No. |
KEGG PATHWAY * On map, Yellow: Drug target, Red: Disease-related |
KEGG GENES * |
KEGG DRUG * |
DrugBank |
指定難病告示番号 * |
1 | Adipocytokine signaling pathway 2 genes, 6 drugs (DrugBank) and 43 diseases shown |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
2 | Adrenergic signaling in cardiomyocytes 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: SCN5A |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
3 | African trypanosomiasis 6 genes, 7 drugs (DrugBank) and 49 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
4 | AGE-RAGE signaling pathway in diabetic complications 6 genes, 7 drugs (DrugBank) and 47 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
5 | Alcoholism 1 gene, 2 drugs (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D03215 |
Armodafinil |
3件: 6, 13, 84 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
6 | Aldosterone synthesis and secretion 1 gene, 1 drug (DrugBank) and 12 diseases shown |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
7 | Allograft rejection 6 genes, 7 drugs (DrugBank) and 52 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
8 | Alzheimer disease 2 genes, 6 drugs (DrugBank) and 47 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
9 | Amoebiasis 8 genes, 8 drugs (DrugBank) and 52 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
10 | Amphetamine addiction 1 gene, 2 drugs (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D03215 |
Armodafinil |
3件: 6, 13, 84 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
11 | AMPK signaling pathway 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
12 | Amyotrophic lateral sclerosis (ALS) 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
13 | Antifolate resistance 5 genes, 7 drugs (DrugBank) and 60 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
14 | Antigen processing and presentation 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
15 | Apoptosis 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
16 | Asthma 2 genes, 5 drugs (DrugBank) and 42 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
17 | Autoimmune thyroid disease 3 genes, 2 drugs (DrugBank) and 28 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
18 | Bile secretion 2 genes, 2 drugs (DrugBank) and 25 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
1件: NR1H4 |
D00734 |
Ursodeoxycholic acid |
12件: 6, 8, 20, 67, 84, 93, 94, 95, 96, 97, 234, 299 |
19 | C-type lectin receptor signaling pathway 7 genes, 7 drugs (DrugBank) and 49 diseases shown |
4件: IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
20 | Calcium signaling pathway 3 genes, 3 drugs (DrugBank) and 11 diseases shown |
1件: CHRNA7 |
D03365 |
Nicotine |
2件: 6, 84 |
D05156 |
D05157 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
21 | cAMP signaling pathway 7 genes, 5 drugs (DrugBank) and 25 diseases shown |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
22 | Cell adhesion molecules (CAMs) 2 genes, 1 drug (DrugBank) and 24 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
23 | Cellular senescence 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL1A, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
24 | cGMP-PKG signaling pathway 6 genes, 4 drugs (DrugBank) and 15 diseases shown |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PDE5A |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
25 | Chagas disease (American trypanosomiasis) 7 genes, 7 drugs (DrugBank) and 49 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
26 | Chemical carcinogenesis 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: CHRNA7 |
D03365 |
Nicotine |
2件: 6, 84 |
D05156 |
D05157 |
27 | Chemokine signaling pathway 4 genes, 3 drugs (DrugBank) and 15 diseases shown |
1件: CCL2 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
2件: JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
28 | Cholinergic synapse 7 genes, 2 drugs (DrugBank) and 10 diseases shown |
6件: CHRNA3, CHRNA4, CHRNA6, CHRNA7, CHRNB2, CHRNB4 |
D03365 |
Nicotine |
2件: 6, 84 |
D05156 |
D05157 |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
29 | Circadian entrainment 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
30 | Cocaine addiction 1 gene, 2 drugs (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D03215 |
Armodafinil |
3件: 6, 13, 84 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
31 | Complement and coagulation cascades 1 gene, 1 drug (DrugBank) and 11 diseases shown |
1件: SERPINC1 |
D07510 |
Heparin |
11件: 60, 70, 79, 84, 107, 224, 226, 280, 299, 316, 317 |
32 | Cortisol synthesis and secretion 1 gene, 1 drug (DrugBank) and 12 diseases shown |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
33 | Cushing syndrome 1 gene, 1 drug (DrugBank) and 12 diseases shown |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
34 | Cytokine-cytokine receptor interaction 13 genes, 10 drugs (DrugBank) and 52 diseases shown |
6件: CCL2, IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
35 | Cytosolic DNA-sensing pathway 2 genes, 2 drugs (DrugBank) and 17 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
36 | Dilated cardiomyopathy (DCM) 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
37 | Dopaminergic synapse 2 genes, 3 drugs (DrugBank) and 14 diseases shown |
1件: SCN1A |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
1件: SLC6A3 |
D03215 |
Armodafinil |
3件: 6, 13, 84 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
38 | Drug metabolism - other enzymes 2 genes, 1 drug (DrugBank) and 34 diseases shown |
2件: IMPDH1, IMPDH2 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
39 | EGFR tyrosine kinase inhibitor resistance 4 genes, 3 drugs (DrugBank) and 16 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
40 | Endocrine and other factor-regulated calcium reabsorption 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: VDR |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
41 | Endocytosis 1 gene, 1 drug (DrugBank) and 2 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
42 | Epstein-Barr virus infection 5 genes, 6 drugs (DrugBank) and 43 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
43 | Fc epsilon RI signaling pathway 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
44 | Fluid shear stress and atherosclerosis 6 genes, 7 drugs (DrugBank) and 51 diseases shown |
4件: CCL2, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
45 | Folate biosynthesis 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
46 | FoxO signaling pathway 2 genes, 1 drug (DrugBank) and 10 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
47 | GABAergic synapse 16 genes, 1 drug (DrugBank) and 8 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
48 | Gap junction 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
49 | Gastric acid secretion 1 gene, 1 drug (DrugBank) and 8 diseases shown |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
50 | Graft-versus-host disease 6 genes, 7 drugs (DrugBank) and 56 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
51 | Growth hormone synthesis, secretion and action 2 genes, 2 drugs (DrugBank) and 15 diseases shown |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
52 | Hematopoietic cell lineage 8 genes, 9 drugs (DrugBank) and 72 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
1件: MS4A1 |
D02994 |
Rituximab |
42件: 11, 13, 14, 17, 35, 36, 43, 44, 45, 46, 49, 50, 51, 52, 53, 56, 60, 61, 63, 64, 65, 66, 83, 84, 85, 86, 93, 94, 96, 97, 162, 222, 223, 229, 256, 271, 283, 284, 285, 288, 300, 331 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
53 | Hepatitis B 6 genes, 6 drugs (DrugBank) and 43 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
54 | Hepatitis C 3 genes, 6 drugs (DrugBank) and 43 diseases shown |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
55 | Herpes simplex virus 1 infection 9 genes, 8 drugs (DrugBank) and 49 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
56 | HIF-1 signaling pathway 2 genes, 2 drugs (DrugBank) and 13 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
57 | Human cytomegalovirus infection 8 genes, 10 drugs (DrugBank) and 51 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
1件: JAK1 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
58 | Human immunodeficiency virus 1 infection 2 genes, 6 drugs (DrugBank) and 42 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
59 | Human papillomavirus infection 3 genes, 6 drugs (DrugBank) and 43 diseases shown |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
60 | Human T-cell leukemia virus 1 infection 6 genes, 7 drugs (DrugBank) and 49 diseases shown |
2件: IL1R1, IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: JAK1, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
61 | Hypertrophic cardiomyopathy (HCM) 2 genes, 5 drugs (DrugBank) and 42 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
62 | IL-17 signaling pathway 4 genes, 6 drugs (DrugBank) and 47 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
63 | Inflammatory bowel disease (IBD) 8 genes, 7 drugs (DrugBank) and 49 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
64 | Inflammatory mediator regulation of TRP channels 2 genes, 3 drugs (DrugBank) and 27 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
65 | Influenza A 10 genes, 8 drugs (DrugBank) and 49 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
66 | Insulin resistance 2 genes, 5 drugs (DrugBank) and 42 diseases shown |
2件: IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
67 | Intestinal immune network for IgA production 4 genes, 2 drugs (DrugBank) and 28 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
68 | JAK-STAT signaling pathway 10 genes, 4 drugs (DrugBank) and 24 diseases shown |
2件: IL10, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
69 | Kaposi sarcoma-associated herpesvirus infection 6 genes, 4 drugs (DrugBank) and 28 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
70 | Legionellosis 5 genes, 7 drugs (DrugBank) and 49 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
71 | Leishmaniasis 8 genes, 8 drugs (DrugBank) and 49 diseases shown |
4件: IL10, IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
72 | Long-term depression 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
73 | Malaria 6 genes, 7 drugs (DrugBank) and 49 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL12A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
74 | MAPK signaling pathway 4 genes, 7 drugs (DrugBank) and 51 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
75 | Measles 8 genes, 4 drugs (DrugBank) and 28 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: JAK1, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
76 | Melanogenesis 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
77 | Metabolic pathways 13 genes, 6 drugs (DrugBank) and 60 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
2件: IMPDH1, IMPDH2 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
1件: PDE5A |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
78 | Mineral absorption 1 gene, 1 drug (DrugBank) and 5 diseases shown |
1件: VDR |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
79 | Morphine addiction 20 genes, 2 drugs (DrugBank) and 9 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
80 | mTOR signaling pathway 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
81 | Natural killer cell mediated cytotoxicity 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
82 | Necroptosis 7 genes, 7 drugs (DrugBank) and 47 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
83 | Neuroactive ligand-receptor interaction 38 genes, 14 drugs (DrugBank) and 74 diseases shown |
16件: CHRNA1, CHRNA10, CHRNA2, CHRNA3, CHRNA4, CHRNA5, CHRNA6, CHRNA7, CHRNA9, CHRNB1, CHRNB2, CHRNB3, CHRNB4, CHRND, CHRNE, CHRNG |
D03365 |
Nicotine |
2件: 6, 84 |
D05156 |
D05157 |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
1件: MC2R |
D00146 |
Corticotropin |
12件: 2, 13, 46, 49, 50, 66, 75, 78, 84, 145, 193, 222 |
1件: NR3C1 |
D01703 |
Ciclesonide |
1件: 84 |
D00292 |
Dexamethasone |
20件: 13, 16, 28, 35, 46, 53, 63, 65, 70, 74, 75, 81, 83, 84, 90, 96, 97, 222, 296, 299 |
D00975 |
D01510 |
D01615 |
D01632 |
D01948 |
D02174 |
D02591 |
D02592 |
D00407 |
Methylprednisolone |
36件: 2, 13, 25, 26, 35, 38, 39, 40, 41, 42, 43, 45, 46, 49, 50, 51, 60, 63, 64, 65, 66, 83, 84, 86, 96, 97, 145, 164, 220, 222, 224, 271, 283, 284, 285, 296 |
D00751 |
D00979 |
D05000 |
D05001 |
D05002 |
D00472 |
Prednisolone |
38件: 11, 13, 25, 26, 35, 38, 39, 41, 43, 44, 45, 46, 49, 50, 51, 56, 60, 61, 63, 64, 65, 66, 75, 81, 84, 85, 95, 96, 97, 113, 145, 162, 222, 269, 271, 296, 299, 300 |
D00980 |
D00981 |
D00982 |
D01239 |
D01998 |
D02156 |
D03301 |
D00473 |
Prednisone |
44件: 2, 11, 13, 14, 26, 35, 40, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 61, 63, 64, 65, 66, 81, 84, 85, 86, 95, 96, 97, 113, 145, 162, 164, 222, 224, 228, 251, 283, 284, 285, 288, 299, 300, 331 |
1件: PTGIR |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
1件: SSTR2 |
D00442 |
Octreotide |
8件: 67, 75, 84, 85, 89, 96, 193, 227 |
D06495 |
84 | NF-kappa B signaling pathway 3 genes, 7 drugs (DrugBank) and 51 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
85 | Nicotine addiction 20 genes, 2 drugs (DrugBank) and 8 diseases shown |
4件: CHRNA4, CHRNA6, CHRNA7, CHRNB2 |
D03365 |
Nicotine |
2件: 6, 84 |
D05156 |
D05157 |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
86 | NOD-like receptor signaling pathway 6 genes, 7 drugs (DrugBank) and 47 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
87 | Non-alcoholic fatty liver disease (NAFLD) 5 genes, 7 drugs (DrugBank) and 47 diseases shown |
4件: IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
88 | Non-small cell lung cancer 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
89 | One carbon pool by folate 2 genes, 1 drug (DrugBank) and 33 diseases shown |
2件: DHFR, DHFR2 |
D00142 |
Methotrexate |
33件: 11, 13, 19, 34, 35, 41, 42, 43, 44, 45, 46, 49, 50, 51, 53, 55, 56, 60, 62, 65, 84, 93, 96, 97, 162, 164, 172, 256, 271, 284, 285, 326, 331 |
D02115 |
90 | Osteoclast differentiation 6 genes, 8 drugs (DrugBank) and 51 diseases shown |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
2件: JAK1, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
91 | Oxytocin signaling pathway 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
92 | Pancreatic cancer 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: JAK1 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
93 | Parathyroid hormone synthesis, secretion and action 5 genes, 2 drugs (DrugBank) and 5 diseases shown |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
1件: VDR |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
94 | Parkinson disease 1 gene, 2 drugs (DrugBank) and 7 diseases shown |
1件: SLC6A3 |
D03215 |
Armodafinil |
3件: 6, 13, 84 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
95 | Pathogenic Escherichia coli infection 4 genes, 7 drugs (DrugBank) and 51 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
96 | Pathways in cancer 10 genes, 6 drugs (DrugBank) and 29 diseases shown |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
2件: EDNRA, EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
97 | PD-L1 expression and PD-1 checkpoint pathway in cancer 2 genes, 1 drug (DrugBank) and 9 diseases shown |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
98 | Pertussis 8 genes, 7 drugs (DrugBank) and 49 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
99 | PI3K-Akt signaling pathway 5 genes, 3 drugs (DrugBank) and 16 diseases shown |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
100 | Platelet activation 4 genes, 4 drugs (DrugBank) and 8 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PTGIR |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
101 | Primary immunodeficiency 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
102 | Prion diseases 3 genes, 2 drugs (DrugBank) and 17 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
103 | Prolactin signaling pathway 1 gene, 1 drug (DrugBank) and 9 diseases shown |
1件: JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
104 | Prostate cancer 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
105 | Proteoglycans in cancer 2 genes, 6 drugs (DrugBank) and 44 diseases shown |
1件: IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
106 | Purine metabolism 10 genes, 4 drugs (DrugBank) and 41 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
2件: IMPDH1, IMPDH2 |
D05096 |
Mycophenolic acid |
34件: 2, 11, 13, 14, 19, 20, 28, 35, 36, 42, 43, 45, 49, 51, 53, 60, 62, 65, 66, 84, 85, 95, 96, 162, 164, 222, 224, 226, 228, 234, 283, 284, 285, 300 |
4件: PDE4A, PDE4B, PDE4C, PDE4D |
D05744 |
Roflumilast |
2件: 84, 299 |
1件: PDE5A |
D02008 |
Tadalafil |
6件: 6, 51, 75, 84, 86, 113 |
107 | Relaxin signaling pathway 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: EDNRB |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
108 | Renin secretion 4 genes, 3 drugs (DrugBank) and 12 diseases shown |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
109 | Retrograde endocannabinoid signaling 16 genes, 1 drug (DrugBank) and 8 diseases shown |
16件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6, GABRB1, GABRB2, GABRB3, GABRD, GABRE, GABRG1, GABRG2, GABRG3, GABRP, GABRQ |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
110 | Rheumatoid arthritis 8 genes, 8 drugs (DrugBank) and 56 diseases shown |
5件: CCL2, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
111 | RIG-I-like receptor signaling pathway 3 genes, 6 drugs (DrugBank) and 44 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
112 | Salivary secretion 3 genes, 1 drug (DrugBank) and 6 diseases shown |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
113 | Salmonella infection 3 genes, 2 drugs (DrugBank) and 17 diseases shown |
3件: IL1A, IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
114 | Serotonergic synapse 3 genes, 1 drug (DrugBank) and 8 diseases shown |
3件: GABRB1, GABRB2, GABRB3 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
115 | Shigellosis 3 genes, 7 drugs (DrugBank) and 51 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
116 | Signaling pathways regulating pluripotency of stem cells 3 genes, 1 drug (DrugBank) and 9 diseases shown |
3件: JAK1, JAK2, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
117 | Sphingolipid signaling pathway 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
118 | Staphylococcus aureus infection 1 gene, 1 drug (DrugBank) and 10 diseases shown |
1件: IL10 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
119 | Synaptic vesicle cycle 2 genes, 2 drugs (DrugBank) and 7 diseases shown |
2件: SLC6A2, SLC6A3 |
D01296 |
Methylphenidate |
7件: 6, 13, 34, 84, 113, 179, 206 |
D04999 |
1件: SLC6A3 |
D03215 |
Armodafinil |
3件: 6, 13, 84 |
120 | Systemic lupus erythematosus 4 genes, 6 drugs (DrugBank) and 52 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
121 | T cell receptor signaling pathway 2 genes, 5 drugs (DrugBank) and 42 diseases shown |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
122 | Taste transduction 9 genes, 2 drugs (DrugBank) and 15 diseases shown |
6件: GABRA1, GABRA2, GABRA3, GABRA4, GABRA5, GABRA6 |
D00549 |
Propofol |
8件: 6, 21, 22, 34, 46, 84, 98, 296 |
3件: SCN2A, SCN3A, SCN9A |
D00358 |
Lidocaine |
10件: 6, 13, 46, 84, 86, 97, 168, 226, 231, 256 |
D02086 |
D08127 |
123 | Terpenoid backbone biosynthesis 1 gene, 1 drug (DrugBank) and 17 diseases shown |
1件: HMGCR |
D00887 |
Atorvastatin |
17件: 13, 46, 49, 51, 58, 63, 79, 84, 88, 93, 96, 160, 222, 225, 265, 271, 299 |
D07474 |
124 | TGF-beta signaling pathway 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
125 | Th1 and Th2 cell differentiation 6 genes, 2 drugs (DrugBank) and 18 diseases shown |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
126 | Th17 cell differentiation 9 genes, 6 drugs (DrugBank) and 33 diseases shown |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: IL1B, IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1R1 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
4件: JAK1, JAK2, JAK3, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
127 | TNF signaling pathway 4 genes, 6 drugs (DrugBank) and 47 diseases shown |
4件: CCL2, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
128 | Toll-like receptor signaling pathway 7 genes, 8 drugs (DrugBank) and 56 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
3件: IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
129 | Toxoplasmosis 8 genes, 8 drugs (DrugBank) and 45 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
2件: IL10, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
3件: JAK1, JAK2, TYK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
130 | Transcriptional misregulation in cancer 3 genes, 3 drugs (DrugBank) and 36 diseases shown |
1件: CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
1件: IL1R2 |
D02934 |
Anakinra |
17件: 2, 13, 15, 19, 37, 41, 46, 49, 50, 56, 65, 84, 86, 106, 107, 266, 299 |
1件: IL6 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
131 | Tuberculosis 11 genes, 9 drugs (DrugBank) and 50 diseases shown |
5件: IL10, IL1A, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
3件: IL12A, IL12B, IL23A |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
2件: JAK1, JAK2 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
1件: VDR |
D00187 |
Ergocalciferol |
5件: 46, 84, 96, 97, 299 |
132 | Type I diabetes mellitus 7 genes, 8 drugs (DrugBank) and 56 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
2件: IL12A, IL12B |
D09214 |
Ustekinumab |
16件: 13, 37, 41, 46, 49, 50, 53, 56, 65, 84, 93, 96, 97, 162, 269, 271 |
3件: IL1A, IL1B, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
133 | Type II diabetes mellitus 1 gene, 5 drugs (DrugBank) and 42 diseases shown |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
134 | Vascular smooth muscle contraction 5 genes, 6 drugs (DrugBank) and 13 diseases shown |
1件: EDNRA |
D07077 |
Ambrisentan |
6件: 51, 84, 85, 86, 88, 211 |
D01227 |
Bosentan |
10件: 13, 41, 47, 51, 84, 85, 86, 88, 210, 211 |
D07538 |
3件: GUCY1A1, GUCY1A2, GUCY1B1 |
D09572 |
Riociguat |
6件: 51, 84, 86, 88, 225, 299 |
1件: PTGIR |
D02721 |
Iloprost |
4件: 51, 84, 85, 86 |
D09994 |
Selexipag |
5件: 51, 70, 84, 86, 88 |
D06213 |
Treprostinil |
5件: 51, 84, 85, 86, 88 |
135 | Viral carcinogenesis 3 genes, 2 drugs (DrugBank) and 9 diseases shown |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
2件: JAK1, JAK3 |
D09970 |
Tofacitinib |
9件: 46, 49, 50, 51, 84, 96, 97, 107, 271 |
136 | Viral myocarditis 2 genes, 1 drug (DrugBank) and 24 diseases shown |
2件: CD80, CD86 |
D03203 |
Abatacept |
24件: 11, 13, 19, 41, 44, 46, 49, 50, 51, 53, 55, 60, 65, 84, 93, 96, 97, 107, 164, 222, 271, 284, 285, 300 |
137 | Viral protein interaction with cytokine and cytokine receptor 6 genes, 7 drugs (DrugBank) and 43 diseases shown |
4件: CCL2, IL10, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: CCR5 |
D06670 |
Maraviroc |
2件: 46, 84 |
1件: IL6R |
D10161 |
Sarilumab |
5件: 41, 46, 84, 107, 271 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |
138 | Yersinia infection 5 genes, 6 drugs (DrugBank) and 47 diseases shown |
5件: CCL2, IL10, IL1B, IL6, TNF |
D01583 |
Pirfenidone |
10件: 34, 46, 50, 51, 58, 84, 85, 164, 222, 228 |
1件: IL1B |
D09315 |
Canakinumab |
9件: 46, 56, 84, 106, 107, 108, 113, 266, 269 |
1件: TNF |
D02597 |
Adalimumab |
15件: 19, 37, 41, 46, 56, 84, 96, 97, 151, 160, 164, 222, 226, 269, 271 |
D04358 |
Golimumab |
5件: 46, 84, 96, 97, 271 |
D02598 |
Infliximab |
23件: 35, 37, 38, 39, 40, 41, 43, 45, 46, 49, 50, 56, 65, 84, 85, 95, 96, 97, 98, 162, 164, 269, 271 |
D00754 |
Thalidomide |
18件: 2, 16, 20, 28, 49, 51, 53, 65, 84, 85, 94, 96, 97, 227, 271, 280, 298, 331 |