No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2 | Adipocytokine signaling pathway 2 genes, 3 drugs (DrugBank) and 51 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3 | Adrenergic signaling in cardiomyocytes 6 genes, 5 drugs (DrugBank) and 24 diseases shown |
1件: AGTR1 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
4 | African trypanosomiasis 4 genes, 2 drugs (DrugBank) and 21 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
5 | AGE-RAGE signaling pathway in diabetic complications 13 genes, 8 drugs (DrugBank) and 38 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
6 | Alanine, aspartate and glutamate metabolism 4 genes, 1 drug (DrugBank) and 14 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
7 | Aldosterone synthesis and secretion 5 genes, 7 drugs (DrugBank) and 44 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
8 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: NR3C2 |
D10528 |
Aldosterone |
1件: 222 |
9 | Allograft rejection 5 genes, 4 drugs (DrugBank) and 34 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
10 | Alzheimer disease 7 genes, 5 drugs (DrugBank) and 60 diseases shown |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
11 | Amoebiasis 7 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
12 | Amphetamine addiction 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
13 | AMPK signaling pathway 3 genes, 4 drugs (DrugBank) and 49 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00892 |
Fluvastatin |
3件: 79, 218, 222 |
D07983 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
14 | Amyotrophic lateral sclerosis (ALS) 10 genes, 6 drugs (DrugBank) and 60 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
15 | Antifolate resistance 3 genes, 2 drugs (DrugBank) and 21 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
16 | Antigen processing and presentation 1 gene, 2 drugs (DrugBank) and 21 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
17 | Apelin signaling pathway 2 genes, 5 drugs (DrugBank) and 50 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
18 | Apoptosis 1 gene, 2 drugs (DrugBank) and 21 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
19 | Asthma 3 genes, 3 drugs (DrugBank) and 21 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
20 | Autoimmune thyroid disease 4 genes, 3 drugs (DrugBank) and 28 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
21 | Autophagy - animal 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
22 | Autophagy - other 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
23 | Axon guidance 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
24 | B cell receptor signaling pathway 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
25 | beta-Alanine metabolism 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: ABAT, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
26 | Bile secretion 1 gene, 2 drugs (DrugBank) and 18 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00892 |
Fluvastatin |
3件: 79, 218, 222 |
D07983 |
27 | Breast cancer 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
28 | Butanoate metabolism 4 genes, 1 drug (DrugBank) and 14 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
29 | C-type lectin receptor signaling pathway 13 genes, 6 drugs (DrugBank) and 60 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
30 | Calcium signaling pathway 10 genes, 9 drugs (DrugBank) and 74 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
31 | cAMP signaling pathway 1 gene, 2 drugs (DrugBank) and 14 diseases shown |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
32 | Cell adhesion molecules (CAMs) 3 genes, 2 drugs (DrugBank) and 24 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
33 | Cell cycle 3 genes, 1 drug (DrugBank) and 4 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
34 | Cellular senescence 15 genes, 7 drugs (DrugBank) and 73 diseases shown |
2件: IL1A, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
35 | Central carbon metabolism in cancer 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
36 | cGMP-PKG signaling pathway 6 genes, 7 drugs (DrugBank) and 65 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
37 | Chagas disease (American trypanosomiasis) 13 genes, 6 drugs (DrugBank) and 26 diseases shown |
1件: ACE |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00624 |
Perindopril |
2件: 167, 222 |
D03753 |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
38 | Chemokine signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: CCL2 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
39 | Cholesterol metabolism 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: PCSK9 |
D10557 |
Evolocumab |
2件: 79, 222 |
40 | Choline metabolism in cancer 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
41 | Chronic myeloid leukemia 3 genes, 1 drug (DrugBank) and 4 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
42 | Circadian entrainment 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
43 | Collecting duct acid secretion 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: ATP4A, ATP4B |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
44 | Colorectal cancer 4 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
45 | Complement and coagulation cascades 2 genes, 2 drugs (DrugBank) and 9 diseases shown |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
1件: C5AR1 |
D11093 |
Avacopan |
4件: 43, 44, 222, 223 |
46 | Cortisol synthesis and secretion 5 genes, 7 drugs (DrugBank) and 44 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
47 | Cushing syndrome 5 genes, 7 drugs (DrugBank) and 44 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
48 | Cytokine-cytokine receptor interaction 12 genes, 6 drugs (DrugBank) and 30 diseases shown |
6件: CCL2, IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
49 | Cytosolic DNA-sensing pathway 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
