 |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
2件: ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
3件: ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
D07171 |
Sitaxentan |
1件: 86 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
147 | Renin-angiotensin system 4 genes, 3 drugs (DrugBank) and 7 diseases shown |
1件: ACE |
D00251 |
Captopril |
2件: 17, 86 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: ANPEP |
D00087 |
Ubenimex |
1件: 86 |
148 | Retrograde endocannabinoid signaling 5 genes, 4 drugs (DrugBank) and 18 diseases shown |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
149 | Rheumatoid arthritis 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
150 | Salivary secretion 10 genes, 6 drugs (DrugBank) and 24 diseases shown |
5件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2 |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
6件: ADRA1A, ADRA1B, ADRA1D, ADRB1, ADRB2, ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: ADRB1 |
D00634 |
Bisoprolol |
3件: 67, 86, 113 |
D02342 |
1件: ADRB2 |
D02147 |
Salbutamol |
13件: 3, 11, 12, 13, 49, 85, 86, 89, 113, 228, 231, 256, 299 |
1件: CHRM3 |
D02212 |
Ipratropium |
2件: 6, 86 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
151 | Serotonergic synapse 9 genes, 6 drugs (DrugBank) and 22 diseases shown |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: SLC6A4 |
D00326 |
Fluoxetine |
6件: 13, 17, 78, 86, 179, 206 |
D00823 |
152 | Shigellosis 4 genes, 5 drugs (DrugBank) and 51 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
153 | Signaling pathways regulating pluripotency of stem cells 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: ACVR2A |
D09670 |
Sotatercept |
2件: 86, 284 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
154 | Small cell lung cancer 1 gene, 2 drugs (DrugBank) and 16 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
155 | Sphingolipid signaling pathway 2 genes, 2 drugs (DrugBank) and 2 diseases shown |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
156 | Steroid hormone biosynthesis 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: CYP19A1 |
D00960 |
Anastrozole |
3件: 78, 86, 193 |
157 | Synaptic vesicle cycle 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: SLC6A4 |
D00326 |
Fluoxetine |
6件: 13, 17, 78, 86, 179, 206 |
D00823 |
158 | T cell receptor signaling pathway 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
159 | Taste transduction 5 genes, 4 drugs (DrugBank) and 13 diseases shown |
1件: CACNA1C |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: CHRM3 |
D02212 |
Ipratropium |
2件: 6, 86 |
3件: SCN2A, SCN3A, SCN9A |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
160 | Terpenoid backbone biosynthesis 1 gene, 1 drug (DrugBank) and 19 diseases shown |
1件: HMGCR |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
161 | TGF-beta signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: ACVR2A |
D09670 |
Sotatercept |
2件: 86, 284 |
162 | Th1 and Th2 cell differentiation 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
163 | Th17 cell differentiation 8 genes, 4 drugs (DrugBank) and 62 diseases shown |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
164 | Thermogenesis 6 genes, 5 drugs (DrugBank) and 53 diseases shown |
1件: ADRB3 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
165 | Thyroid cancer 3 genes, 2 drugs (DrugBank) and 18 diseases shown |
2件: BRAF, RET |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
166 | Thyroid hormone signaling pathway 3 genes, 5 drugs (DrugBank) and 40 diseases shown |
1件: ESR1 |
D01161 |
Fulvestrant |
1件: 86 |
D08409 |
Prasterone |
6件: 49, 53, 83, 86, 96, 113 |
D00966 |
Tamoxifen |
4件: 2, 86, 113, 227 |
D08559 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
167 | Tight junction 4 genes, 4 drugs (DrugBank) and 20 diseases shown |
1件: CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
168 | TNF signaling pathway 2 genes, 3 drugs (DrugBank) and 16 diseases shown |
1件: MAP3K5 |
D10988 |
Selonsertib |
1件: 86 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
169 | Transcriptional misregulation in cancer 3 genes, 3 drugs (DrugBank) and 27 diseases shown |
1件: FLT3 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: PPARG |
D00945 |
Pioglitazone |
17件: 2, 6, 13, 15, 20, 46, 49, 65, 67, 78, 81, 86, 96, 229, 265, 298, 299 |
D08378 |
170 | Tuberculosis 6 genes, 2 drugs (DrugBank) and 31 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
171 | Type II diabetes mellitus 3 genes, 3 drugs (DrugBank) and 39 diseases shown |
2件: CACNA1C, CACNA1D |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
172 | Ubiquitin mediated proteolysis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KEAP1 |
D03846 |
Dimethyl fumarate |
5件: 13, 46, 49, 51, 86 |
173 | Vascular smooth muscle contraction 16 genes, 18 drugs (DrugBank) and 30 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D00255 |
Carvedilol |
4件: 6, 57, 86, 113 |
D03415 |
D00095 |
Epinephrine |
9件: 6, 13, 46, 86, 96, 168, 226, 231, 256 |
D00996 |
D02149 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: AVPR1A |
D01236 |
Conivaptan |
1件: 86 |
D07748 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
4件: CACNA1C, CACNA1D, CACNA1F, CACNA1S |
D00616 |
Diltiazem |
3件: 58, 86, 130 |
D03830 |
D07845 |
D00617 |
Nicardipine |
2件: 70, 86 |
D08270 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
D10135 |
Macitentan |
5件: 51, 85, 86, 88, 210 |
D07171 |
Sitaxentan |
1件: 86 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PTGIR |
D02720 |
Beraprost |
1件: 86 |
D00106 |
Epoprostenol |
1件: 86 |
D01337 |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D10725 |
Ralinepag |
1件: 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
174 | Vasopressin-regulated water reabsorption 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: AVPR2 |
D01236 |
Conivaptan |
1件: 86 |
D07748 |
175 | VEGF signaling pathway 9 genes, 5 drugs (DrugBank) and 44 diseases shown |
2件: KDR, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
176 | Viral myocarditis 1 gene, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
177 | Viral protein interaction with cytokine and cytokine receptor 1 gene, 1 drug (DrugBank) and 16 diseases shown |
1件: IL6R |
D02596 |
Tocilizumab |
16件: 2, 13, 40, 41, 43, 46, 50, 51, 53, 54, 55, 86, 107, 266, 271, 331 |
178 | Wnt signaling pathway 5 genes, 1 drug (DrugBank) and 30 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |