No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Acute myeloid leukemia 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KIT |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
2 | Adipocytokine signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
3 | Adrenergic signaling in cardiomyocytes 12 genes, 4 drugs (DrugBank) and 4 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
1件: SCN5A |
D00642 |
Quinidine |
3件: 2, 8, 13 |
D00643 |
D02272 |
D08458 |
4 | AGE-RAGE signaling pathway in diabetic complications 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
5 | Alanine, aspartate and glutamate metabolism 4 genes, 1 drug (DrugBank) and 14 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
6 | Alcoholism 8 genes, 12 drugs (DrugBank) and 18 diseases shown |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
D09953 |
Pridopidine |
2件: 6, 8 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
7 | Aldosterone synthesis and secretion 7 genes, 2 drugs (DrugBank) and 15 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
8 | Aldosterone-regulated sodium reabsorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
9 | Alzheimer disease 5 genes, 5 drugs (DrugBank) and 16 diseases shown |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
10 | Amphetamine addiction 11 genes, 8 drugs (DrugBank) and 16 diseases shown |
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
11 | AMPK signaling pathway 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: ADRA1A |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
12 | Amyotrophic lateral sclerosis (ALS) 11 genes, 6 drugs (DrugBank) and 16 diseases shown |
7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
13 | Axon guidance 2 genes, 2 drugs (DrugBank) and 6 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: SEMA4D |
D11469 |
Pepinemab |
2件: 8, 13 |
14 | beta-Alanine metabolism 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: ABAT, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
15 | Bile secretion 5 genes, 2 drugs (DrugBank) and 13 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: NR1H4 |
D00734 |
Ursodeoxycholic acid |
12件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 |
16 | Breast cancer 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KIT |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
17 | Butanoate metabolism 4 genes, 1 drug (DrugBank) and 14 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
18 | C-type lectin receptor signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
19 | Calcium signaling pathway 17 genes, 9 drugs (DrugBank) and 30 diseases shown |
8件: ADRA1A, ADRA1B, ADRA1D, HRH1, HTR2A, HTR2B, HTR2C, HTR6 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
4件: GRIN1, GRIN2A, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
1件: HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
20 | cAMP signaling pathway 20 genes, 12 drugs (DrugBank) and 22 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D09953 |
Pridopidine |
2件: 6, 8 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
2件: DRD2, HTR6 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D01783 |
Rolipram |
2件: 8, 13 |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
21 | Carbohydrate digestion and absorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
22 | Cardiac muscle contraction 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
23 | Cell cycle 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
24 | Cellular senescence 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
25 | Central carbon metabolism in cancer 3 genes, 1 drug (DrugBank) and 5 diseases shown |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
26 | cGMP-PKG signaling pathway 10 genes, 3 drugs (DrugBank) and 3 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
3件: ADRA2A, ADRA2B, ADRA2C |
D08482 |
Rilmenidine |
1件: 8 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
27 | Chagas disease (American trypanosomiasis) 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
28 | Choline metabolism in cancer 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
29 | Cholinergic synapse 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: ACHE |
D09917 |
Latrepirdine |
1件: 8 |
30 | Chronic myeloid leukemia 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
31 | Circadian entrainment 14 genes, 7 drugs (DrugBank) and 26 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
2件: MTNR1A, MTNR1B |
D02689 |
Ramelteon |
3件: 6, 8, 46 |
32 | Cocaine addiction 9 genes, 12 drugs (DrugBank) and 18 diseases shown |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
D09953 |
Pridopidine |
2件: 6, 8 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
6件: GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
33 | Collecting duct acid secretion 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
34 | Cortisol synthesis and secretion 4 genes, 2 drugs (DrugBank) and 16 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
35 | Cushing syndrome 4 genes, 2 drugs (DrugBank) and 16 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
36 | Dopaminergic synapse 16 genes, 14 drugs (DrugBank) and 18 diseases shown |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D09953 |