50 | Dilated cardiomyopathy (DCM) 4 genes, 3 drugs (DrugBank) and 22 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
51 | Dopaminergic synapse 7 genes, 4 drugs (DrugBank) and 55 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: PPP3CA, PPP3CB, PPP3CC |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
52 | Drug metabolism - other enzymes 2 genes, 3 drugs (DrugBank) and 36 diseases shown |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
53 | EGFR tyrosine kinase inhibitor resistance 3 genes, 3 drugs (DrugBank) and 44 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
54 | Endocrine resistance 5 genes, 2 drugs (DrugBank) and 37 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
55 | Endocytosis 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
56 | Epithelial cell signaling in Helicobacter pylori infection 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
57 | Epstein-Barr virus infection 8 genes, 5 drugs (DrugBank) and 23 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
58 | ErbB signaling pathway 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
59 | Fc epsilon RI signaling pathway 5 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
60 | Fluid shear stress and atherosclerosis 8 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: CCL2, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
61 | FoxO signaling pathway 9 genes, 3 drugs (DrugBank) and 12 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
62 | GABAergic synapse 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: ABAT, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
63 | Gastric acid secretion 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: ATP4A, ATP4B |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
64 | Gastric cancer 4 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
65 | Glioma 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
66 | Glucagon signaling pathway 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
67 | Glutamatergic synapse 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
68 | GnRH secretion 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
69 | GnRH signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
70 | Graft-versus-host disease 6 genes, 3 drugs (DrugBank) and 34 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
71 | Growth hormone synthesis, secretion and action 5 genes, 2 drugs (DrugBank) and 37 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
72 | Hematopoietic cell lineage 7 genes, 5 drugs (DrugBank) and 55 diseases shown |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
73 | Hepatitis B 10 genes, 5 drugs (DrugBank) and 24 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
74 | Hepatitis C 2 genes, 3 drugs (DrugBank) and 22 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
75 | Hepatocellular carcinoma 4 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
76 | Herpes simplex virus 1 infection 7 genes, 5 drugs (DrugBank) and 56 diseases shown |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
77 | HIF-1 signaling pathway 2 genes, 2 drugs (DrugBank) and 41 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
78 | Hippo signaling pathway 3 genes, 1 drug (DrugBank) and 4 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
79 | Human cytomegalovirus infection 15 genes, 8 drugs (DrugBank) and 76 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
80 | Human immunodeficiency virus 1 infection 11 genes, 7 drugs (DrugBank) and 76 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
81 | Human papillomavirus infection 3 genes, 4 drugs (DrugBank) and 52 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
82 | Human T-cell leukemia virus 1 infection 13 genes, 9 drugs (DrugBank) and 60 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
83 | Huntington disease 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
84 | Hypertrophic cardiomyopathy (HCM) 6 genes, 5 drugs (DrugBank) and 26 diseases shown |
1件: ACE |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00624 |
Perindopril |
2件: 167, 222 |
D03753 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
85 | IL-17 signaling pathway 8 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
86 | Inflammatory bowel disease (IBD) 8 genes, 3 drugs (DrugBank) and 22 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
87 | Inflammatory mediator regulation of TRP channels 5 genes, 2 drugs (DrugBank) and 11 diseases shown |
1件: IL1B |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
88 | Influenza A 6 genes, 3 drugs (DrugBank) and 22 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
89 | Insulin resistance 3 genes, 3 drugs (DrugBank) and 51 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
90 | Insulin signaling pathway 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
91 | Intestinal immune network for IgA production 7 genes, 5 drugs (DrugBank) and 30 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
92 | JAK-STAT signaling pathway 5 genes, 4 drugs (DrugBank) and 44 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
93 | Kaposi sarcoma-associated herpesvirus infection 13 genes, 8 drugs (DrugBank) and 78 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
94 | Legionellosis 3 genes, 2 drugs (DrugBank) and 21 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
95 | Leishmaniasis 12 genes, 5 drugs (DrugBank) and 24 diseases shown |
4件: IL10, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
96 | Leukocyte transendothelial migration 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
97 | Long-term potentiation 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
98 | Longevity regulating pathway 2 genes, 2 drugs (DrugBank) and 39 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
99 | Longevity regulating pathway - multiple species 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
