No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 7 genes, 12 drugs (DrugBank) and 42 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
4件: BRAF, FLT3, KIT, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: FLT3, KIT |
D10062 |
Cabozantinib |
1件: 34 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
2 | Adherens junction 3 genes, 4 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
3 | Adipocytokine signaling pathway 2 genes, 6 drugs (DrugBank) and 47 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
4 | Adrenergic signaling in cardiomyocytes 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: SCN5A |
D00354 |
Lamotrigine |
3件: 13, 34, 114 |
5 | African trypanosomiasis 4 genes, 3 drugs (DrugBank) and 19 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
6 | AGE-RAGE signaling pathway in diabetic complications 6 genes, 5 drugs (DrugBank) and 26 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
7 | Alanine, aspartate and glutamate metabolism 4 genes, 1 drug (DrugBank) and 14 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
8 | Alcoholism 5 genes, 7 drugs (DrugBank) and 8 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: NTRK2 |
D10062 |
Cabozantinib |
1件: 34 |
1件: SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
9 | Aldosterone synthesis and secretion 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
10 | Allograft rejection 2 genes, 3 drugs (DrugBank) and 19 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
11 | Alzheimer disease 2 genes, 3 drugs (DrugBank) and 19 diseases shown |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
12 | Amoebiasis 4 genes, 3 drugs (DrugBank) and 19 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
13 | Amphetamine addiction 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
14 | AMPK signaling pathway 2 genes, 5 drugs (DrugBank) and 50 diseases shown |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
15 | Amyotrophic lateral sclerosis (ALS) 1 gene, 3 drugs (DrugBank) and 19 diseases shown |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
16 | Antifolate resistance 5 genes, 4 drugs (DrugBank) and 42 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
17 | Antigen processing and presentation 1 gene, 3 drugs (DrugBank) and 19 diseases shown |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
18 | Apelin signaling pathway 4 genes, 7 drugs (DrugBank) and 37 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
19 | Apoptosis 4 genes, 7 drugs (DrugBank) and 20 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
20 | Arachidonic acid metabolism 2 genes, 4 drugs (DrugBank) and 20 diseases shown |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
21 | Asthma 2 genes, 3 drugs (DrugBank) and 19 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
22 | Autoimmune thyroid disease 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
23 | Autophagy - animal 4 genes, 7 drugs (DrugBank) and 37 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
24 | Autophagy - other 1 gene, 3 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
25 | Axon guidance 3 genes, 4 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
26 | B cell receptor signaling pathway 3 genes, 4 drugs (DrugBank) and 2 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
27 | Bacterial invasion of epithelial cells 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
28 | beta-Alanine metabolism 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: ABAT, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
29 | Bile secretion 1 gene, 2 drugs (DrugBank) and 23 diseases shown |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
30 | Bladder cancer 7 genes, 10 drugs (DrugBank) and 14 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
31 | Breast cancer 9 genes, 17 drugs (DrugBank) and 44 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
4件: BRAF, FLT4, KIT, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: FLT4 |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
2件: FLT4, KIT |
D10062 |
Cabozantinib |
1件: 34 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
32 | Butanoate metabolism 4 genes, 1 drug (DrugBank) and 14 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
33 | C-type lectin receptor signaling pathway 6 genes, 8 drugs (DrugBank) and 34 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