Pridopidine |
2件: 6, 8 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
3件: DRD2, DRD3, DRD4 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
6件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN2A, GRIN2B |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
2件: GRIN2A, GRIN2B |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
1件: SCN1A |
D00642 |
Quinidine |
3件: 2, 8, 13 |
D00643 |
D02272 |
D08458 |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
37 | EGFR tyrosine kinase inhibitor resistance 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
38 | Endocrine and other factor-regulated calcium reabsorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
39 | Endocrine resistance 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
40 | Endocytosis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PDGFRA |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
41 | Epithelial cell signaling in Helicobacter pylori infection 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
42 | Epstein-Barr virus infection 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
43 | ErbB signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
44 | Fc epsilon RI signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
45 | Fluid shear stress and atherosclerosis 5 genes, 2 drugs (DrugBank) and 10 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
46 | Focal adhesion 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
47 | FoxO signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
48 | GABAergic synapse 19 genes, 2 drugs (DrugBank) and 14 diseases shown |
3件: ABAT, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00225 |
Alprazolam |
1件: 8 |
49 | Gap junction 6 genes, 5 drugs (DrugBank) and 10 diseases shown |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D09953 |
Pridopidine |
2件: 6, 8 |
2件: DRD2, HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
4件: DRD2, HTR2A, HTR2B, HTR2C |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
50 | Gastric acid secretion 6 genes, 2 drugs (DrugBank) and 15 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
51 | Glioma 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
52 | Glucagon signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
53 | Glutamatergic synapse 14 genes, 5 drugs (DrugBank) and 16 diseases shown |
14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
54 | Glycerophospholipid metabolism 1 gene, 1 drug (DrugBank) and 1 disease shown |
1件: ACHE |
D09917 |
Latrepirdine |
1件: 8 |
55 | GnRH secretion 3 genes, 1 drug (DrugBank) and 14 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
56 | GnRH signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
57 | Growth hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
58 | Hematopoietic cell lineage 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KIT |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
59 | Hepatitis B 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
60 | Hepatitis C 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
61 | Hepatocellular carcinoma 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
62 | Human cytomegalovirus infection 5 genes, 2 drugs (DrugBank) and 5 diseases shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
1件: PDGFRA |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
63 | Human immunodeficiency virus 1 infection 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
64 | Human papillomavirus infection 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
65 | Huntington disease 2 genes, 5 drugs (DrugBank) and 16 diseases shown |
2件: GRIN1, GRIN2B |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
66 | IL-17 signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
67 | Inflammatory mediator regulation of TRP channels 8 genes, 3 drugs (DrugBank) and 6 diseases shown |
4件: HRH1, HTR2A, HTR2B, HTR2C |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
1件: HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
68 | Insulin resistance 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
69 | Insulin secretion 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
70 | JAK-STAT signaling pathway 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
71 | Kaposi sarcoma-associated herpesvirus infection 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
72 | Leishmaniasis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
73 | Leukocyte transendothelial migration 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
74 | Long-term depression 3 genes, 1 drug (DrugBank) and 7 diseases shown |
3件: GRIA1, GRIA2, GRIA3 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
75 | Long-term potentiation 7 genes, 5 drugs (DrugBank) and 16 diseases shown |
7件: GRIA1, GRIA2, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
76 | MAPK signaling pathway 10 genes, 3 drugs (DrugBank) and 17 diseases shown |
3件: CACNA1G, CACNA1H, CACNA1I |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
77 | Melanogenesis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: KIT |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
78 | Melanoma 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
79 | Metabolic pathways 13 genes, 5 drugs (DrugBank) and 33 diseases shown |
4件: ABAT, ALDH5A1, GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
2件: NQO1, VKORC1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D01783 |
Rolipram |
2件: 8, 13 |
80 | MicroRNAs in cancer 3 genes, 1 drug (DrugBank) and 5 diseases shown |
3件: ABL1, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
81 | Mineral absorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
82 | Morphine addiction 20 genes, 2 drugs (DrugBank) and 2 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00225 |
Alprazolam |
1件: 8 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D01783 |
Rolipram |
2件: 8, 13 |
83 | Neuroactive ligand-receptor interaction 46 genes, 12 drugs (DrugBank) and 18 diseases shown |
11件: ADRA1A, ADRA1B, ADRA1D, DRD2, DRD3, DRD4, HRH1, HTR2A, HTR2B, HTR2C, HTR6 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
3件: ADRA2A, ADRA2B, ADRA2C |
D08482 |
Rilmenidine |
1件: 8 |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D09953 |
Pridopidine |
2件: 6, 8 |
2件: DRD2, HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00225 |
Alprazolam |
1件: 8 |
14件: GRIA1, GRIA2, GRIA3, GRIA4, GRIK1, GRIK2, GRIK3, GRIK4, GRIK5, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
2件: MTNR1A, MTNR1B |
D02689 |
Ramelteon |
3件: 6, 8, 46 |
84 | Neurotrophin signaling pathway 5 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
85 | Nicotine addiction 25 genes, 6 drugs (DrugBank) and 16 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00225 |
Alprazolam |
1件: 8 |
9件: GRIA1, GRIA2, GRIA3, GRIA4, GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
5件: GRIN1, GRIN2A, GRIN2B, GRIN2C, GRIN2D |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
86 | NOD-like receptor signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
87 | Non-alcoholic fatty liver disease (NAFLD) 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
88 | Oocyte meiosis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
89 | Osteoclast differentiation 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
90 | Ovarian steroidogenesis 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
91 | Oxidative phosphorylation 2 genes, 1 drug (DrugBank) and 15 diseases shown |
2件: ATP4A, ATP4B |
D00455 |
Omeprazole |
15件: 6, 8, 13, 46, 51, 85, 96, 97, 98, 225, 271, 282, 294, 298, 299 |
D01207 |
D05259 |
D05261 |
92 | Pancreatic secretion 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
93 | Parathyroid hormone synthesis, secretion and action 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D01783 |
Rolipram |
2件: 8, 13 |
94 | Parkinson disease 3 genes, 7 drugs (DrugBank) and 8 diseases shown |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
D09953 |
Pridopidine |
2件: 6, 8 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
95 | Pathogenic Escherichia coli infection 5 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
96 | Pathways in cancer 5 genes, 2 drugs (DrugBank) and 13 diseases shown |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
1件: NQO1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
97 | PD-L1 expression and PD-1 checkpoint pathway in cancer 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
98 | Pertussis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
99 | Phospholipase D signaling pathway 3 genes, 1 drug (DrugBank) and 5 diseases shown |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
100 | PI3K-Akt signaling pathway 3 genes, 1 drug (DrugBank) and 5 diseases shown |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
101 | Platelet activation 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
102 | PPAR signaling pathway 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: PPARA |
D00565 |
Fenofibrate |
5件: 8, 79, 93, 94, 265 |
103 | Progesterone-mediated oocyte maturation 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
104 | Prolactin signaling pathway 5 genes, 2 drugs (DrugBank) and 3 diseases shown |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
105 | Propanoate metabolism 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: ABAT |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
106 | Prostate cancer 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
107 | Protein digestion and absorption 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
108 | Proteoglycans in cancer 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
109 | Proximal tubule bicarbonate reclamation 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
110 | Purine metabolism 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D01783 |
Rolipram |
2件: 8, 13 |
111 | Rap1 signaling pathway 11 genes, 11 drugs (DrugBank) and 21 diseases shown |
1件: DRD2 |
D00136 |
Haloperidol |
1件: 8 |
D01898 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
D09953 |
Pridopidine |
2件: 6, 8 |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
3件: GRIN1, GRIN2A, GRIN2B |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
3件: KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
112 | Ras signaling pathway 7 genes, 6 drugs (DrugBank) and 19 diseases shown |
4件: ABL1, KIT, PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
3件: GRIN1, GRIN2A, GRIN2B |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
113 | Regulation of actin cytoskeleton 2 genes, 1 drug (DrugBank) and 5 diseases shown |
2件: PDGFRA, PDGFRB |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
114 | Relaxin signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
115 | Retrograde endocannabinoid signaling 24 genes, 3 drugs (DrugBank) and 7 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00225 |
Alprazolam |
1件: 8 |
4件: GRIA1, GRIA2, GRIA3, GRIA4 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
116 | RIG-I-like receptor signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
117 | Salivary secretion 7 genes, 2 drugs (DrugBank) and 3 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
118 | Salmonella infection 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
119 | Serotonergic synapse 9 genes, 7 drugs (DrugBank) and 9 diseases shown |
3件: GABRB1, GABRB2, GABRB3 |
D00225 |
Alprazolam |
1件: 8 |
1件: HTR2A |
D00426 |
Risperidone |
5件: 8, 156, 179, 187, 206 |
4件: HTR2A, HTR2B, HTR2C, HTR6 |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A4 |
D00822 |
Citalopram |
3件: 8, 46, 127 |
D07704 |
D00825 |
Sertraline |
3件: 6, 8, 206 |
D02360 |
120 | Shigellosis 5 genes, 2 drugs (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
121 | Signaling pathways regulating pluripotency of stem cells 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
122 | Sphingolipid signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
123 | Steroid hormone biosynthesis 1 gene, 1 drug (DrugBank) and 3 diseases shown |
1件: CYP17A1 |
D00351 |
Ketoconazole |
3件: 8, 13, 75 |
124 | Synaptic vesicle cycle 4 genes, 6 drugs (DrugBank) and 7 diseases shown |
1件: SLC18A2 |
D08575 |
Tetrabenazine |
1件: 8 |
D10675 |
Valbenazine |
1件: 8 |
1件: SLC6A2 |
D02574 |
Atomoxetine |
3件: 6, 8, 13 |
D07473 |
2件: SLC6A2, SLC6A3 |
D00817 |
Bupropion |
2件: 8, 96 |
D07591 |
D07938 |
1件: SLC6A4 |
D00822 |
Citalopram |
3件: 8, 46, 127 |
D07704 |
D00825 |
Sertraline |
3件: 6, 8, 206 |
D02360 |
125 | Systemic lupus erythematosus 2 genes, 5 drugs (DrugBank) and 16 diseases shown |
2件: GRIN2A, GRIN2B |
D00777 |
Amantadine |
4件: 6, 8, 13, 127 |
D07441 |
D00848 |
Dextromethorphan |
9件: 2, 6, 8, 13, 46, 78, 96, 97, 156 |
D03742 |
D03744 |
D09917 |
Latrepirdine |
1件: 8 |
D04905 |
Memantine |
7件: 2, 6, 8, 13, 49, 127, 205 |
D08174 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
126 | T cell receptor signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
127 | Taste transduction 9 genes, 2 drugs (DrugBank) and 3 diseases shown |
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00225 |
Alprazolam |
1件: 8 |
3件: SCN2A, SCN3A, SCN9A |
D00642 |
Quinidine |
3件: 2, 8, 13 |
D00643 |
D02272 |
D08458 |
128 | Taurine and hypotaurine metabolism 2 genes, 1 drug (DrugBank) and 14 diseases shown |
2件: GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
129 | Th1 and Th2 cell differentiation 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
130 | Th17 cell differentiation 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
131 | Thermogenesis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
132 | Thyroid hormone signaling pathway 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
133 | Thyroid hormone synthesis 4 genes, 1 drug (DrugBank) and 2 diseases shown |
4件: ATP1A1, ATP1A2, ATP1A3, ATP1A4 |
D00298 |
Digoxin |
2件: 8, 46 |
134 | TNF signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
135 | Toll-like receptor signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
136 | Toxoplasmosis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
137 | Transcriptional misregulation in cancer 1 gene, 1 drug (DrugBank) and 7 diseases shown |
1件: GRIA3 |
D00775 |
Riluzole |
7件: 2, 3, 5, 8, 13, 17, 206 |
138 | Tuberculosis 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
139 | Type I diabetes mellitus 2 genes, 1 drug (DrugBank) and 14 diseases shown |
2件: GAD1, GAD2 |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
140 | Type II diabetes mellitus 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: CACNA1G |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
141 | Ubiquinone and other terpenoid-quinone biosynthesis 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: NQO1, VKORC1 |
D00564 |
Warfarin |
10件: 6, 8, 13, 19, 46, 49, 66, 85, 88, 96 |
D01280 |
D08682 |
142 | Valine, leucine and isoleucine degradation 1 gene, 1 drug (DrugBank) and 14 diseases shown |
1件: ABAT |
D00399 |
Valproic Acid |
14件: 2, 3, 5, 8, 26, 34, 65, 89, 90, 102, 222, 233, 256, 331 |
143 | Vascular smooth muscle contraction 3 genes, 1 drug (DrugBank) and 2 diseases shown |
3件: ADRA1A, ADRA1B, ADRA1D |
D00454 |
Olanzapine |
2件: 2, 8 |
D06623 |
144 | VEGF signaling pathway 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |
145 | Viral myocarditis 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: ABL1 |
D08953 |
Nilotinib |
5件: 6, 8, 34, 51, 86 |
146 | Yersinia infection 4 genes, 1 drug (DrugBank) and 1 disease shown |
4件: MAPK11, MAPK12, MAPK13, MAPK14 |
D10959 |
Neflamapimod |
1件: 8 |