100 | Malaria 9 genes, 4 drugs (DrugBank) and 22 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
101 | MAPK signaling pathway 18 genes, 8 drugs (DrugBank) and 68 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
102 | Measles 5 genes, 3 drugs (DrugBank) and 17 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
103 | Metabolic pathways 10 genes, 8 drugs (DrugBank) and 61 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
2件: ATP4A, ATP4B |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00892 |
Fluvastatin |
3件: 79, 218, 222 |
D07983 |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
104 | MicroRNAs in cancer 2 genes, 2 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TGFB2 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
105 | mTOR signaling pathway 2 genes, 3 drugs (DrugBank) and 51 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
106 | Natural killer cell mediated cytotoxicity 6 genes, 5 drugs (DrugBank) and 60 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
107 | Necroptosis 4 genes, 3 drugs (DrugBank) and 22 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
108 | Neuroactive ligand-receptor interaction 6 genes, 12 drugs (DrugBank) and 76 diseases shown |
1件: AGTR1 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
1件: C5AR1 |
D11093 |
Avacopan |
4件: 43, 44, 222, 223 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
D00284 |
Tetracosactide |
5件: 78, 83, 113, 145, 222 |
1件: NR3C1 |
D00292 |
Dexamethasone |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
109 | Neurotrophin signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
110 | NF-kappa B signaling pathway 4 genes, 4 drugs (DrugBank) and 26 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
111 | Nicotinate and nicotinamide metabolism 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
112 | NOD-like receptor signaling pathway 9 genes, 4 drugs (DrugBank) and 23 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
113 | Non-alcoholic fatty liver disease (NAFLD) 5 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
114 | Oocyte meiosis 9 genes, 4 drugs (DrugBank) and 55 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
115 | Osteoclast differentiation 16 genes, 9 drugs (DrugBank) and 62 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
2件: TGFB1, TGFB2 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
116 | Oxidative phosphorylation 2 genes, 1 drug (DrugBank) and 6 diseases shown |
2件: ATP4A, ATP4B |
D00355 |
Lansoprazole |
6件: 63, 71, 98, 166, 222, 299 |
117 | Oxytocin signaling pathway 6 genes, 4 drugs (DrugBank) and 55 diseases shown |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
118 | Pancreatic cancer 5 genes, 3 drugs (DrugBank) and 40 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
119 | Pancreatic secretion 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
120 | Pathogenic Escherichia coli infection 7 genes, 3 drugs (DrugBank) and 22 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
121 | Pathways in cancer 9 genes, 10 drugs (DrugBank) and 57 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
122 | PD-L1 expression and PD-1 checkpoint pathway in cancer 11 genes, 6 drugs (DrugBank) and 73 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
123 | Pertussis 10 genes, 4 drugs (DrugBank) and 28 diseases shown |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
124 | Phospholipase D signaling pathway 2 genes, 5 drugs (DrugBank) and 50 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
125 | PI3K-Akt signaling pathway 4 genes, 4 drugs (DrugBank) and 44 diseases shown |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
126 | Platelet activation 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
127 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
128 | Primary immunodeficiency 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
129 | Prion diseases 4 genes, 2 drugs (DrugBank) and 16 diseases shown |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
130 | Progesterone-mediated oocyte maturation 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
131 | Prolactin signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
132 | Propanoate metabolism 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: ABAT |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
133 | Prostate cancer 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
134 | Proteoglycans in cancer 8 genes, 5 drugs (DrugBank) and 53 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
2件: TGFB1, TGFB2 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
135 | Purine metabolism 2 genes, 3 drugs (DrugBank) and 36 diseases shown |
2件: IMPDH1, IMPDH2 |
D01392 |
Mizoribine |
8件: 46, 49, 51, 53, 66, 94, 222, 224 |
D00752 |
Mycophenolate mofetil |
32件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 85, 95, 96, 162, 164, 222, 224, 226, 234, 283, 284, 285, 300 |
D05094 |
D05095 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
136 | Rap1 signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
137 | Relaxin signaling pathway 5 genes, 2 drugs (DrugBank) and 5 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
138 | Renal cell carcinoma 3 genes, 1 drug (DrugBank) and 4 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
139 | Renin secretion 8 genes, 10 drugs (DrugBank) and 65 diseases shown |
1件: ACE |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00624 |
Perindopril |
2件: 167, 222 |
D03753 |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: REN |
D03208 |
Aliskiren |
3件: 66, 167, 222 |
140 | Renin-angiotensin system 4 genes, 7 drugs (DrugBank) and 24 diseases shown |
1件: ACE |
D00362 |
Lisinopril |
5件: 46, 66, 67, 113, 222 |
D08131 |
D00624 |
Perindopril |
2件: 167, 222 |
D03753 |
1件: AGTR1 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
2件: AGTR1, AGTR2 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