34 | Calcium signaling pathway 7 genes, 8 drugs (DrugBank) and 26 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: PDGFRB |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
35 | cAMP signaling pathway 4 genes, 5 drugs (DrugBank) and 2 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
36 | Cell cycle 1 gene, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
37 | Cellular senescence 6 genes, 9 drugs (DrugBank) and 43 diseases shown |
2件: IL1A, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
38 | Central carbon metabolism in cancer 12 genes, 14 drugs (DrugBank) and 44 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
4件: FLT3, KIT, MET, RET |
D10062 |
Cabozantinib |
1件: 34 |
5件: FLT3, KIT, PDGFRA, PDGFRB, RET |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
5件: FLT3, KIT, PDGFRB, RAF1, RET |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
39 | cGMP-PKG signaling pathway 6 genes, 5 drugs (DrugBank) and 12 diseases shown |
3件: ADRA2A, ADRA2B, ADRA2C |
D00514 |
Dexmedetomidine |
11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
40 | Chagas disease (American trypanosomiasis) 5 genes, 3 drugs (DrugBank) and 19 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
41 | Chemical carcinogenesis 1 gene, 4 drugs (DrugBank) and 20 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
42 | Chemokine signaling pathway 4 genes, 6 drugs (DrugBank) and 11 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: CCL2 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
43 | Choline metabolism in cancer 7 genes, 13 drugs (DrugBank) and 44 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
44 | Cholinergic synapse 1 gene, 3 drugs (DrugBank) and 1 disease shown |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
45 | Chronic myeloid leukemia 5 genes, 7 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
46 | Circadian entrainment 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
47 | Cocaine addiction 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
48 | Colorectal cancer 6 genes, 11 drugs (DrugBank) and 39 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
49 | Cortisol synthesis and secretion 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
50 | Cushing syndrome 7 genes, 9 drugs (DrugBank) and 18 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
51 | Cytokine-cytokine receptor interaction 10 genes, 6 drugs (DrugBank) and 35 diseases shown |
6件: CCL2, IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CSF1 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
52 | Cytosolic DNA-sensing pathway 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
53 | Dilated cardiomyopathy (DCM) 1 gene, 3 drugs (DrugBank) and 19 diseases shown |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
54 | Dopaminergic synapse 2 genes, 2 drugs (DrugBank) and 8 diseases shown |
1件: SCN1A |
D00354 |
Lamotrigine |
3件: 13, 34, 114 |
1件: SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
55 | EGFR tyrosine kinase inhibitor resistance 14 genes, 21 drugs (DrugBank) and 51 diseases shown |
3件: AXL, KDR, MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
4件: BRAF, KDR, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
3件: KDR, PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
56 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 1 drug (DrugBank) and 15 diseases shown |
1件: VDR |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
57 | Endocrine resistance 7 genes, 11 drugs (DrugBank) and 39 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
58 | Endocytosis 2 genes, 6 drugs (DrugBank) and 16 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
59 | Endometrial cancer 6 genes, 8 drugs (DrugBank) and 7 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
60 | Epithelial cell signaling in Helicobacter pylori infection 2 genes, 4 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
61 | Epstein-Barr virus infection 4 genes, 4 drugs (DrugBank) and 20 diseases shown |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
62 | ErbB signaling pathway 8 genes, 13 drugs (DrugBank) and 44 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
63 | Estrogen signaling pathway 4 genes, 7 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
64 | Fc epsilon RI signaling pathway 4 genes, 7 drugs (DrugBank) and 20 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
65 | Fc gamma R-mediated phagocytosis 2 genes, 4 drugs (DrugBank) and 2 diseases shown |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
66 | Fluid shear stress and atherosclerosis 6 genes, 10 drugs (DrugBank) and 26 diseases shown |
4件: CCL2, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: KDR |
D03218 |
Axitinib |
1件: 34 |
D10062 |
Cabozantinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
67 | Focal adhesion 12 genes, 16 drugs (DrugBank) and 20 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
5件: BRAF, FLT4, KDR, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
3件: FLT1, FLT4, KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
4件: FLT1, FLT4, KDR, MET |
D10062 |
Cabozantinib |
1件: 34 |
5件: FLT1, FLT4, KDR, PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
68 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
69 | FoxO signaling pathway 7 genes, 10 drugs (DrugBank) and 17 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
70 | GABAergic synapse 19 genes, 2 drugs (DrugBank) and 21 diseases shown |
3件: ABAT, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
71 | Gap junction 15 genes, 12 drugs (DrugBank) and 18 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D01068 |
Vinblastine |
1件: 34 |
D08675 |
D02197 |
Vincristine |
4件: 26, 34, 61, 331 |
D08679 |
72 | Gastric cancer 8 genes, 12 drugs (DrugBank) and 39 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
73 | Glioma 8 genes, 14 drugs (DrugBank) and 44 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
74 | GnRH secretion 6 genes, 5 drugs (DrugBank) and 15 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
75 | GnRH signaling pathway 4 genes, 7 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
76 | Graft-versus-host disease 4 genes, 3 drugs (DrugBank) and 19 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
77 | Growth hormone synthesis, secretion and action 4 genes, 7 drugs (DrugBank) and 37 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
78 | Hematopoietic cell lineage 8 genes, 9 drugs (DrugBank) and 40 diseases shown |
3件: CSF1, FLT3, KIT |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
2件: FLT3, KIT |
D10062 |
Cabozantinib |
1件: 34 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: KIT |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
79 | Hepatitis B 7 genes, 9 drugs (DrugBank) and 21 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: IFNAR1 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
80 | Hepatitis C 8 genes, 12 drugs (DrugBank) and 24 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
81 | Hepatocellular carcinoma 7 genes, 12 drugs (DrugBank) and 39 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
82 | Herpes simplex virus 1 infection 7 genes, 7 drugs (DrugBank) and 48 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
83 | HIF-1 signaling pathway 9 genes, 17 drugs (DrugBank) and 48 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: FLT1 |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: FLT1, TEK |
D10062 |
Cabozantinib |
1件: 34 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
84 | Human cytomegalovirus infection 12 genes, 22 drugs (DrugBank) and 62 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
85 | Human immunodeficiency virus 1 infection 5 genes, 10 drugs (DrugBank) and 47 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
86 | Human papillomavirus infection 11 genes, 22 drugs (DrugBank) and 62 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
87 | Human T-cell leukemia virus 1 infection 4 genes, 6 drugs (DrugBank) and 19 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
88 | Hypertrophic cardiomyopathy (HCM) 2 genes, 3 drugs (DrugBank) and 19 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
89 | IL-17 signaling pathway 5 genes, 7 drugs (DrugBank) and 34 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
90 | Inflammatory bowel disease (IBD) 5 genes, 3 drugs (DrugBank) and 19 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
91 | Inflammatory mediator regulation of TRP channels 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL1B |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
92 | Influenza A 11 genes, 9 drugs (DrugBank) and 21 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TLR7 |
D02500 |
Imiquimod |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
93 | Insulin resistance 3 genes, 6 drugs (DrugBank) and 47 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
94 | Insulin signaling pathway 5 genes, 8 drugs (DrugBank) and 37 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
95 | Intestinal immune network for IgA production 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
96 | JAK-STAT signaling pathway 10 genes, 14 drugs (DrugBank) and 58 diseases shown |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
97 | Kaposi sarcoma-associated herpesvirus infection 9 genes, 16 drugs (DrugBank) and 55 diseases shown |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
98 | Legionellosis 3 genes, 3 drugs (DrugBank) and 19 diseases shown |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
99 | Leishmaniasis 5 genes, 7 drugs (DrugBank) and 34 diseases shown |
4件: IL10, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
100 | Long-term depression 4 genes, 5 drugs (DrugBank) and 2 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
101 | Long-term potentiation 4 genes, 5 drugs (DrugBank) and 2 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
102 | Longevity regulating pathway 1 gene, 3 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
103 | Longevity regulating pathway - multiple species 1 gene, 3 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
104 | Malaria 6 genes, 4 drugs (DrugBank) and 19 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
105 | MAPK signaling pathway 24 genes, 20 drugs (DrugBank) and 40 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
7件: BRAF, FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
8件: CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
8件: FLT1, FLT3, FLT4, KDR, KIT, MET, NTRK2, TEK |
D10062 |
Cabozantinib |
1件: 34 |
3件: FLT1, FLT4, KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
106 | Measles 6 genes, 4 drugs (DrugBank) and 14 diseases shown |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TLR7 |
D02500 |
Imiquimod |
1件: 34 |
107 | Melanogenesis 4 genes, 8 drugs (DrugBank) and 13 diseases shown |
1件: KIT |
D10062 |
Cabozantinib |
1件: 34 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: KIT, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
108 | Melanoma 8 genes, 12 drugs (DrugBank) and 16 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
109 | Metabolic pathways 9 genes, 8 drugs (DrugBank) and 64 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
110 | MicroRNAs in cancer 12 genes, 20 drugs (DrugBank) and 54 diseases shown |
2件: ABL1, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: ABL1, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
2件: PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
111 | Mineral absorption 1 gene, 1 drug (DrugBank) and 15 diseases shown |
1件: VDR |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
112 | Morphine addiction 16 genes, 1 drug (DrugBank) and 8 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
113 | mTOR signaling pathway 6 genes, 11 drugs (DrugBank) and 47 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
114 | Natural killer cell mediated cytotoxicity 7 genes, 9 drugs (DrugBank) and 21 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
115 | Necroptosis 5 genes, 4 drugs (DrugBank) and 20 diseases shown |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
116 | Neuroactive ligand-receptor interaction 19 genes, 2 drugs (DrugBank) and 16 diseases shown |
3件: ADRA2A, ADRA2B, ADRA2C |
D00514 |
Dexmedetomidine |
11件: 2, 4, 6, 21, 34, 70, 113, 212, 215, 226, 280 |
D01205 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
117 | Neurotrophin signaling pathway 6 genes, 8 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: NTRK2 |
D10062 |
Cabozantinib |
1件: 34 |
118 | NF-kappa B signaling pathway 3 genes, 7 drugs (DrugBank) and 34 diseases shown |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
119 | Nicotine addiction 16 genes, 1 drug (DrugBank) and 8 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
120 | NOD-like receptor signaling pathway 6 genes, 4 drugs (DrugBank) and 20 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
121 | Non-alcoholic fatty liver disease (NAFLD) 4 genes, 3 drugs (DrugBank) and 19 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
122 | Non-small cell lung cancer 6 genes, 8 drugs (DrugBank) and 7 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
123 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
124 | Oocyte meiosis 1 gene, 3 drugs (DrugBank) and 1 disease shown |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
125 | Osteoclast differentiation 7 genes, 8 drugs (DrugBank) and 20 diseases shown |
1件: CSF1 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
126 | Ovarian steroidogenesis 1 gene, 4 drugs (DrugBank) and 20 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
127 | Oxytocin signaling pathway 5 genes, 11 drugs (DrugBank) and 23 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
128 | Pancreatic cancer 7 genes, 13 drugs (DrugBank) and 43 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
129 | Parathyroid hormone synthesis, secretion and action 5 genes, 9 drugs (DrugBank) and 21 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: VDR |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
130 | Parkinson disease 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
131 | Pathogenic Escherichia coli infection 13 genes, 7 drugs (DrugBank) and 28 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D01068 |
Vinblastine |
1件: 34 |
D08675 |
D02197 |
Vincristine |
4件: 26, 34, 61, 331 |
D08679 |
132 | Pathways in cancer 21 genes, 27 drugs (DrugBank) and 66 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
7件: BRAF, FLT3, FLT4, KIT, PDGFRB, RAF1, RET |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
5件: FLT3, FLT4, KIT, MET, RET |
D10062 |
Cabozantinib |
1件: 34 |
6件: FLT3, FLT4, KIT, PDGFRA, PDGFRB, RET |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: FLT4 |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
133 | PD-L1 expression and PD-1 checkpoint pathway in cancer 5 genes, 10 drugs (DrugBank) and 39 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
134 | Pertussis 5 genes, 3 drugs (DrugBank) and 19 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
135 | Phagosome 9 genes, 2 drugs (DrugBank) and 4 diseases shown |
9件: TUBB, TUBB1, TUBB2A, TUBB2B, TUBB3, TUBB4A, TUBB4B, TUBB6, TUBB8 |
D01068 |
Vinblastine |
1件: 34 |
D08675 |
D02197 |
Vincristine |
4件: 26, 34, 61, 331 |
D08679 |
136 | Phospholipase D signaling pathway 8 genes, 14 drugs (DrugBank) and 44 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: KIT |
D10062 |
Cabozantinib |
1件: 34 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
3件: KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
137 | PI3K-Akt signaling pathway 22 genes, 22 drugs (DrugBank) and 60 diseases shown |
8件: CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: CSF3R |
D03235 |
Filgrastim |
28件: 2, 6, 13, 16, 25, 26, 28, 34, 35, 36, 40, 41, 42, 45, 46, 49, 51, 60, 62, 65, 85, 96, 113, 164, 283, 284, 285, 331 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
8件: FLT1, FLT3, FLT4, KDR, KIT, MET, NTRK2, TEK |
D10062 |
Cabozantinib |
1件: 34 |
3件: FLT1, FLT4, KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
138 | Platelet activation 1 gene, 3 drugs (DrugBank) and 16 diseases shown |
1件: PTGS1 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
139 | Platinum drug resistance 3 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: TOP2A, TOP2B |
D03899 |
Doxorubicin |
6件: 26, 28, 34, 61, 63, 331 |
D00125 |
Etoposide |
11件: 11, 13, 14, 26, 28, 34, 60, 65, 85, 164, 331 |
D04107 |
140 | Prion diseases 5 genes, 5 drugs (DrugBank) and 13 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
141 | Progesterone-mediated oocyte maturation 3 genes, 5 drugs (DrugBank) and 2 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
142 | Prolactin signaling pathway 3 genes, 4 drugs (DrugBank) and 2 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
143 | Propanoate metabolism 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: ABAT |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
144 | Prostate cancer 9 genes, 14 drugs (DrugBank) and 44 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
145 | Proteoglycans in cancer 11 genes, 20 drugs (DrugBank) and 52 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
3件: BRAF, KDR, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: KDR, MET |
D10062 |
Cabozantinib |
1件: 34 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
146 | Rap1 signaling pathway 15 genes, 16 drugs (DrugBank) and 20 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
6件: BRAF, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
7件: CSF1, FLT1, FLT4, KDR, KIT, PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
3件: FLT1, FLT4, KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
6件: FLT1, FLT4, KDR, KIT, MET, TEK |
D10062 |
Cabozantinib |
1件: 34 |
2件: KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
147 | Ras signaling pathway 17 genes, 15 drugs (DrugBank) and 20 diseases shown |
3件: ABL1, KIT, PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
8件: CSF1, FLT1, FLT3, FLT4, KDR, KIT, PDGFRA, PDGFRB |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
8件: FLT1, FLT3, FLT4, KDR, KIT, MET, NTRK2, TEK |
D10062 |
Cabozantinib |
1件: 34 |
3件: FLT1, FLT4, KDR |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
6件: FLT3, FLT4, KDR, KIT, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
148 | Regulation of actin cytoskeleton 7 genes, 11 drugs (DrugBank) and 16 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
3件: BRAF, PDGFRB, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: PDGFRA |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
149 | Regulation of lipolysis in adipocytes 2 genes, 4 drugs (DrugBank) and 20 diseases shown |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
150 | Relaxin signaling pathway 5 genes, 9 drugs (DrugBank) and 14 diseases shown |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
151 | Renal cell carcinoma 6 genes, 8 drugs (DrugBank) and 11 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
152 | Retrograde endocannabinoid signaling 17 genes, 5 drugs (DrugBank) and 24 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
153 | Rheumatoid arthritis 9 genes, 9 drugs (DrugBank) and 26 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: CSF1, FLT1 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
1件: FLT1 |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
2件: FLT1, TEK |
D10062 |
Cabozantinib |
1件: 34 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
154 | RIG-I-like receptor signaling pathway 1 gene, 3 drugs (DrugBank) and 19 diseases shown |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
155 | Salmonella infection 3 genes, 2 drugs (DrugBank) and 13 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
156 | Serotonergic synapse 8 genes, 10 drugs (DrugBank) and 24 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
3件: GABRB1, GABRB2, GABRB3 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
2件: PTGS1, PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: PTGS2 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
157 | Shigellosis 5 genes, 11 drugs (DrugBank) and 53 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: EGFR |
D03455 |
Cetuximab |
5件: 34, 51, 86, 89, 331 |
D11251 |
Icotinib |
1件: 34 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
158 | Signaling pathways regulating pluripotency of stem cells 3 genes, 4 drugs (DrugBank) and 2 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
159 | Small cell lung cancer 1 gene, 4 drugs (DrugBank) and 20 diseases shown |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
160 | Sphingolipid signaling pathway 4 genes, 7 drugs (DrugBank) and 20 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
161 | Staphylococcus aureus infection 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
162 | Synaptic vesicle cycle 2 genes, 1 drug (DrugBank) and 7 diseases shown |
2件: SLC6A2, SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
163 | Systemic lupus erythematosus 2 genes, 3 drugs (DrugBank) and 19 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
164 | T cell receptor signaling pathway 5 genes, 7 drugs (DrugBank) and 20 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
165 | Taste transduction 9 genes, 2 drugs (DrugBank) and 10 diseases shown |
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
3件: SCN2A, SCN3A, SCN9A |
D00354 |
Lamotrigine |
3件: 13, 34, 114 |
166 | Taurine and hypotaurine metabolism 2 genes, 1 drug (DrugBank) and 14 diseases shown |
2件: GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
167 | Terpenoid backbone biosynthesis 3 genes, 3 drugs (DrugBank) and 23 diseases shown |
2件: FNTA, FNTB |
D03720 |
Tipifarnib |
1件: 34 |
1件: HMGCR |
D00359 |
Lovastatin |
10件: 6, 34, 46, 79, 156, 160, 195, 206, 263, 310 |
D00434 |
Simvastatin |
19件: 6, 13, 15, 34, 46, 49, 51, 66, 79, 86, 89, 94, 158, 162, 195, 265, 298, 299, 310 |
168 | TGF-beta signaling pathway 1 gene, 3 drugs (DrugBank) and 19 diseases shown |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
169 | Th17 cell differentiation 3 genes, 5 drugs (DrugBank) and 43 diseases shown |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
170 | Thermogenesis 1 gene, 3 drugs (DrugBank) and 37 diseases shown |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
171 | Thyroid cancer 4 genes, 7 drugs (DrugBank) and 3 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RET |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: RET |
D10062 |
Cabozantinib |
1件: 34 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
172 | Thyroid hormone signaling pathway 4 genes, 7 drugs (DrugBank) and 37 diseases shown |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
173 | Tight junction 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
174 | TNF signaling pathway 7 genes, 11 drugs (DrugBank) and 34 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CSF1 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: MAP2K1 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
175 | Toll-like receptor signaling pathway 8 genes, 8 drugs (DrugBank) and 20 diseases shown |
2件: IFNAR1, IFNAR2 |
D02745 |
Interferon alfa-2b |
3件: 25, 34, 227 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TLR7 |
D02500 |
Imiquimod |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
176 | Toxoplasmosis 2 genes, 3 drugs (DrugBank) and 19 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
177 | Transcriptional misregulation in cancer 4 genes, 7 drugs (DrugBank) and 14 diseases shown |
1件: FLT1 |
D03218 |
Axitinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
2件: FLT1, FLT3 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
3件: FLT1, FLT3, MET |
D10062 |
Cabozantinib |
1件: 34 |
1件: FLT3 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
178 | Tuberculosis 7 genes, 5 drugs (DrugBank) and 30 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
1件: VDR |
D00188 |
Cholecalciferol |
15件: 6, 13, 19, 20, 34, 46, 49, 53, 60, 65, 96, 97, 228, 298, 299 |
179 | Type I diabetes mellitus 5 genes, 4 drugs (DrugBank) and 29 diseases shown |
2件: GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
180 | Type II diabetes mellitus 3 genes, 7 drugs (DrugBank) and 53 diseases shown |
1件: CACNA1G |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: MTOR |
D02714 |
Everolimus |
9件: 34, 67, 89, 96, 137, 157, 158, 228, 277 |
D00753 |
Sirolimus |
36件: 2, 13, 15, 17, 34, 35, 36, 46, 49, 51, 60, 61, 62, 63, 65, 66, 67, 85, 86, 89, 96, 98, 137, 157, 158, 192, 222, 256, 277, 278, 279, 280, 281, 283, 285, 331 |
D06068 |
Temsirolimus |
4件: 13, 34, 89, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
181 | Valine, leucine and isoleucine degradation 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: ABAT |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
182 | Vascular smooth muscle contraction 4 genes, 5 drugs (DrugBank) and 2 diseases shown |
1件: BRAF |
D10064 |
Dabrafenib |
1件: 34 |
2件: BRAF, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
183 | VEGF signaling pathway 6 genes, 14 drugs (DrugBank) and 28 diseases shown |
1件: KDR |
D03218 |
Axitinib |
1件: 34 |
D10062 |
Cabozantinib |
1件: 34 |
D08881 |
Cediranib |
1件: 34 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: KDR, RAF1 |
D06272 |
Sorafenib |
2件: 34, 86 |
D08524 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: PTGS2 |
D00217 |
Acetaminophen |
13件: 3, 6, 13, 34, 35, 46, 49, 51, 70, 86, 231, 256, 271 |
D00109 |
Acetylsalicylic acid |
10件: 13, 22, 34, 46, 49, 51, 86, 113, 158, 231 |
D00567 |
Celecoxib |
9件: 2, 3, 34, 46, 70, 89, 96, 161, 271 |
D00903 |
Diclofenac |
4件: 13, 34, 46, 271 |
D00904 |
D07816 |
1件: VEGFA |
D06409 |
Bevacizumab |
9件: 13, 34, 85, 86, 87, 89, 227, 280, 331 |
D05697 |
Ranibizumab |
4件: 34, 166, 227, 301 |
184 | Viral myocarditis 1 gene, 2 drugs (DrugBank) and 13 diseases shown |
1件: ABL1 |
D01441 |
Imatinib |
11件: 13, 28, 34, 35, 46, 51, 85, 86, 87, 89, 162 |
D08066 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
185 | Viral protein interaction with cytokine and cytokine receptor 5 genes, 4 drugs (DrugBank) and 19 diseases shown |
4件: CCL2, IL10, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CSF1 |
D06402 |
Sunitinib |
2件: 28, 34 |
D08552 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |
186 | Yersinia infection 7 genes, 6 drugs (DrugBank) and 19 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL6, TNF |
D08976 |
Pomalidomide |
6件: 28, 34, 51, 85, 227, 331 |
2件: MAP2K1, MAP2K2 |
D10604 |
Binimetinib |
1件: 34 |
D09666 |
Selumetinib |
1件: 34 |
D10175 |
Trametinib |
1件: 34 |
1件: TNF |
D04687 |
Lenalidomide |
8件: 16, 26, 28, 34, 49, 96, 284, 300 |