No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
Aln-cc5 |
- |
- |
- |
- |
[2] 62, 109 |
2 |
Alxn1210 |
- |
- |
- |
- |
[2] 62, 109 |
3 |
Anti-c5 antibody |
- |
- |
- |
- |
[4] 11, 14, 62, 109 |
4 |
Ccx168 |
- |
- |
- |
- |
[6] 43, 44, 66, 109, 222, 223 |
5 |
Cemdisiran |
- |
- |
- |
- |
[2] 66, 109 |
6 |
Coversin |
Nomacopan |
D11473 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[2] 62, 109 |
7 |
Eculizumab |
Eculizumab |
D03940 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[7] 11, 13, 14, 62, 109, 222, 223 |
8 |
Fc- and cdr-modified humanised monoclonal antibody against c5 |
- |
- |
- |
- |
[2] 62, 109 |
9 |
Oms00620646, oms620646, masp-2 antibody |
- |
- |
- |
- |
[1] 109 |
10 |
Oms721 |
- |
- |
- |
- |
[5] 64, 66, 109, 222, 223 |
11 |
Oms721 100 mg/ml injection solution, oms00620646, oms620646, masp-2 antibody |
- |
- |
- |
- |
[2] 64, 109 |
12 |
Oms721 185 mg/ml injection solution, oms00620646, oms620646, masp-2 antibody |
- |
- |
- |
- |
[2] 64, 109 |
13 |
Oms721 drug product 185 mg/ml |
- |
- |
- |
- |
[1] 109 |
14 |
Ravulizumab |
Ravulizumab |
D11054 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[3] 11, 62, 109 |
15 |
Rva576 |
- |
- |
- |
- |
[3] 62, 109, 162 |
16 |
Rva576 (coversin) |
Nomacopan |
D11473 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[2] 62, 109 |
17 |
Soliris |
Eculizumab |
D03940 |
[1] C5 |
[7] Complement and coagulation cascades, Herpes simplex virus 1 infection, Neuroactive ligand-receptor interaction, Pertussis, Prion diseases, Staphylococcus aureus infection, Systemic lupus erythematosus |
[7] 11, 13, 14, 62, 109, 222, 223 |