No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PML, RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
2 | Adherens junction 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
3 | Adipocytokine signaling pathway 5 genes, 2 drugs (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
4 | Adrenergic signaling in cardiomyocytes 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
5 | AGE-RAGE signaling pathway in diabetic complications 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
6 | Alcoholism 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
7 | Aldosterone synthesis and secretion 3 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: CYP11B2 |
D11061 |
Osilodrostat |
1件: 75 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
8 | Aldosterone-regulated sodium reabsorption 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: NR3C2 |
D01115 |
Eplerenone |
3件: 75, 113, 215 |
9 | AMPK signaling pathway 3 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
10 | Apelin signaling pathway 3 genes, 2 drugs (DrugBank) and 22 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
11 | Autophagy - animal 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
12 | Bile secretion 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: RXRA |
D03106 |
Bexarotene |
2件: 13, 75 |
13 | Bladder cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
14 | Breast cancer 3 genes, 3 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: PGR |
D00585 |
Mifepristone |
1件: 75 |
15 | Calcium signaling pathway 3 genes, 3 drugs (DrugBank) and 8 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
16 | cAMP signaling pathway 6 genes, 5 drugs (DrugBank) and 19 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
1件: GLP1R |
D06404 |
Liraglutide |
3件: 6, 75, 193 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
3件: SSTR1, SSTR2, SSTR5 |
D10147 |
Pasireotide |
3件: 67, 74, 75 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
17 | Central carbon metabolism in cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
18 | cGMP-PKG signaling pathway 2 genes, 2 drugs (DrugBank) and 11 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: PDE5A |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
19 | Choline metabolism in cancer 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
20 | Circadian rhythm 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
21 | Cocaine addiction 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
22 | Colorectal cancer 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
23 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: F8 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
24 | Cortisol synthesis and secretion 4 genes, 4 drugs (DrugBank) and 16 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: CYP11B1 |
D00410 |
Metyrapone |
2件: 75, 193 |
D05019 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
25 | Cushing syndrome 7 genes, 8 drugs (DrugBank) and 18 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
2件: CRHR1, CRHR2 |
D03905 |
Corticorelin |
2件: 75, 78 |
D03592 |
Corticorelin ovine triflutate |
1件: 75 |
1件: CYP11B1 |
D00410 |
Metyrapone |
2件: 75, 193 |
D05019 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
26 | Cytokine-cytokine receptor interaction 2 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: PRL |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
27 | Dopaminergic synapse 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
28 | EGFR tyrosine kinase inhibitor resistance 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
29 | Endocrine resistance 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
30 | Endocytosis 2 genes, 3 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
31 | Endometrial cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
32 | Epithelial cell signaling in Helicobacter pylori infection 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
33 | ErbB signaling pathway 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
34 | Estrogen signaling pathway 3 genes, 4 drugs (DrugBank) and 7 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: PGR |
D00585 |
Mifepristone |
1件: 75 |
1件: RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
35 | Fluid shear stress and atherosclerosis 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
36 | Focal adhesion 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
37 | FoxO signaling pathway 3 genes, 3 drugs (DrugBank) and 19 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
38 | Gap junction 2 genes, 3 drugs (DrugBank) and 4 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
39 | Gastric acid secretion 1 gene, 2 drugs (DrugBank) and 9 diseases shown |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
D10147 |
Pasireotide |
3件: 67, 74, 75 |
40 | Gastric cancer 6 genes, 4 drugs (DrugBank) and 8 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
41 | Glioma 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
42 | Glucagon signaling pathway 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
43 | GnRH signaling pathway 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
44 | Growth hormone synthesis, secretion and action 5 genes, 3 drugs (DrugBank) and 23 diseases shown |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
4件: SSTR1, SSTR2, SSTR3, SSTR5 |
D10147 |
Pasireotide |
3件: 67, 74, 75 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
45 | Hepatitis C 2 genes, 3 drugs (DrugBank) and 4 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: RXRA |
D03106 |
Bexarotene |
2件: 13, 75 |
46 | Hepatocellular carcinoma 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
47 | Herpes simplex virus 1 infection 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
48 | HIF-1 signaling pathway 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
49 | Human cytomegalovirus infection 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
50 | Human papillomavirus infection 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
51 | Huntington disease 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
52 | Hypertrophic cardiomyopathy (HCM) 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
53 | Influenza A 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
54 | Insulin resistance 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
55 | Insulin secretion 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: GLP1R |
D06404 |
Liraglutide |
3件: 6, 75, 193 |
56 | Insulin signaling pathway 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
57 | JAK-STAT signaling pathway 3 genes, 4 drugs (DrugBank) and 20 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: PRL |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
58 | Long-term depression 1 gene, 2 drugs (DrugBank) and 2 diseases shown |
1件: CRHR1 |
D03905 |
Corticorelin |
2件: 75, 78 |
D03592 |
Corticorelin ovine triflutate |
1件: 75 |
59 | Longevity regulating pathway 3 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
60 | Longevity regulating pathway - multiple species 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
