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 Target Gene/Pathway(薬物標的遺伝子/パスウェイリスト) 

   e.g. "Sirolimus", "アダリムマブ", "MAP2K"

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20 / 275 pathways found* Show info (disease name, etc.) on mouse-over.
 No.   KEGG PATHWAY
 On map, Yellow: Drug target, Red: Disease-related 
 KEGG GENES  KEGG DRUG  DrugBank   指定難病告示番号
 1  Alcoholism 
 3 genes, 2 drugs (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 2件: DRD1, DRD2   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 2  Amphetamine addiction 
 2 genes, 2 drugs (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 1件: DRD1   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 3  Calcium signaling pathway 
 2 genes, 1 drug (DrugBank) and 7 diseases shown 
 2件: DRD1, DRD5   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 4  cAMP signaling pathway 
 3 genes, 1 drug (DrugBank) and 7 diseases shown 
 3件: DRD1, DRD2, DRD5   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 5  Cocaine addiction 
 3 genes, 2 drugs (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 2件: DRD1, DRD2   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 6  Dopaminergic synapse 
 6 genes, 2 drugs (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 5件: DRD1, DRD2, DRD3, DRD4, DRD5   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 7  GABAergic synapse 
 16 genes, 1 drug (DrugBank) and 2 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   2件: 201, 206 
 8  Gap junction 
 2 genes, 1 drug (DrugBank) and 7 diseases shown 
 2件: DRD1, DRD2   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 9  Metabolic pathways 
 1 gene, 1 drug (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 10  Morphine addiction 
 17 genes, 2 drugs (DrugBank) and 8 diseases shown 
 1件: DRD1   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   2件: 201, 206 
 11  Neuroactive ligand-receptor interaction 
 21 genes, 2 drugs (DrugBank) and 8 diseases shown 
 5件: DRD1, DRD2, DRD3, DRD4, DRD5   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   2件: 201, 206 
 12  Nicotine addiction 
 16 genes, 1 drug (DrugBank) and 2 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   2件: 201, 206 
 13  Parkinson disease 
 2 genes, 1 drug (DrugBank) and 7 diseases shown 
 2件: DRD1, DRD2   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 14  Phenylalanine metabolism 
 1 gene, 1 drug (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 15  Rap1 signaling pathway 
 1 gene, 1 drug (DrugBank) and 7 diseases shown 
 1件: DRD2   D00059   Levodopa   7件: 2, 4, 6, 17, 90, 164, 201 
 16  Retrograde endocannabinoid signaling 
 16 genes, 1 drug (DrugBank) and 2 diseases shown 
 16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ   D04282   Gaboxadol   2件: 201, 206 
 17  Serotonergic synapse 
 4 genes, 2 drugs (DrugBank) and 9 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 3件: GABRB1, GABRB2, GABRB3   D04282   Gaboxadol   2件: 201, 206 
 18  Taste transduction 
 6 genes, 1 drug (DrugBank) and 2 diseases shown 
 6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6   D04282   Gaboxadol   2件: 201, 206 
 19  Tryptophan metabolism 
 1 gene, 1 drug (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 
 20  Tyrosine metabolism 
 1 gene, 1 drug (DrugBank) and 8 diseases shown 
 1件: DDC   D00558   Carbidopa   8件: 2, 4, 6, 13, 17, 90, 164, 201 

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