No. |
Drug (Description in trials) |
DrugBank |
KEGG DRUG * |
KEGG GENES * [Number of genes] |
KEGG PATHWAY [Number of pathways] |
Disease ID * [Number of diseases] |
1 |
0.9% sodium chloride injection |
Sodium chloride |
D02056 |
- |
- |
[1] 168 |
2 |
Bupivacaine |
Bupivacaine |
D01450, D07552 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[7] 46, 53, 70, 96, 168, 226, 298 |
3 |
Bupivacaine injection 0.5% |
Bupivacaine |
D01450, D07552 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 168 |
4 |
Celiprolol |
Celiprolol |
D07660 |
[1] ADRB1 |
[10] Adrenergic signaling in cardiomyocytes, Calcium signaling pathway, Dilated cardiomyopathy (DCM), Gap junction, Neuroactive ligand-receptor interaction, Regulation of lipolysis in adipocytes, Renin secretion, Salivary secretion, cAMP signaling pathway, cGMP-PKG signaling pathway |
[1] 168 |
5 |
Chloride |
Chloride ion |
- |
- |
- |
[17] 6, 11, 13, 14, 34, 46, 51, 96, 97, 127, 168, 193, 227, 228, 288, 297, 299 |
6 |
Control |
Chloroxylenol |
D03473 |
- |
- |
[4] 6, 13, 46, 168 |
7 |
Irbesartan |
Irbesartan |
D00523 |
[1] AGTR1 |
[14] AGE-RAGE signaling pathway in diabetic complications, Adrenergic signaling in cardiomyocytes, Aldosterone synthesis and secretion, Apelin signaling pathway, Calcium signaling pathway, Cortisol synthesis and secretion, Cushing syndrome, Neuroactive ligand-receptor interaction, Pathways in cancer, Phospholipase D signaling pathway, Renin secretion, Renin-angiotensin system, Vascular smooth muscle contraction, cGMP-PKG signaling pathway |
[4] 66, 167, 168, 222 |
8 |
Lidocaine |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[8] 6, 13, 46, 86, 168, 226, 231, 256 |
9 |
Lidocaine injection 2% |
Lidocaine |
D00358, D02086, D08127 |
[5] SCN1A, SCN2A, SCN3A, SCN5A, SCN9A |
[3] Adrenergic signaling in cardiomyocytes, Dopaminergic synapse, Taste transduction |
[1] 168 |
10 |
Mecasermin |
Mecasermin |
D03297, D04870 |
[2] GHR, IGF1R |
[33] AMPK signaling pathway, Adherens junction, Autophagy - animal, Breast cancer, Cytokine-cytokine receptor interaction, EGFR tyrosine kinase inhibitor resistance, Endocrine resistance, Endocytosis, Focal adhesion, FoxO signaling pathway, Glioma, Growth hormone synthesis, secretion and action, HIF-1 signaling pathway, Hepatocellular carcinoma, JAK-STAT signaling pathway, Long-term depression, Longevity regulating pathway, Longevity regulating pathway - multiple species, MAPK signaling pathway, Melanoma, Neuroactive ligand-receptor interaction, Oocyte meiosis, Ovarian steroidogenesis, PI3K-Akt signaling pathway, Pathways in cancer, Progesterone-mediated oocyte maturation, Prostate cancer, Proteoglycans in cancer, Rap1 signaling pathway, Ras signaling pathway, Signaling pathways regulating pluripotency of stem cells, Transcriptional misregulation in cancer, mTOR signaling pathway |
[5] 78, 96, 168, 265, 299 |
11 |
Mind-body therapy |
- |
- |
- |
- |
[1] 168 |
12 |
Riboflavin |
Riboflavin |
D00050, D01622, D01913 |
- |
- |
[8] 13, 38, 46, 96, 97, 162, 168, 265 |
13 |
Saline |
Sodium chloride |
D02056 |
- |
- |
[10] 6, 13, 17, 53, 67, 78, 86, 97, 168, 299 |
14 |
Sodium chloride |
Sodium chloride |
D02056 |
- |
- |
[13] 6, 11, 13, 14, 34, 46, 51, 168, 193, 227, 228, 288, 299 |