61 | MAPK signaling pathway 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
62 | Melanoma 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
63 | Metabolic pathways 4 genes, 4 drugs (DrugBank) and 9 diseases shown |
1件: CYP11B1 |
D00410 |
Metyrapone |
2件: 75, 193 |
D05019 |
1件: CYP11B2 |
D11061 |
Osilodrostat |
1件: 75 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
1件: PDE5A |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
64 | MicroRNAs in cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
65 | mTOR signaling pathway 2 genes, 1 drug (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
66 | Neuroactive ligand-receptor interaction 14 genes, 16 drugs (DrugBank) and 66 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: AVPR2 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
2件: CRHR1, CRHR2 |
D03905 |
Corticorelin |
2件: 75, 78 |
D03592 |
Corticorelin ovine triflutate |
1件: 75 |
2件: DRD2, PRL |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
1件: GLP1R |
D06404 |
Liraglutide |
3件: 6, 75, 193 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
1件: NR3C1 |
D00292 |
Dexamethasone |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D00088 |
Hydrocortisone |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
D00165 |
Hydrocortisone acetate |
8件: 6, 53, 75, 78, 81, 83, 97, 299 |
D00585 |
Mifepristone |
1件: 75 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D11336 |
Relacorilant |
1件: 75 |
4件: SSTR1, SSTR2, SSTR3, SSTR5 |
D10147 |
Pasireotide |
3件: 67, 74, 75 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
67 | Non-alcoholic fatty liver disease (NAFLD) 3 genes, 2 drugs (DrugBank) and 17 diseases shown |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: RXRA |
D03106 |
Bexarotene |
2件: 13, 75 |
68 | Non-small cell lung cancer 6 genes, 4 drugs (DrugBank) and 8 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
69 | Oocyte meiosis 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PGR |
D00585 |
Mifepristone |
1件: 75 |
70 | Osteoclast differentiation 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
71 | Ovarian steroidogenesis 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
72 | Oxytocin signaling pathway 3 genes, 3 drugs (DrugBank) and 19 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
73 | Pancreatic cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
74 | Parathyroid hormone synthesis, secretion and action 4 genes, 3 drugs (DrugBank) and 4 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
75 | Parkinson disease 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
76 | Pathways in cancer 10 genes, 6 drugs (DrugBank) and 16 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
3件: PML, RARA, RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
77 | PD-L1 expression and PD-1 checkpoint pathway in cancer 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
78 | Phospholipase D signaling pathway 3 genes, 4 drugs (DrugBank) and 13 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
1件: AVPR2 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
79 | PI3K-Akt signaling pathway 7 genes, 6 drugs (DrugBank) and 30 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
1件: GHR |
D02691 |
Somatotropin |
18件: 2, 3, 13, 19, 46, 74, 75, 78, 96, 113, 191, 193, 195, 236, 265, 274, 276, 299 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
1件: PRL |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
1件: RXRA |
D03106 |
Bexarotene |
2件: 13, 75 |
80 | Platinum drug resistance 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
81 | PPAR signaling pathway 4 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
82 | Progesterone-mediated oocyte maturation 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: PGR |
D00585 |
Mifepristone |
1件: 75 |
83 | Prolactin signaling pathway 2 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
1件: PRL |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
84 | Prostate cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
85 | Protein digestion and absorption 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: DPP4 |
D08516 |
Sitagliptin |
3件: 75, 233, 299 |
86 | Proteoglycans in cancer 2 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
2件: EGFR, ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
87 | Purine metabolism 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: PDE5A |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
88 | Rap1 signaling pathway 2 genes, 3 drugs (DrugBank) and 4 diseases shown |
1件: DRD2 |
D00987 |
Cabergoline |
3件: 6, 74, 75 |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
89 | Ras signaling pathway 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
90 | Regulation of actin cytoskeleton 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
91 | Relaxin signaling pathway 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
92 | Renin secretion 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
93 | Renin-angiotensin system 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
94 | Shigellosis 1 gene, 2 drugs (DrugBank) and 3 diseases shown |
1件: EGFR |
D01977 |
Gefitinib |
1件: 75 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
95 | Small cell lung cancer 4 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: RARB |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
96 | Steroid hormone biosynthesis 3 genes, 3 drugs (DrugBank) and 4 diseases shown |
1件: CYP11B1 |
D00410 |
Metyrapone |
2件: 75, 193 |
D05019 |
1件: CYP11B2 |
D11061 |
Osilodrostat |
1件: 75 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
97 | Th17 cell differentiation 4 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
98 | Thermogenesis 3 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
99 | Thyroid cancer 4 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
100 | Thyroid hormone signaling pathway 3 genes, 1 drug (DrugBank) and 2 diseases shown |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
101 | Tight junction 3 genes, 2 drugs (DrugBank) and 19 diseases shown |
1件: ERBB2 |
D04024 |
Lapatinib |
3件: 34, 74, 75 |
D08108 |
2件: PRKAA1, PRKAA2 |
D00944 |
Metformin |
17件: 6, 13, 46, 49, 67, 75, 77, 81, 86, 113, 158, 206, 225, 233, 265, 285, 299 |
D04966 |
102 | Transcriptional misregulation in cancer 6 genes, 3 drugs (DrugBank) and 10 diseases shown |
2件: PML, RARA |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
1件: PPARG |
D00596 |
Rosiglitazone |
5件: 46, 75, 97, 222, 265 |
D08491 |
3件: RXRA, RXRB, RXRG |
D03106 |
Bexarotene |
2件: 13, 75 |
103 | Ubiquitin mediated proteolysis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PML |
D00094 |
Tretinoin |
5件: 2, 63, 75, 94, 231 |
104 | Vascular smooth muscle contraction 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AGTR1 |
D00400 |
Valsartan |
6件: 57, 58, 66, 75, 218, 222 |
105 | Vasopressin-regulated water reabsorption 1 gene, 1 drug (DrugBank) and 6 diseases shown |
1件: AVPR2 |
D00291 |
Desmopressin |
6件: 6, 64, 72, 75, 225, 288 |
D02235 |