1件: REN |
D03208 |
Aliskiren |
3件: 66, 167, 222 |
141 | Retrograde endocannabinoid signaling 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
142 | Rheumatoid arthritis 11 genes, 5 drugs (DrugBank) and 36 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
1件: TNFSF13B |
D03068 |
Belimumab |
8件: 11, 43, 44, 46, 49, 51, 53, 222 |
143 | RIG-I-like receptor signaling pathway 5 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
144 | Salivary secretion 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: CD38 |
D10777 |
Daratumumab |
2件: 28, 222 |
145 | Salmonella infection 7 genes, 2 drugs (DrugBank) and 11 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
146 | Shigellosis 7 genes, 4 drugs (DrugBank) and 52 diseases shown |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
147 | Signaling pathways regulating pluripotency of stem cells 5 genes, 2 drugs (DrugBank) and 7 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
148 | Sphingolipid signaling pathway 5 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
149 | Staphylococcus aureus infection 3 genes, 3 drugs (DrugBank) and 18 diseases shown |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
1件: C5AR1 |
D11093 |
Avacopan |
4件: 43, 44, 222, 223 |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
150 | Systemic lupus erythematosus 6 genes, 5 drugs (DrugBank) and 38 diseases shown |
1件: C5 |
D03940 |
Eculizumab |
7件: 11, 13, 14, 62, 109, 222, 223 |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
151 | T cell receptor signaling pathway 11 genes, 6 drugs (DrugBank) and 60 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
152 | Taurine and hypotaurine metabolism 2 genes, 1 drug (DrugBank) and 14 diseases shown |
2件: GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
153 | Terpenoid backbone biosynthesis 1 gene, 2 drugs (DrugBank) and 18 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
D00892 |
Fluvastatin |
3件: 79, 218, 222 |
D07983 |
154 | TGF-beta signaling pathway 4 genes, 3 drugs (DrugBank) and 22 diseases shown |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
155 | Th1 and Th2 cell differentiation 11 genes, 6 drugs (DrugBank) and 56 diseases shown |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
156 | Th17 cell differentiation 15 genes, 9 drugs (DrugBank) and 74 diseases shown |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
1件: TGFB1 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
157 | Thermogenesis 6 genes, 3 drugs (DrugBank) and 40 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
158 | Thyroid cancer 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
159 | Thyroid hormone signaling pathway 1 gene, 1 drug (DrugBank) and 36 diseases shown |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
160 | TNF signaling pathway 8 genes, 3 drugs (DrugBank) and 22 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
161 | Toll-like receptor signaling pathway 10 genes, 5 drugs (DrugBank) and 35 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
162 | Toxoplasmosis 11 genes, 6 drugs (DrugBank) and 24 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
163 | Transcriptional misregulation in cancer 4 genes, 4 drugs (DrugBank) and 30 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
164 | Tuberculosis 18 genes, 8 drugs (DrugBank) and 60 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
3件: TGFB1, TGFB2, TGFB3 |
D09620 |
Fresolimumab |
4件: 51, 85, 222, 274 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
165 | Type I diabetes mellitus 7 genes, 4 drugs (DrugBank) and 45 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
166 | Type II diabetes mellitus 3 genes, 4 drugs (DrugBank) and 58 diseases shown |
1件: CACNA1G |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: MTOR |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
167 | Valine, leucine and isoleucine degradation 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: ABAT |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
168 | Vascular smooth muscle contraction 1 gene, 4 drugs (DrugBank) and 24 diseases shown |
1件: AGTR1 |
D00150 |
Angiotensin II |
7件: 17, 19, 46, 66, 86, 222, 224 |
D02014 |
D00523 |
Irbesartan |
4件: 66, 167, 168, 222 |
D00357 |
Losartan |
18件: 13, 17, 19, 46, 58, 66, 67, 85, 96, 97, 98, 113, 164, 167, 179, 215, 222, 299 |
D08146 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
169 | VEGF signaling pathway 9 genes, 4 drugs (DrugBank) and 55 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
170 | Viral carcinogenesis 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: JAK1 |
D10871 |
Filgotinib |
6件: 46, 53, 96, 97, 222, 271 |
171 | Viral myocarditis 3 genes, 2 drugs (DrugBank) and 24 diseases shown |
1件: CD40 |
D11357 |
Bleselumab |
1件: 222 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
172 | Viral protein interaction with cytokine and cytokine receptor 5 genes, 3 drugs (DrugBank) and 24 diseases shown |
4件: CCL2, IL10, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL2RA |
D03058 |
Basiliximab |
7件: 2, 50, 65, 66, 97, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
173 | Wnt signaling pathway 5 genes, 3 drugs (DrugBank) and 55 diseases shown |
5件: PPP3CA, PPP3CB, PPP3CC, PPP3R1, PPP3R2 |
D00184 |
Ciclosporin |
44件: 11, 14, 19, 20, 26, 28, 36, 38, 39, 40, 41, 42, 45, 46, 49, 50, 53, 55, 56, 58, 60, 61, 62, 63, 64, 65, 90, 95, 97, 113, 162, 164, 222, 223, 226, 228, 234, 269, 274, 283, 284, 285, 302, 326 |
D00107 |
Tacrolimus |
30件: 2, 11, 13, 36, 46, 49, 50, 51, 53, 60, 61, 62, 65, 66, 85, 86, 95, 96, 97, 113, 151, 158, 164, 222, 224, 226, 228, 283, 284, 299 |
D08556 |
D09033 |
Voclosporin |
1件: 222 |
174 | Yersinia infection 9 genes, 3 drugs (DrugBank) and 22 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D09639 |
Losmapimod |
2件: 113, 222 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |